A monoclonal antibody (Po66) directed against human lung squamous cell carcinoma immunolocalization of tumour xenografts in nude mice

1987 ◽  
Vol 24 (3) ◽  
Author(s):  
L�ontine Dazord ◽  
Dominique Bourel ◽  
Anne Martin ◽  
Rozenn Lecorre ◽  
Patrick Bourguet ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Nude Mice ◽  
Human Lung ◽  
Lung Squamous Cell Carcinoma ◽  
Tumour Xenografts

Purification of a Tumoral Marker Recognized by Monoclonal Antibody Po66 and Associated with Human Lung Squamous Cell Carcinoma

1996 ◽  
Vol 11 (3) ◽  
pp. 148-152 ◽  
Author(s):  
F. Brichory ◽  
B. Collet ◽  
C. Pineau ◽  
B. Desrues ◽  
L. Toujas ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Cell Line ◽  
Squamous Cell ◽  
Human Lung ◽  
Lung Squamous Cell Carcinoma ◽  
Squamous Carcinoma ◽  
Prolonged Retention ◽  
Squamous Carcinoma Cell

Monoclonal antibody (MAb) Po66, a murine IgG1, was raised by immunization against human lung squamous cell carcinoma. When injected intravenously, Po66 showed prolonged retention in the tumor. It recognized an intracellular antigen. The human lung squamous carcinoma cell line SK-MES-1 expresses the antigen recognized by MAb Po66 and was used as a source of biological material for its purification. The SK-MES-1 cell line was labeled in culture with [35S]methionine and its lysate was immunoprecipitated with Po66 immobilized on Protein G-Sepharose. The precipitate contained three proteins (47, 50 and 69 kDa) absent in the controls. The 69 kDa polypeptide was further purified by anion exchange and immunoaffinity chromatographies. To date, no other tumor marker expressed in non-small cell lung cancer with these characteristics has been described and as such this marker is interesting for future use in immunotherapy and in diagnosis.

scholarly journals Immunoscintigraphy of human lung squamous cell carcinoma using an iodine-131 labelled monoclonal antibody (Po66)

1990 ◽  
Vol 61 (2) ◽  
pp. 230-234 ◽  
Author(s):  
P Bourguet ◽  
L Dazord ◽  
B Desrues ◽  
B Collet ◽  
MP Ramee ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Human Lung ◽  
Lung Squamous Cell Carcinoma ◽  
Iodine 131

The effect of radioimmunotherapy using murine monoclonal antibody KIS1 on esophageal squamous cell carcinoma-bearing nude mice

Surgery Today ◽  
1997 ◽  
Vol 27 (11) ◽  
pp. 1026-1034 ◽  
Author(s):  
Teruhiko Fujii ◽  
Hideaki Yamana ◽  
Yuji Toh ◽  
Uhi Toh ◽  
Hiromasa Fujita ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Nude Mice ◽  
Murine Monoclonal Antibody

scholarly journals Identification of reference genes for qRT-PCR in human lung squamous-cell carcinoma by RNA-Seq

2014 ◽  
Vol 46 (4) ◽  
pp. 330-337 ◽  
Author(s):  
Cheng Zhan ◽  
Yongxing Zhang ◽  
Jun Ma ◽  
Lin Wang ◽  
Wei Jiang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Reference Genes ◽  
Human Lung ◽  
Lung Squamous Cell Carcinoma ◽  
Rna Seq ◽  
Qrt Pcr

scholarly journals Terminal N-Acetylgalactosamine-Specific Leguminous Lectin from Wisteria japonica as a Probe for Human Lung Squamous Cell Carcinoma

PLoS ONE ◽  
2013 ◽  
Vol 8 (12) ◽  
pp. e83886 ◽  
Author(s):  
Keisuke Soga ◽  
Futaba Teruya ◽  
Hiroaki Tateno ◽  
Jun Hirabayashi ◽  
Kazuo Yamamoto
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Human Lung ◽  
Lung Squamous Cell Carcinoma ◽  
Leguminous Lectin

Cytogenetic comparison of two poorly differentiated human lung squamous cell carcinoma lines

1992 ◽  
Vol 59 (2) ◽  
pp. 111-118 ◽  
Author(s):  
Elizabeth Law ◽  
Una Gilvarry ◽  
Vincent Lynch ◽  
Bernard Gregory ◽  
Geraldine Grant ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Human Lung ◽  
Lung Squamous Cell Carcinoma ◽  
Poorly Differentiated
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