Histamine and Histamine Receptors in Allergic Dermatitis

Author(s):  
Hiroshi Ohtsu ◽  
Masahiro Seike
Author(s):  
J. S. Shruthi ◽  
N. G. Amith ◽  
P. Priya ◽  
J. K. Pramodh ◽  
T. Chandrashekar

Aural haematoma is the collection of blood or serum within the cartilage plate of the ear pinna which presents as fluctuant, fluid-filled swelling on the concave surface of one or both the pinna (Fossum, 2007). It occurs as a result of constant shaking and rubbing of ear due to otitis, ectoparasitism, ottorrhoea, foreign bodies, hypersensitivity and allergic dermatitis. This chronic irritation, constant shaking and rubbing of the ear leads to rupture of the pinnal blood vessel resulting in haematoma formation (Ahiwar et al., 2007).


Molecules ◽  
2021 ◽  
Vol 26 (6) ◽  
pp. 1778
Author(s):  
Pakhuri Mehta ◽  
Przemysław Miszta ◽  
Sławomir Filipek

The recent developments of fast reliable docking, virtual screening and other algorithms gave rise to discovery of many novel ligands of histamine receptors that could be used for treatment of allergic inflammatory disorders, central nervous system pathologies, pain, cancer and obesity. Furthermore, the pharmacological profiles of ligands clearly indicate that these receptors may be considered as targets not only for selective but also for multi-target drugs that could be used for treatment of complex disorders such as Alzheimer’s disease. Therefore, analysis of protein-ligand recognition in the binding site of histamine receptors and also other molecular targets has become a valuable tool in drug design toolkit. This review covers the period 2014–2020 in the field of theoretical investigations of histamine receptors mostly based on molecular modeling as well as the experimental characterization of novel ligands of these receptors.


2021 ◽  
Author(s):  
Katharina Hansel ◽  
Chiara Sensini ◽  
Paola Caposciutti ◽  
Rossella Marietti ◽  
Marta Tramontana ◽  
...  

2004 ◽  
Vol 335 (1) ◽  
pp. 42-49 ◽  
Author(s):  
Kathy Crane ◽  
Daw-tsun Shih

1979 ◽  
Vol 58 (3) ◽  
pp. 295-304 ◽  
Author(s):  
Jose M. Palacios ◽  
W. Scott Young ◽  
Michael J. Kuhar
Keyword(s):  

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