Island Grafts: A Model for Studying Skin Regeneration in Isolation from other Processes

Author(s):  
Dennis P. Orgill ◽  
Charles E. Butler
Keyword(s):  
2013 ◽  
Vol 2 (2) ◽  
pp. 145-153 ◽  
Author(s):  
Mariana Cerqueira ◽  
Rui Reis ◽  
Alexendra Marques

2021 ◽  
pp. 2105080
Author(s):  
Luciana Y. Daikuara ◽  
Xifang Chen ◽  
Zhilian Yue ◽  
Danielle Skropeta ◽  
Fiona M. Wood ◽  
...  

2021 ◽  
Vol 6 (10) ◽  
pp. 3461-3472
Author(s):  
Shihao Zhang ◽  
Yamin Li ◽  
Xiaofeng Qiu ◽  
Anqi Jiao ◽  
Wei Luo ◽  
...  

Materials ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3337
Author(s):  
Sara Hooshmand ◽  
Sahar Mollazadeh ◽  
Negar Akrami ◽  
Mehrnoosh Ghanad ◽  
Ahmed El-Fiqi ◽  
...  

Exploring new therapies for managing skin wounds is under progress and, in this regard, mesoporous silica nanoparticles (MSNs) and mesoporous bioactive glasses (MBGs) offer great opportunities in treating acute, chronic, and malignant wounds. In general, therapeutic effectiveness of both MSNs and MBGs in different formulations (fine powder, fibers, composites etc.) has been proved over all the four stages of normal wound healing including hemostasis, inflammation, proliferation, and remodeling. The main merits of these porous substances can be summarized as their excellent biocompatibility and the ability of loading and delivering a wide range of both hydrophobic and hydrophilic bioactive molecules and chemicals. In addition, doping with inorganic elements (e.g., Cu, Ga, and Ta) into MSNs and MBGs structure is a feasible and practical approach to prepare customized materials for improved skin regeneration. Nowadays, MSNs and MBGs could be utilized in the concept of targeted therapy of skin malignancies (e.g., melanoma) by grafting of specific ligands. Since potential effects of various parameters including the chemical composition, particle size/morphology, textural properties, and surface chemistry should be comprehensively determined via cellular in vitro and in vivo assays, it seems still too early to draw a conclusion on ultimate efficacy of MSNs and MBGs in skin regeneration. In this regard, there are some concerns over the final fate of MSNs and MBGs in the wound site plus optimal dosages for achieving the best outcomes that deserve careful investigation in the future.


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pp. 50493
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Angélica Corral ◽  
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Chen Qin ◽  
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...  

2015 ◽  
Vol 44 (7) ◽  
pp. 1635-1641 ◽  
Author(s):  
Fateme Ahmadi-Aghkand ◽  
Shiva Gholizadeh-Ghaleh Aziz ◽  
Yunes Panahi ◽  
Hadis Daraee ◽  
Fateme Gorjikhah ◽  
...  

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