Microreactor Technology as an Efficient Tool for Multicomponent Reactions

Author(s):  
Ana Cukalovic ◽  
Jean-Christophe M. R. Monbaliu ◽  
Christian V. Stevens
ChemInform ◽  
2010 ◽  
Vol 42 (2) ◽  
pp. no-no
Author(s):  
Ana Cukalovic ◽  
Jean-Christophe M. R. Monbaliu ◽  
Christian V. Stevens

2020 ◽  
Vol 3 (1) ◽  
pp. 108
Author(s):  
Erika Bálint ◽  
Nóra Popovics-Tóth ◽  
Ádám Tajti ◽  
Bettina Rávai ◽  
Kármen Emőke Szabó ◽  
...  

Organophosphorus compounds play an important role in the medicinal- or agricultural industry, and in the human body as well. Over the last years, heterocyclic phosphonates have received growing interest due to their potential biological activity. An efficient tool for the preparation of such derivatives is their synthesis via multicomponent reactions. These transformations possess several criteria of an “ideal synthesis”, such as high atom economy, fast and simple accomplishment, energy efficiency, and environmentally friendliness. A number of heterocyclic phosphonates were prepared by us utilizing multicomponent syntheses. In this proceeding, the synthesis of the diethyl (2-amino-3-cyano-4H-chromen-4-yl)phosphonate by the condensation of salicylaldehyde, malononitrile and diethyl phosphite is briefly introduced. The reaction was optimized in respect of the catalyst type, the catalyst amount, the reaction time, and the temperature.


2020 ◽  
Vol 3 (2) ◽  
pp. 58-73
Author(s):  
Vijay Bhagat ◽  
Ajaykumar Kada ◽  
Suresh Kumar

Unmanned Aerial System (UAS) is an efficient tool to bridge the gap between high expensive satellite remote sensing, manned aerial surveys, and labors time consuming conventional fieldwork techniques of data collection. UAS can provide spatial data at very fine (up to a few mm) and desirable temporal resolution. Several studies have used vegetation indices (VIs) calculated from UAS based on optical- and MSS-datasets to model the parameters of biophysical units of the Earth surface. They have used different techniques of estimations, predictions and classifications. However, these results vary according to used datasets and techniques and appear very site-specific. These existing approaches aren’t optimal and applicable for all cases and need to be tested according to sensor category and different geophysical environmental conditions for global applications. UAS remote sensing is a challenging and interesting area of research for sustainable land management.


2020 ◽  
Vol 24 (14) ◽  
pp. 1610-1642 ◽  
Author(s):  
Ahmed El-Mekabaty ◽  
Hassan A. Etman ◽  
Ahmed Mosbah ◽  
Ahmed A. Fadda

Barbituric, thiobarbituric acids and their related analogs are reactive synthons for the synthesis of drugs and biologically, and pharmaceutically active pyrimidines. The present review aimed to summarize the recent advances in the synthesis of different alkylsubstituted, fused cycles, spiro-, and binary heterocycles incorporated pyrimidine skeleton based on barbituric derivatives. In this sequence, the eco-friendly techniques under catalytic conditions were used for the diverse types of multicomponent reactions under different conditions for the synthesis of various types of heterocycles. Nano-catalysts are efficient for the synthesis of these compounds in high yields and effective catalyst reusability. The compounds are potent antibacterial, cytotoxic, xanthine oxidase inhibitory activities, and attend as urease inhibitors. The projected mechanisms for the synthesis of pyranopyrimidines, benzochromenopyrimidines, chromeno-pyranopyrimidines, spiroxyindoles, oxospiro-tricyclic furopyrimidines, pyrimidine-based monoand bicyclic pyridines were discussed. The potent and diverse biological activities for instance, antioxidant, antibacterial, cytotoxic, and xanthine oxidase inhibitory activities, as well as urease inhibitors, are specified.


2013 ◽  
Vol 17 (5) ◽  
pp. 474-490 ◽  
Author(s):  
Amit Kumar Gupta ◽  
Neetu Singh ◽  
Krishna Nand Singh

2013 ◽  
Vol 16 (10) ◽  
pp. 788-790
Author(s):  
Zinatossadat Hossaini ◽  
Samereh Seyfi ◽  
Faramarz Rostami-Charati ◽  
Mehdi Ghambarian

2014 ◽  
Vol 14 (20) ◽  
pp. 2209-2230 ◽  
Author(s):  
Angel Cores ◽  
Carlos Carbajales ◽  
Alberto Coelho

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