Key Questions for Translation of FFA Receptors: From Pharmacology to Medicines

2016 ◽  
pp. 101-131 ◽  
Author(s):  
Arthur T. Suckow ◽  
Celia P. Briscoe
Keyword(s):  
Key Questions

Accent Modification for Speakers With Indian Accents: Speech Characteristics and an Assessment Framework

2012 ◽  
Vol 19 (1) ◽  
pp. 12-20 ◽  
Author(s):  
Amee P. Shah
Keyword(s):  
United States ◽  
Asian Indian ◽  
The United States ◽  
Assessment Framework ◽  
Speech And Language ◽  
Speech Characteristics ◽  
Accent Modification ◽  
Key Questions

In this paper, I present accent-related variations unique to Asian-Indian speakers of English in the United States and identify specific speech and language features that contribute to an “Indian accent.” I present a model to answer some key questions related to assessment of Indian accents and help set a strong foundation for accent modification services.

The Day of Remembrance of the “Cursed Soldiers”: commemorative practices in contemporary Poland

2019 ◽  
pp. 269-288
Author(s):  
Anna Lagno
Keyword(s):  
Political Struggle ◽  
Parliamentary Elections ◽  
Additional State ◽  
The Law ◽  
Law And Justice ◽  
Rewriting History ◽  
Key Questions

Since 1 March 2011 Poland has marked the National Day of Remembrance of the „Cursed Soldiers” (Narodowy Dzień Pamięci “Żołnierzy Wyklętych”) — members of the anti-Communist underground in the 1940s and 1950s who tried to prevent Poland’s sovietisation and subordination to the USSR. The idea of establishing such a state memorial day was expressed in 2010 by Lech Kaczyński, the then President of Poland and one of the leaders of the Law and Justice Party (L&J). During the debates on the Bill of the National Day of Remembrance in the Sejm, the deputies of the two main opposing parties voted in favour almost unanimously and the Senate approved it without making any changes. After President Bronisław Komorowski signed it on 1 March 2011, Poland acquired an additional state holiday. In 2015, after the Law and Justice Party won both the presidential and parliamentary elections, the issue of the „cursed soldiers” turned into one of the key questions in historical policy. The „Civic Platform” party, forced to move over to the opposition benches in parliament, sounded the alarm, accusing the L&J party of rewriting history and primitivising the image of the anti-Communist underground. Thus, the memory of the “cursed soldiers” transformed from an issue that united political opponents to a topic for arguments and political struggle. The article attempts to show how the L&J party used the preservation of the memory of the “cursed soldiers” for its own political purposes, including its fight against the opposition.

When Human Rights Clash at the European Court of Human Rights

2017 ◽  
Keyword(s):  
Human Rights ◽  
Practical Relevance ◽  
Ongoing Debate ◽  
Reasonable Disagreement ◽  
European Court ◽  
Key Questions ◽  
Rights Conflicts

This book aims to answer key questions surrounding (purported) conflicts of human rights at the European Court of Human Rights. Some of these questions concern the very existence of human rights conflicts. Can human rights really conflict with one another? Or should they be interpreted in harmony with one another? Other questions relate to the resolution of genuine human rights conflicts. How should such genuine conflicts be resolved? To what extent is balancing desirable? And which understanding of balancing should be employed? Throughout the book, contributors aim to answer these questions by engaging in concerted debate on both the existence and resolution of human rights conflicts. To increase its practical relevance, the discussion is framed around leading judgments of the European Court. The book ultimately aims to suggests, through the prism of reasonable disagreement, concrete ways forward in the ongoing debate on human rights conflicts at Europe’s human rights court.

The Utility and Content of Traditional Ads

2019 ◽  
pp. 201-223
Author(s):  
Michael Franz
Keyword(s):  
Resource Allocation ◽  
New Technologies ◽  
Television Advertising ◽  
Tipping Point ◽  
Political Actors ◽  
Broadcast Television ◽  
Political Ads ◽  
Issue Content ◽  
Key Questions

This chapter focuses on traditional political ads in US elections, in particular those most often airing on broadcast television stations, investigating three key questions: Have traditional political ads reached a tipping point, as new technologies and voter targeting opportunities shift the resource allocation of campaigns? Do traditional political ads work in changing minds and mobilizing voters, and how might those opportunities for persuasion and mobilization change as media engagement diversifies? Finally, what is the issue content of traditional political ads, and how does the content vary across platforms? All told, despite fast-developing change in opportunities for political actors to reach voters, television advertising remains a critically important strategy for campaigns and their political allies.

scholarly journals Monitoring norms: a multi-disciplinary perspective

2018 ◽  
Vol 33 ◽  
Author(s):  
Mehdi Dastani ◽  
Paolo Torroni ◽  
Neil Yorke-Smith
Keyword(s):  
Artificial Intelligence ◽  
Cultural Studies ◽  
Computer Security ◽  
Social Setting ◽  
Multi Agent Systems ◽  
Agent Systems ◽  
Organizational Behaviour ◽  
Disciplinary Perspective ◽  
Multi Agent ◽  
Key Questions

AbstractThe concept of anormis found widely across fields including artificial intelligence, biology, computer security, cultural studies, economics, law, organizational behaviour and psychology. The concept is studied with different terminology and perspectives, including individual, social, legal and philosophical. If a norm is an expected behaviour in a social setting, then this article considers how it can be determined whether an individual is adhering to this expected behaviour. We call this processmonitoring, and again it is a concept known with different terminology in different fields. Monitoring of norms is foundational for processes of accountability, enforcement, regulation and sanctioning. Starting with a broad focus and narrowing to the multi-agent systems literature, this survey addresses four key questions: what is monitoring, what is monitored, who does the monitoring and how the monitoring is accomplished.

scholarly journals Key questions in the new hemophilia era: update on concomitant use of FVIII and emicizumab in hemophilia A patients with inhibitors

2021 ◽  
Vol 14 (2) ◽  
pp. 143-148
Author(s):  
Manuel Carcao ◽  
Maria Elisa Mancuso ◽  
Guy Young ◽  
Víctor Jiménez-Yuste
Keyword(s):  
Hemophilia A ◽  
Key Questions

Mental disorder and homicide: a review of epidemiological research

2000 ◽  
Vol 9 (3) ◽  
pp. 171-189 ◽  
Author(s):  
Mark Woodward ◽  
Jean Nursten ◽  
Paul Williams ◽  
Doug Badger
Keyword(s):  
Social Sciences ◽  
Mental Disorder ◽  
Epidemiological Research ◽  
Mentally Disordered ◽  
Academic Literature ◽  
Comprehensive Search ◽  
General Populations ◽  
Key Questions

SummaryObjective – This paper reviews 28 studies on the epidemiology of homicide committed by mentally disordered people, taken from recent international academic literature. Methods – The studies included were identified as part of a wider systematic review of the epidemiology of offending combined with mental disorder. The main databases searched were Embase, Medline, HealthStar, Psyclit, Mental Health Abstracts, Applied Social Sciences Index and Abstracts, and Criminology Penology and Police Science Abstracts. A comprehensive search was made for studies published since 1990, supplemented with key studies from the 1980s identified through citation tracing and personal contacts. Results – A summary is given in tabular form of the content and quality of each study. There is then discussion of the studies in eight categories: descriptive studies, studies of trends, comparative studies amongst homicide offenders, amongst prisoners and including general populations, studies of homicide of relatives, follow-up studies, and studies of recidivism. Conclusions – There is an association of homicide with mental disorder, most particularly with certain manifestations of schizophrenia, antisocial personality disorder and drug or alcohol abuse. However, the quality of epidemiological research in this area is not adequate to answer key questions, and prediction of potential for homicide remains elusive. Further research is needed.

Using a novel breathable silicone adhesive (Sil2 technology) in stoma appliances to improve peristomal skin health: answering the key questions

2021 ◽  
Vol 30 (Sup8) ◽  
pp. 19-24
Author(s):  
Fiona Le Ber
Keyword(s):  
Skin Damage ◽  
Skin Injury ◽  
Moisture Management ◽  
Silicone Adhesive ◽  
Peristomal Skin ◽  
Medical Adhesive ◽  
Key Questions ◽  
Stoma Care

Fiona Le Ber answers some of the questions that stoma care nurses may have regarding this novel silicone adhesive based technology, which helps to avoid medical adhesive related skin injury (MARSI) and moisture-associated skin damage (MASD). Whereas hydrocolloid stoma appliances absorb moisture, this has a non-absorptive method of moisture management that prevents peristomal skin becoming damp and excoriated.

scholarly journals Building a stem cell-based primate uterus

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Sophie Bergmann ◽  
Magdalena Schindler ◽  
Clara Munger ◽  
Christopher A. Penfold ◽  
Thorsten E. Boroviak
Keyword(s):  
Stem Cell ◽  
Fetal Development ◽  
Embryo Implantation ◽  
In Vitro Models ◽  
Uterine Tissue ◽  
Controlled Assembly ◽  
Uterine Cancers ◽  
Term Births ◽  
Key Questions

AbstractThe uterus is the organ for embryo implantation and fetal development. Most current models of the uterus are centred around capturing its function during later stages of pregnancy to increase the survival in pre-term births. However, in vitro models focusing on the uterine tissue itself would allow modelling of pathologies including endometriosis and uterine cancers, and open new avenues to investigate embryo implantation and human development. Motivated by these key questions, we discuss how stem cell-based uteri may be engineered from constituent cell parts, either as advanced self-organising cultures, or by controlled assembly through microfluidic and print-based technologies.

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