Recoverable, Soluble Polymer-Supported Organic Catalysts

2007 ◽  
pp. 76-96 ◽  
Author(s):  
M. Benaglia
Keyword(s):  
Soluble Polymer ◽  
Polymer Supported ◽  
Organic Catalysts

Soluble polymer-supported organocatalysts

2012 ◽  
Vol 85 (3) ◽  
pp. 493-509 ◽  
Author(s):  
Yun-Chin Yang ◽  
David E. Bergbreiter
Keyword(s):  
Transition Metal ◽  
Organic Synthesis ◽  
Metal Catalysts ◽  
Transition Metal Catalysts ◽  
Soluble Polymer ◽  
Soluble Polymers ◽  
The Past ◽  
Polymer Supports ◽  
Polymer Supported ◽  
Simple Product

Organocatalysts have been extensively studied for the past few decades as alternatives to transition-metal catalysts. Immobilizing organocatalysts on polymer supports allows easy recovery and simple product purification after a reaction. Select examples of recent reports that describe the potential advantages of using soluble polymers to prepare soluble polymer-supported organocatalysts useful in organic synthesis are reviewed.

Enantioselective Hydrolysis of Soluble Polymer-Supported Carboxylates

Synfacts ◽  
2010 ◽  
Vol 2010 (12) ◽  
pp. 1443-1443
Author(s):  
K. Matsumoto ◽  
M. Okudomi ◽  
K. Ageishi ◽  
T. Yamada ◽  
N. Chihara ◽  
...  
Keyword(s):  
Enantioselective Hydrolysis ◽  
Soluble Polymer ◽  
Polymer Supported ◽  
Hydrolysis Of

ChemInform Abstract: Highly Selective Intermolecular Heck Reaction for the Soluble Polymer Supported Synthesis of Glutamic Acid Analogues.

ChemInform ◽  
2010 ◽  
Vol 33 (12) ◽  
pp. no-no
Author(s):  
Berengere Sauvagnat ◽  
Frederic Lamaty ◽  
Rene Lazaro ◽  
Jean Martinez
Keyword(s):  
Glutamic Acid ◽  
Heck Reaction ◽  
Soluble Polymer ◽  
Polymer Supported

ChemInform Abstract: Soluble Polymer-Supported Catalysts Containing Azo Dyes.

ChemInform ◽  
2010 ◽  
Vol 33 (33) ◽  
pp. no-no
Author(s):  
David E. Bergbreiter ◽  
Philip L. Osburn ◽  
Chunmei Li
Keyword(s):  
Azo Dyes ◽  
Supported Catalysts ◽  
Soluble Polymer ◽  
Polymer Supported

Characterization of Soluble Polymer Supported Organic Molecules by Mass Spectrometry

2003 ◽  
Vol 804 ◽  
Author(s):  
C. Enjalbal ◽  
F. Lamaty ◽  
P. Ribière ◽  
S. Varray ◽  
E. Suberchicot ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Organic Molecules ◽  
Solid Phase ◽  
Combinatorial Libraries ◽  
Maldi Mass Spectrometry ◽  
Soluble Polymer ◽  
Polymer Solubility ◽  
Esi Mass Spectrometry ◽  
Polymer Supported ◽  
Phase Chemistry

ABSTRACTSyntheses carried out on soluble polymers, such as polyethylene glycol (PEG), benefit the advantages of both solution-phase and solid-phase syntheses. The choice of the reaction solvent governs the polymer solubility. Synthetic steps are conducted under homogeneous conditions whereas purifications are performed by filtration after polymer precipitation. This alternative strategy, known as liquid-phase chemistry, has been investigated to prepare combinatorial libraries.The fact that soluble polymer supported molecules are directly amenable to standard spectroscopic methods, including NMR (1H, 13C) and ESI or MALDI mass spectrometry (ElectroSpray and Matrix Assisted Laser Desorption Ionization) allows to perform to in situ reaction monitoring without the need to release the compound from the polymeric support.We report a general methodology to characterize step by step soluble polymer supported organic molecules by MALDI and ESI mass spectrometry. High throughput analyses were targeted to fullfil combinatorial chemistry requirements. Data acquisition and interpretation were automated through the design of specific experimental protocols and a data managment software. MALDI mass spectrometry was appropriate to analyze pure supported molecules whereas ESI mass spectrometry coupled to liquid chromatography was required to unravel PEG mixtures.

Soluble Polymer-Supported Methods for Combinatorial and Organic Synthesis

ChemInform ◽  
2003 ◽  
Vol 34 (29) ◽  
Author(s):  
Paul Jr. Wentworth ◽  
Carsten Spanka
Keyword(s):  
Organic Synthesis ◽  
Soluble Polymer ◽  
Polymer Supported
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