scholarly journals Asymptotic Approximations for the Distributions of the Multinomial Goodness-of-Fit Statistics under Local Alternatives

2002 ◽  
Vol 81 (2) ◽  
pp. 335-359 ◽  
Author(s):  
Nobuhiro Taneichi ◽  
Yuri Sekiya ◽  
Akio Suzukawa
Keyword(s):  
Goodness Of Fit ◽  
Asymptotic Approximations ◽  
Local Alternatives ◽  
Fit Statistics

scholarly journals Using Ultrasound and Inflammation to Improve Prediction of Ischemic Stroke: A Secondary Analysis of the Multi-Ethnic Study of Atherosclerosis

2021 ◽  
pp. 37-43
Author(s):  
Hediyeh Baradaran ◽  
Alen Delic ◽  
Ka-Ho Wong ◽  
Nazanin Sheibani ◽  
Matthew Alexander ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Goodness Of Fit ◽  
Primary Outcome ◽  
Stroke Risk ◽  
Secondary Analysis ◽  
Predictor Variables ◽  
Baseline Model ◽  
Fit Statistics ◽  
Ischemic Stroke Risk

Introduction: Current ischemic stroke risk prediction is primarily based on clinical factors, rather than imaging or laboratory markers. We examined the relationship between baseline ultrasound and inflammation measurements and subsequent primary ischemic stroke risk. Methods: In this secondary analysis of the Multi-Ethnic Study of Atherosclerosis (MESA), the primary outcome is the incident ischemic stroke during follow-up. The predictor variables are 9 carotid ultrasound-derived measurements and 6 serum inflammation measurements from the baseline study visit. We fit Cox regression models to the outcome of ischemic stroke. The baseline model included patient age, hypertension, diabetes, total cholesterol, smoking, and systolic blood pressure. Goodness-of-fit statistics were assessed to compare the baseline model to a model with ultrasound and inflammation predictor variables that remained significant when added to the baseline model. Results: We included 5,918 participants. The primary outcome of ischemic stroke was seen in 105 patients with a mean follow-up time of 7.7 years. In the Cox models, we found that carotid distensibility (CD), carotid stenosis (CS), and serum interleukin-6 (IL-6) were associated with incident stroke. Adding tertiles of CD, IL-6, and categories of CS to a baseline model that included traditional clinical vascular risk factors resulted in a better model fit than traditional risk factors alone as indicated by goodness-of-fit statistics. Conclusions: In a multiethnic cohort of patients without cerebrovascular disease at baseline, we found that CD, CS, and IL-6 helped predict the occurrence of primary ischemic stroke. Future research could evaluate if these basic ultrasound and serum measurements have implications for primary prevention efforts or clinical trial inclusion criteria.

scholarly journals Models for Tree Taper Form: The Gompertz and Vasicek Diffusion Processes Framework

Symmetry ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 80 ◽  
Author(s):  
Martynas Narmontas ◽  
Petras Rupšys ◽  
Edmundas Petrauskas
Keyword(s):  
Goodness Of Fit ◽  
Diffusion Processes ◽  
Parameters Estimation ◽  
Data Set ◽  
Mixed Effect ◽  
Fit Statistics ◽  
Stem Taper ◽  
Longitudinal Measurements ◽  
High Level ◽  
Taper Models

In this work, we employ stochastic differential equations (SDEs) to model tree stem taper. SDE stem taper models have some theoretical advantages over the commonly employed regression-based stem taper modeling techniques, as SDE models have both simple analytic forms and a high level of accuracy. We perform fixed- and mixed-effect parameters estimation for the stem taper models by developing an approximated maximum likelihood procedure and using a data set of longitudinal measurements from 319 mountain pine trees. The symmetric Vasicek- and asymmetric Gompertz-type diffusion processes used adequately describe stem taper evolution. The proposed SDE stem taper models are compared to four regression stem taper equations and four volume equations. Overall, the best goodness-of-fit statistics are produced by the mixed-effect parameters SDEs stem taper models. All results are obtained in the Maple computer algebra system.

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