Reusable Components for Implementing Agent Interactions

Author(s):  
Juan M. Serrano ◽  
Sascha Ossowski ◽  
Sergio Saugar
Author(s):  
Guillaume Dubuisson Duplessis ◽  
Caroline Langlet ◽  
Chloé Clavel ◽  
Frédéric Landragin

2019 ◽  
Vol 3 (OOPSLA) ◽  
pp. 1-28 ◽  
Author(s):  
Sven Keidel ◽  
Sebastian Erdweg

2015 ◽  
Vol 44 ◽  
pp. 243-259 ◽  
Author(s):  
Salam Hajjar ◽  
Emil Dumitrescu ◽  
Laurent Pietrac ◽  
Eric Niel

2004 ◽  
Vol XXIV (3) ◽  
pp. 44-46
Author(s):  
Jeffrey R. Carter
Keyword(s):  

1980 ◽  
Vol 29 (2) ◽  
pp. 633-641 ◽  
Author(s):  
Thuang S. Lim ◽  
Juneann W. Murphy ◽  
Larry K. Cauley

Inbred CBA/J mice were used in developing a defined in vivo model for studying host-parasite relationships in cryptococcosis. Mice were infected either intranasally or intraperitoneally with 10 3 viable Cryptococcus neoformans cells. At weekly intervals over a 92-day period, C. neoformans growth profiles in the lungs, spleens, livers, and brains of the infected animals were determined. In addition, humoral and delayed-type hypersensitivity responses and cryptococcal antigen levels were assayed in these mice. Intranasally infected mice developed strong delayed-type hypersensitivity reactions in response to cryptococcal culture filtrate (CneF) antigen, and there was good correlation between acquisition of delayed-type hypersensitivity and the reduction of C. neoformans cell numbers in infected tissues. In contrast, intraperitoneally infected mice displayed greater numbers of C. neoformans cells in tissues and had somewhat suppressed delayed-type hypersensitivity responses to CneF antigen. Anticryptococcal antibodies were not detected in intranasally or intraperitoneally infected mice, but cryptococcal polysaccharide antigen titers were relatively high in both groups. The transfer of sensitized spleen cells from intranasally infected mice to syngeneic naive recipient mice resulted in the transfer of delayed-type hypersensitivity responsiveness to cryptococcal antigen in the recipients. The intranasally induced infection in mice was similar to the naturally acquired infection in humans; therefore we are proposing that this murine-cryptococcosis model would be useful in gaining a greater understanding of host-etiological agent relationships in this disease.


Micromachines ◽  
2019 ◽  
Vol 10 (10) ◽  
pp. 707 ◽  
Author(s):  
Benjamin Gursky ◽  
Sebastian Bütefisch ◽  
Monika Leester-Schädel ◽  
Kangqi Li ◽  
Barbara Matheis ◽  
...  

A new design for a single-use disposable pneumatic microgripper is presented in this paper. It enables very cost-effective batch microfabrication in SU-8 with a single lithography mask by shifting manufacturing complexity into reusable components. An optically readable force sensor with potential to be used in a feedback loop has been integrated in order to enable gripping with a controlled force. The sensors are first examined separately from the gripper and exhibit good linearity. The gripper function utilizes the disposable gripper element together with a reusable gripper fixture. During experiments, the pneumatically actuated microgripper can vary the gripping force within a range of a few mN (up to 5.7 mN was observed). This microgripper is planned to be used in a liquid environment for gripping larger aggregates of cells in combination with the patch clamp technique. This approach will allow Langerhans islets suspended in an electrolyte solution to be grasped and held during electrophysiological measurements without cell damage.


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