High-resolution solution structure of two members of a conformationally homogeneous combinatorial peptide library based on the classical zinc-finger motif

1996 ◽  
Vol 8 (1) ◽  
Author(s):  
Gaetano Barbato ◽  
DanielO. Cicero ◽  
Elisabetta Bianchi ◽  
Antonello Pessi ◽  
Renzo Bazzo
Keyword(s):  
High Resolution ◽  
Zinc Finger ◽  
Solution Structure ◽  
Peptide Library ◽  
Zinc Finger Motif ◽  
Combinatorial Peptide Library

High-resolution solution structure of the double Cys2His2 zinc finger from the human enhancer binding protein MBP-1

Biochemistry ◽  
1992 ◽  
Vol 31 (16) ◽  
pp. 3907-3917 ◽  
Author(s):  
James G. Omichinski ◽  
G. Marius Clore ◽  
Mark Robien ◽  
Kazuyasu Sakaguchi ◽  
Ettore Appella ◽  
...  
Keyword(s):  
High Resolution ◽  
Zinc Finger ◽  
Solution Structure ◽  
Binding Protein ◽  
Enhancer Binding Protein

scholarly journals Solution structure of the U2 snRNP protein Rds3p reveals a knotted zinc-finger motif

2008 ◽  
Vol 105 (28) ◽  
pp. 9621-9626 ◽  
Author(s):  
A.-M. M. van Roon ◽  
N. M. Loening ◽  
E. Obayashi ◽  
J.-C. Yang ◽  
A. J. Newman ◽  
...  
Keyword(s):  
Zinc Finger ◽  
Solution Structure ◽  
Zinc Finger Motif ◽  
U2 Snrnp ◽  
Snrnp Protein

Rapid Identification of Substrates for Novel Proteases Using a Combinatorial Peptide Library

2000 ◽  
Vol 2 (5) ◽  
pp. 461-466 ◽  
Author(s):  
Gérard Rossé ◽  
Erich Kueng ◽  
Malcolm G. P. Page ◽  
Vesna Schauer-Vukasinovic ◽  
Thomas Giller ◽  
...  
Keyword(s):  
Rapid Identification ◽  
Peptide Library ◽  
Combinatorial Peptide Library

scholarly journals The LIM/double zinc-finger motif functions as a protein dimerization domain.

1994 ◽  
Vol 91 (22) ◽  
pp. 10655-10659 ◽  
Author(s):  
R. Feuerstein ◽  
X. Wang ◽  
D. Song ◽  
N. E. Cooke ◽  
S. A. Liebhaber
Keyword(s):  
Zinc Finger ◽  
Zinc Finger Motif ◽  
Dimerization Domain ◽  
Protein Dimerization

scholarly journals Solution structure of the FCS zinc finger domain of the human polycomb group protein L(3)mbt-like 2

2009 ◽  
Vol 18 (3) ◽  
pp. 657-661 ◽  
Author(s):  
Bernhard C. Lechtenberg ◽  
Mark D. Allen ◽  
Trevor J. Rutherford ◽  
Stefan M. V. Freund ◽  
Mark Bycroft
Keyword(s):  
Zinc Finger ◽  
Solution Structure ◽  
Polycomb Group ◽  
Zinc Finger Domain ◽  
Polycomb Group Protein ◽  
Protein L ◽  
Group Protein

muscleblind, a gene required for photoreceptor differentiation in Drosophila, encodes novel nuclear Cys3His-type zinc-finger-containing proteins

Development ◽  
1997 ◽  
Vol 124 (21) ◽  
pp. 4321-4331 ◽  
Author(s):  
G. Begemann ◽  
N. Paricio ◽  
R. Artero ◽  
I. Kiss ◽  
M. Perez-Alonso ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Zinc Finger ◽  
Molecular Analysis ◽  
Neural Differentiation ◽  
General Factor ◽  
Lethal Gene ◽  
Zinc Finger Motif ◽  
Embryonic Lethal ◽  
Phenotype Analysis ◽  
Mutant Cells

We have isolated the embryonic lethal gene muscleblind (mbl) as a suppressor of the sev-svp2 eye phenotype. Analysis of clones mutant for mbl during eye development shows that it is autonomously required for photoreceptor differentiation. Mutant cells are recruited into developing ommatidia and initiate neural differentiation, but they fail to properly differentiate as photoreceptors. Molecular analysis reveals that the mbl locus is large and complex, giving rise to multiple different proteins with common 5′ sequences but different carboxy termini. Mbl proteins are nuclear and share a Cys3His zinc-finger motif which is also found in the TIS11/NUP475/TTP family of proteins and is highly conserved in vertebrates and invertebrates. Functional analysis of mbl, the observation that it also dominantly suppresses the sE-Jun(Asp) gain-of-function phenotype and the phenotypic similarity to mutants in the photoreceptor-specific glass gene suggest that mbl is a general factor required for photoreceptor differentiation.

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