scholarly journals Improvement of Diffusion Tensor Imaging (DTI) Parameters with Decoppering Treatment in Wilson’s Disease

2015 ◽  
pp. 31-37 ◽  
Author(s):  
A. Lawrence ◽  
J. Saini ◽  
S. Sinha ◽  
S. Rao ◽  
M. Naggappa ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Wilson’S Disease ◽  
Diffusion Tensor ◽  
Wilson's Disease ◽  
Diffusion Tensor Imaging Dti

scholarly journals Diffusion Tensor Imaging (DTI) and its clinical correlates in drug naïve Wilson’s disease

2013 ◽  
Vol 28 (3) ◽  
pp. 455-462 ◽  
Author(s):  
Rakesh Jadav ◽  
Jitender Saini ◽  
Sanjib Sinha ◽  
Bhavanishankara Bagepally ◽  
S. Rao ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Wilson’S Disease ◽  
Diffusion Tensor ◽  
Wilson's Disease ◽  
Clinical Correlates ◽  
Drug Naïve ◽  
Diffusion Tensor Imaging Dti

Microstructure assessment of the thalamus in Wilson's disease using diffusion tensor imaging

2014 ◽  
Vol 69 (3) ◽  
pp. 294-298 ◽  
Author(s):  
G. Li ◽  
X. Zhou ◽  
P. Xu ◽  
X. Pan ◽  
Y. Chen
Keyword(s):  
Diffusion Tensor Imaging ◽  
Wilson’S Disease ◽  
Diffusion Tensor ◽  
Wilson's Disease

scholarly journals Study on Lesion Assessment of Cerebello-Thalamo-Cortical Network in Wilson’s Disease with Diffusion Tensor Imaging

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Anqin Wang ◽  
Hongli Wu ◽  
Chunsheng Xu ◽  
Lanfeng Tang ◽  
Jaeyoun Lee ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Basal Ganglia ◽  
Wilson’S Disease ◽  
Diffusion Tensor ◽  
Genetic Disorder ◽  
Red Nucleus ◽  
Wilson's Disease ◽  
Cortical Network ◽  
Advanced Technique

Wilson’s disease (WD) is a genetic disorder of copper metabolism with pathological copper accumulation in the brain and any other tissues. This article aimed to assess lesions in cerebello-thalamo-cortical network with an advanced technique of diffusion tensor imaging (DTI) in WD. 35 WD patients and 30 age- and sex-matched healthy volunteers were recruited to accept diffusion-weighted images with 15 gradient vectors and conventional magnetic resonance imaging (MRI). The DTI parameters, including fractional anisotropy (FA) and mean diffusion (MD), were calculated by diffusion kurtosis estimator software. After registration, patient groups with FA mappings and MD mappings and normal groups were compared with 3dttest and receiver-operating characteristic (ROC) curve analysis, corrected with FDR simulations (p=0.001, α=0.05, cluster size = 326). We found that the degree of FA increased in the bilateral head of the caudate nucleus (HCN), lenticular nucleus (LN), ventral thalamus, substantia nigra (SN), red nucleus (RN), right dentate nucleus (DN), and decreased in the mediodorsal thalamus and extensive white matter. The value of MD increased in HCN, LN, SN, RN, and extensive white matter. The technique of DTI provides higher sensitivity and specificity than conventional MRI to detect Wilson’s disease. Besides, lesions in the basal ganglia, thalamus, and cerebellum might disconnect the basal ganglia-thalamo-cortical circuits or dentato-rubro-thalamic (DRT) track and disrupt cerebello-thalamo-cortical network finally, which may cause clinical extrapyramidal symptoms.

Intraspinal Tumors: The Value of Diffusion Tensor Imaging (DTI) and Tractography: A Preliminary Study

2018 ◽  
Author(s):  
F. Cartes-Zumelzu ◽  
S. Ingorokva ◽  
H. Kostron ◽  
G. Feuchtner ◽  
C. Kremser ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Preliminary Study ◽  
Diffusion Tensor Imaging Dti

scholarly journals The diffusion tensor imaging (DTI) component of the NIH MRI study of normal brain development (PedsDTI)

NeuroImage ◽  
2016 ◽  
Vol 124 ◽  
pp. 1125-1130 ◽  
Author(s):  
Lindsay Walker ◽  
Lin-Ching Chang ◽  
Amritha Nayak ◽  
M. Okan Irfanoglu ◽  
Kelly N. Botteron ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Brain Development ◽  
Diffusion Tensor ◽  
Normal Brain ◽  
Mri Study ◽  
Normal Brain Development ◽  
Diffusion Tensor Imaging Dti
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