scholarly journals Reversible Cerebral White Matter Abnormalities in Homocystinuria

2018 ◽  
pp. 115-119 ◽  
Author(s):  
Naila Ismayilova ◽  
Andrew D. MacKinnon ◽  
Helen Mundy ◽  
Penny Fallon
2014 ◽  
Vol 222 (1-2) ◽  
pp. 52-59 ◽  
Author(s):  
Takeshi Asami ◽  
Sang Hyuk Lee ◽  
Sylvain Bouix ◽  
Yogesh Rathi ◽  
Thomas J. Whitford ◽  
...  

2014 ◽  
Vol 62 (11) ◽  
pp. 2209-2210 ◽  
Author(s):  
Hee-Won Jung ◽  
Sun-Wook Kim ◽  
Sol-Ji Yoon ◽  
Jung-Yeon Choi ◽  
Kwang-il Kim ◽  
...  

2009 ◽  
Vol 67 (3a) ◽  
pp. 689-691 ◽  
Author(s):  
Carla Graziadio ◽  
Rafael Fabiano Machado Rosa ◽  
Paulo Ricardo Gazzola Zen ◽  
Louise Lapagesse de Camargo Pinto ◽  
Liselotte Menke Barea ◽  
...  

2021 ◽  
Vol 15 ◽  
Author(s):  
Hui Juan Chen ◽  
Rongfeng Qi ◽  
Jun Ke ◽  
Jie Qiu ◽  
Qiang Xu ◽  
...  

Patients with posttraumatic stress disorder (PTSD) might have white matter abnormalities. However, less is known about white matter changes after exposing a specific traumatic event. The purpose of this study was to explore the abnormalities of diffusion in cerebral white matter and its relationship with the clinical symptoms in patients with PTSD by using diffusion tensor imaging (DTI). Diffusion-weighted imaging of the cerebrum was performed in typhoon survivors with (n = 27) and without PTSD (n = 33) and healthy controls (HCs) (n = 30). Differences in fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD) were calculated among groups using voxel-based analysis of the DTI data. Correlations between diffusion indices and clinical symptoms in patients with PTSD were also assessed. Both patients with PTSD and trauma-exposed control (TEC) group showed increased FA in the anterior limb of the internal capsule, forceps of the corpus callosum, and corona radiata relative to the HC group. Additionally, there was a negative correlation between FA values in the white matter and the clinical symptoms. Trauma exposure may result in disruption of cerebral white matter in individuals with or without PTSD, particularly in the frontal fibers. Aberrant white matter alterations may be associated with the severity of PTSD symptoms.


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