MicroRNA Expression Profiling by PCR Array in 2D and 3D Differentiated Neural Culture Systems and Target Validation

2017 ◽  
pp. 43-57
Author(s):  
Lara Stevanato ◽  
Caroline Hicks ◽  
Lavaniya Thanabalasundaram ◽  
John D. Sinden
Keyword(s):  
Expression Profiling ◽  
Microrna Expression ◽  
Pcr Array ◽  
Target Validation ◽  
Culture Systems ◽  
Neural Culture ◽  
2D And 3D

MicroRNA expression profiling in Acute myeloid leukemia patients

2009 ◽  
Vol 221 (03) ◽  
Author(s):  
S Daschkey ◽  
T Haferlach ◽  
A Borkhardt ◽  
P Landgraf
Keyword(s):  
Acute Myeloid Leukemia ◽  
Expression Profiling ◽  
Myeloid Leukemia ◽  
Microrna Expression ◽  
Acute Myeloid

scholarly journals Analysis of Circulating microRNA Signatures and Preeclampsia Development

Cells ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1003
Author(s):  
Margarita L. Martinez-Fierro ◽  
Idalia Garza-Veloz
Keyword(s):  
Pregnant Women ◽  
Expression Profiling ◽  
Gene Prediction ◽  
Microrna Expression ◽  
Differentially Expressed ◽  
Control Group ◽  
Case Group ◽  
Circulating Microrna ◽  
Activated T Cells ◽  
Serum Microrna

microRNAs are important regulators of cell processes and have been proposed as potential preeclampsia biomarkers. We evaluated serum microRNA expression profiling to identify microRNAs involved in preeclampsia development. Serum microRNA expression profiling was evaluated at 12, 16, and 20 weeks of gestation (WG), and at the time of preeclampsia diagnosis. Two groups were evaluated using TaqMan low-density array plates: a control group with 18 normotensive pregnant women and a case group with 16 patients who developed preeclampsia during the follow-up period. Fifty-three circulating microRNAs were differentially expressed between groups (p < 0.05). Compared with controls, hsa-miR-628-3p showed the highest relative quantity values (at 12 WG = 7.7 and at 20 WG = 3.45) and the hsa-miRs -151a-3p and -573 remained differentially expressed from 16 to 20 WG (p < 0.05). Signaling pathways including cancer-related, axon guidance, Neurotrophin, GnRH, VEGF, and B/T cell receptor, were most commonly altered. Further target gene prediction revealed that nuclear factor of activated T-cells 5 gene was included among the transcriptional targets of preeclampsia-modulated microRNAs. Specific microRNAs including hsa-miRs -628-3p, -151a-3p, and -573 were differentially expressed in serum of pregnant women before they developed preeclampsia compared with controls and their participation in the preeclampsia development should be considered.

A meta-analysis of microRNA expression profiling studies in heart failure

2021 ◽  
Author(s):  
Alieh Gholaminejad ◽  
Nasrin Zare ◽  
Nasim Dana ◽  
Davood Shafie ◽  
Arya Mani ◽  
...  
Keyword(s):  
Heart Failure ◽  
Expression Profiling ◽  
Meta Analysis ◽  
Microrna Expression

Identification of high-risk Dukes B colorectal cancer by microRNA expression profiling: a preliminary study

2015 ◽  
Vol 17 (7) ◽  
pp. 578-588 ◽  
Author(s):  
M. I. Aslam ◽  
J. Venkatesh ◽  
J. S. Jameson ◽  
K. West ◽  
J. H. Pringle ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
High Risk ◽  
Expression Profiling ◽  
Microrna Expression ◽  
Preliminary Study

scholarly journals Phytoestrogen (Daidzein) Promotes Chondrogenic Phenotype of Human Chondrocytes in 2D and 3D Culture Systems

2017 ◽  
Vol 14 (2) ◽  
pp. 103-112 ◽  
Author(s):  
Suhaeb A. Mahmod ◽  
Simmrat Snigh ◽  
Ivan Djordjevic ◽  
Yong Mei Yee ◽  
Rohana Yusof ◽  
...  
Keyword(s):  
3D Culture ◽  
Human Chondrocytes ◽  
Culture Systems ◽  
Chondrogenic Phenotype ◽  
2D And 3D
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