Teleost Fish as a Model System to Study Successful Regeneration of the Central Nervous System

2012 ◽  
pp. 193-233 ◽  
Author(s):  
Günther K. H. Zupanc ◽  
Ruxandra F. Sîrbulescu
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Teleost Fish ◽  
Model System ◽  
The Central Nervous System

scholarly journals 11beta-hydroxylase and aldosterone synthase expression in fetal rat hippocampal neurons

2002 ◽  
Vol 29 (3) ◽  
pp. 319-325 ◽  
Author(s):  
SM MacKenzie ◽  
M Lai ◽  
CJ Clark ◽  
R Fraser ◽  
CE Gomez-Sanchez ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Hippocampal Neurons ◽  
Primary Cultures ◽  
Local System ◽  
Model System ◽  
Biochemical Reactions ◽  
Aldosterone Synthase ◽  
Fetal Rat ◽  
The Central Nervous System

The central nervous system produces many of the enzymes responsible for corticosteroid synthesis. A model system to study the regulation of this local system would be valuable. Previously, we have shown that primary cultures of hippocampal neurons isolated from the fetal rat can perform the biochemical reactions associated with the enzymes 11beta-hydroxylase and aldosterone synthase. Here, we demonstrate directly that these enzymes are present within primary cultures of fetal rat hippocampal neurons.

Pursuit and prediction in the tracking of moving food by a teleost fish (Acanthaluteres spilomelanurus)

1975 ◽  
Vol 63 (3) ◽  
pp. 627-645
Author(s):  
B. S. Lanchester ◽  
R. F. Mark
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Teleost Fish ◽  
Constant Velocity ◽  
The Body ◽  
Retinal Images ◽  
Body Movements ◽  
Forward Movement ◽  
The Central Nervous System ◽  
Point Of Intersection

1. The path, eye and body movements of a teleost fish (the leatherjacket Acanthaluteres spilomelanurus) approaching and taking food were measured by cinematography. 2. Fixation of the food by movement of the eyes is an invariable feature of the approach. The eyes then remain aligned with the target while the body moves forward and round to bring the mouth to the food. 3. When pursuing pieces of food moving vertically at constant velocity through the water these fish normally trace out the pathway that can be calculated by assuming the fish aims constantly at the food. Predictive pathways that imply anticipation of the point of intersection with the food are not regularly seen. 4. Deviations from pursuit occur sporadically, usually in the direction of a predictive path, particularly when the fish approach falling food from below. 5. The geometry of the situation suggests that predictive paths may sometimes be generated if the alignment of eye and body during the pursuit of moving food can be delayed. In approaches from below this may be because forward movement of the fish would tend to stabilize the image of the falling food in the retina. 6. We suggest that a simple linked control system using both eye and body movements to fixate retinal images will on occasions generate predictive pathways without any need for the central nervous system to calculate them in advance.

Relative susceptibility of elements of the cerebral cortex to mechanical trauma in the rat

1971 ◽  
Vol 35 (5) ◽  
pp. 517-522 ◽  
Author(s):  
Melvin H. Epstein
Keyword(s):  
Central Nervous System ◽  
Tissue Culture ◽  
Nervous System ◽  
Cerebral Cortex ◽  
Nutrient Medium ◽  
Model System ◽  
Mechanical Trauma ◽  
Content Type ◽  
The Central Nervous System ◽  
Fine Print

✓ A model system for the study of trauma to elements of the central nervous system is described. It consists of floating samples of cortex (1 mm3) in nutrient medium. After variable amounts of trauma the cortical samples are allowed to grow in tissue culture, or their individual cytoarchitectonic layers are studied metabolically in the Cartesian diver. The results indicate that neurons are the most labile cellular elements when the cerebral cortex is exposed to mechanical trauma. The glia are the next most vulnerable to damage while the fibroblastic series are highly resistant to concussive forces.

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