The 1940s witnessed the appearance of a handful of scientists who, defying the specialism characteristic of most of 20th-century science, strode easily across borders erected to protect disciplinary territories. They were people who, had they been familiar with the poetry of the Nobel laureate Indian poet–philosopher Rabindranath Tagore (1861– 1941), would have shared his vision of a “heaven of freedom”: . . .Where the world has not been broken up into fragments by narrow domestic walls. . . . Norbert Wiener (1894–1964), logician, mathematician, and prodigy, who was awarded a PhD by Harvard at age 17, certainly yearned for this heaven of freedom in the realm of science as the war-weary first half of the 20th century came to an end. He would write that he and his fellow scientist and collaborator Arturo Rosenbluth (1900–1970) had long shared a belief that, although during the past two centuries scientific investigations became increasingly specialized, the most “fruitful” arenas lay in the “no-man’s land” between the established fields of science. There were scientific fields, Wiener remarked, that had been studied from different sides, each bestowing its own name to the field, each ignorant of what others had discovered, thus creating work that was “triplicated or quadruplicated” because of mutual ignorance or incomprehension. Wiener, no respecter of “narrow domestic walls” would inhabit such “boundary regions” between mathematics, engineering, biology, and sociology, and create cybernetics, a science devoted to the study of feedback systems common to living organisms, machines, and social systems. Here was a science that straddled the no-man’s land between the traditionally separate domains of the natural and the artificial. Wiener’s invention of cybernetics after the end of World War II was a marker of a certain spirit of the times when, in the manner in which Wiener expressed his yearning, scientists began to create serious links between nature and artifact. It is inevitable that this no-man’s land between the natural and the artificial should be part of this story.