A Toxicokinetic Study of Inhaled Ethylene Glycol Ethyl Ether Acetate and Validation of a Physiologically Based Pharmacokinetic Model for Rat and Human

Michael L. Gargas; Tipton R. Tyler; Lisa M. Sweeney; Richard A. Corley; Karl K. Weitz; Terryl J. Mast; Dennis J. Paustenbach; Sean M. Hays

doi:10.1006/taap.2000.8927

A Toxicokinetic Study of Inhaled Ethylene Glycol Ethyl Ether Acetate and Validation of a Physiologically Based Pharmacokinetic Model for Rat and Human

Toxicology and Applied Pharmacology ◽

10.1006/taap.2000.8927 ◽

2000 ◽

Vol 165 (1) ◽

pp. 63-73 ◽

Cited By ~ 31

Author(s):

Michael L. Gargas ◽

Tipton R. Tyler ◽

Lisa M. Sweeney ◽

Richard A. Corley ◽

Karl K. Weitz ◽

...

Keyword(s):

Ethylene Glycol ◽

Ethyl Ether ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Glycol Ethyl Ether

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A Toxicokinetic Study of Inhaled Ethylene Glycol Monomethyl Ether (2-ME) and Validation of a Physiologically Based Pharmacokinetic Model for the Pregnant Rat and Human

Toxicology and Applied Pharmacology ◽

10.1006/taap.2000.8928 ◽

2000 ◽

Vol 165 (1) ◽

pp. 53-62 ◽

Cited By ~ 36

Author(s):

Michael L. Gargas ◽

Tipton R. Tyler ◽

Lisa M. Sweeney ◽

Richard A. Corley ◽

Karl K. Weitz ◽

...

Keyword(s):

Ethylene Glycol ◽

Pharmacokinetic Model ◽

Monomethyl Ether ◽

Physiologically Based Pharmacokinetic Model ◽

Ethylene Glycol Monomethyl Ether ◽

Glycol Monomethyl Ether ◽

Pregnant Rat ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Development of a Physiologically Based Pharmacokinetic Model for Ethylene Glycol and Its Metabolite, Glycolic Acid, in Rats and Humans

Toxicological Sciences ◽

10.1093/toxsci/kfi119 ◽

2005 ◽

Vol 85 (1) ◽

pp. 476-490 ◽

Cited By ~ 52

Author(s):

R. A. Corley ◽

M. J. Bartels ◽

E. W. Carney ◽

K. K. Weitz ◽

J. J. Soelberg ◽

...

Keyword(s):

Ethylene Glycol ◽

Glycolic Acid ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically based pharmacokinetic model development for trazodone: application to paediatric dose projection

10.26226/morressier.5971be87d462b80290b534f2 ◽

2017 ◽

Author(s):

F. Calisti

Keyword(s):

Pharmacokinetic Model ◽

Model Development ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Paediatric Dose

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Risk Assessment of Perfluorooctane Sulfonate (PFOS) using Dynamic Age Dependent Physiologically based Pharmacokinetic Model (PBPK) across human lifetime

Environmental Research ◽

10.1016/j.envres.2021.111287 ◽

2021 ◽

pp. 111287

Author(s):

Deepika Deepika ◽

Raju Prasad Sharma ◽

Marta Schuhmacher ◽

Vikas Kumar

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Perfluorooctane Sulfonate ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Age Dependent

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Human risk assessment of di-isobutyl phthalate through the application of a developed physiologically based pharmacokinetic model of di-isobutyl phthalate and its major metabolite mono-isobutyl phthalate

Archives of Toxicology ◽

10.1007/s00204-021-03057-5 ◽

2021 ◽

Author(s):

Seung-Hyun Jeong ◽

Ji-Hun Jang ◽

Hea-Young Cho ◽

Yong-Bok Lee

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Major Metabolite ◽

Physiologically Based Pharmacokinetic Model ◽

Human Risk Assessment ◽

Human Risk ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically‐Based Pharmacokinetic Model for Alectinib, Ruxolitinib, and Panobinostat in The Presence of Cancer, Renal Impairment, and Hepatic Impairment

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2282 ◽

2021 ◽

Author(s):

Mo'tasem M. Alsmadi

Keyword(s):

Renal Impairment ◽

Hepatic Impairment ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Development of a Physiologically-Based Pharmacokinetic Model for Perchloroethylene Using Tissue Concentration-Time Data

Toxicology and Applied Pharmacology ◽

10.1006/taap.1994.1179 ◽

1994 ◽

Vol 128 (1) ◽

pp. 50-59 ◽

Cited By ~ 15

Author(s):

C.E. Dallas ◽

X.M. Chen ◽

K. Obarr ◽

S. Muralidhara ◽

P. Varkonyi ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Tissue Concentration ◽

Physiologically Based Pharmacokinetic Model ◽

Time Data ◽

Physiologically Based Pharmacokinetic ◽

Concentration Time ◽

Physiologically Based

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Development of a Physiologically Based Pharmacokinetic Model for Estradiol in Rats and Humans: A Biologically Motivated Quantitative Framework for Evaluating Responses to Estradiol and Other Endocrine-Active Compounds

Toxicological Sciences ◽

10.1093/toxsci/69.1.60 ◽

2002 ◽

Vol 69 (1) ◽

pp. 60-78 ◽

Cited By ~ 37

Author(s):

D. R. Plowchalk

Keyword(s):

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Active Compounds ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Analysis of the Disposition of a Novel p38 MAPK Inhibitor, AKP-001, and Its Metabolites in Rats with a Simple Physiologically Based Pharmacokinetic Model

Drug Metabolism and Disposition ◽

10.1124/dmd.114.060046 ◽

2014 ◽

Vol 43 (2) ◽

pp. 217-226 ◽

Cited By ~ 3

Author(s):

Kazuhiko Shirota ◽

Makoto Kaneko ◽

Makoto Sasaki ◽

Kouichi Minato ◽

Akira Fujikata ◽

...

Keyword(s):

P38 Mapk ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

P38 Mapk Inhibitor ◽

Mapk Inhibitor

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Development and Application of a Multiroute Physiologically Based Pharmacokinetic Model for Oxytetracycline in Dogs and Humans

Journal of Pharmaceutical Sciences ◽

10.1002/jps.24244 ◽

2015 ◽

Vol 104 (1) ◽

pp. 233-243 ◽

Cited By ~ 33

Author(s):

Zhoumeng Lin ◽

Mengjie Li ◽

Ronette Gehring ◽

Jim E. Riviere

Keyword(s):

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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