Developmental Effects of Testosterone on Behavior in Male and Female Green Anoles (Anolis carolinensis)

2001 ◽  
Vol 39 (2) ◽  
pp. 131-143 ◽  
Author(s):  
Matthew B Lovern ◽  
F.M.Anne McNabb ◽  
Thomas A Jenssen
Keyword(s):  
Anolis Carolinensis ◽  
Male And Female ◽  
Developmental Effects

scholarly journals Developmental Effects of Prenatal Cocaine Exposure on 5-HT1A Receptors in Male and Female Rat Offspring

2002 ◽  
Vol 24 (6) ◽  
pp. 522-530 ◽  
Author(s):  
Josephine M. Johns ◽  
Deborah A. Lubin ◽  
Jeffrey A. Lieberman ◽  
Jean M. Lauder
Keyword(s):  
Female Rat ◽  
Cocaine Exposure ◽  
Prenatal Cocaine Exposure ◽  
Male And Female ◽  
Rat Offspring ◽  
Developmental Effects ◽  
Prenatal Cocaine

scholarly journals An Evaluation of the Reproductive and Developmental Effects of Tara Gum in Rats

1993 ◽  
Vol 12 (1) ◽  
pp. 91-97 ◽  
Author(s):  
Joseph F. Borzelleca ◽  
John L. Egle
Keyword(s):  
Adverse Effects ◽  
Reproductive Performance ◽  
Female Rats ◽  
Male And Female ◽  
Dietary Level ◽  
Developmental Effects ◽  
Reproduction Study ◽  
Teratogenic Potential ◽  
Successive Generations ◽  
Mated Female

In a multigeneration reproduction study, tara gum or α-cellulose was administered to male and female Charles River CD rats as a dietary admixture at levels of 5% (50,000 ppm) through 3 successive generations. All matings consisted of 10 males and 20 females per group. All litters were maintained until they were at least 21 days old (end of lactation). Fertility was generally high, and there were no consistent, statistically significant, compound-related adverse effects on any of the parameters evaluated. It is concluded that tara gum, fed at a dietary level of 5% for 3 successive generations, did not adversely affect reproductive performance. In a study designed to assess embryotoxicity and teratogenicity, tara gum was administered as a dietary admixture to mated female rats at levels of 12,500,25,000, and 50,000 ppm from days 6 to 16 postcoitum. No deaths occurred and no compound-related signs or symptoms were observed. Necropsy findings were negative. Examination of fetuses yielded no evidence of embryonic and/or teratogenic potential of tara gum.

Sequential alternation of offspring sex from successive eggs by female green anoles, Anolis carolinensis

2002 ◽  
Vol 80 (1) ◽  
pp. 77-82 ◽  
Author(s):  
Matthew B Lovern ◽  
Kelly M Passek
Keyword(s):  
Breeding Season ◽  
Sex Ratios ◽  
Female Offspring ◽  
Anolis Carolinensis ◽  
Sequential Alternation ◽  
Male And Female ◽  
Hormone Levels ◽  
Maternal Size ◽  
Offspring Production ◽  
Offspring Sex

We examined the relationships between maternal size, breeding season stage, and offspring sex at hatching for the oviparous lizard Anolis carolinensis. Specifically, we tested two hypotheses: (1) large females produce offspring with male-biased sex ratios and small females produce offspring with female-biased sex ratios; and (2) females, regardless of size, produce offspring with male-biased sex ratios early in the breeding season and female-biased sex ratios late in the breeding season. We found no support for either hypothesis. Rather, we found that individual females of all sizes and throughout the breeding season alternated offspring sex of sequentially laid eggs. Because female anoles also alternate the ovary that produces successive eggs, we tested a third hypothesis: females produce eggs of only one sex with each ovary. Both palpation to track which ovary produced which eggs, and unilateral ovariectomies, leaving females with only one functioning ovary, failed to support this hypothesis. Regardless of whether an ovary was removed, females were capable of producing both male and female offspring from either ovary. To account for this and potentially other unusual patterns of offspring production, we provide evidence that maternal hormone levels around the time of fertilization may affect offspring sex.

About substantiation of the national inventory of hazardous substances posing adverse developmental effects via lactation

2016 ◽  
pp. 2-12
Author(s):  
Kh. Kh. Khamidulina ◽  
E. V. Dorofeeva
Keyword(s):  
Adverse Effects ◽  
Sexual Function ◽  
Reproductive System ◽  
Hazardous Substances ◽  
Female Sexual Function ◽  
Male And Female ◽  
Chemical Substances ◽  
National Inventory ◽  
Developmental Effects ◽  
Hazard Classification

The international hazard classification for chemical substances and mixtures affecting the reproductive system covers also adverse developmental effects via lactation, along with assessment of their adverse effects on the male and female sexual function and fertility. Toxicological characteristics are reported that present hazard to breastfed children and are regulated at the domestic and international levels.

The Clinical, Roentgenological and Morphological Effects of an Acute Exposure of Phosgene on the Lungs of Dogs

1971 ◽  
Vol 29 ◽  
pp. 236-237
Author(s):  
R. F. Bils ◽  
W. F. Diller ◽  
F. Huth
Keyword(s):  
Latent Period ◽  
Chemical Industry ◽  
Toxic Substance ◽  
Lung Edema ◽  
X Rays ◽  
Beagle Dogs ◽  
Male And Female ◽  
Morphological Alterations ◽  
Before And After ◽  
Electron Microscopes

Phosgene still plays an important role as a toxic substance in the chemical industry. Thiess (1968) recently reported observations on numerous cases of phosgene poisoning. A serious difficulty in the clinical handling of phosgene poisoning cases is a relatively long latent period, up to 12 hours, with no obvious signs of severity. At about 12 hours heavy lung edema appears suddenly, however changes can be seen in routine X-rays taken after only a few hours' exposure (Diller et al., 1969). This study was undertaken to correlate these early changes seen by the roengenologist with morphological alterations in the lungs seen in the'light and electron microscopes.Forty-two adult male and female Beagle dogs were selected for these exposure experiments. Treated animals were exposed to 94.5-107-5 ppm phosgene for 10 min. in a 15 m3 chamber. Roentgenograms were made of the thorax of each animal before and after exposure, up to 24 hrs.

Ultrastructural investigation of spontaneous pituitary gonadotroph cell adenomas in aging Sprague-Dawley rats

1983 ◽  
Vol 41 ◽  
pp. 702-703
Author(s):  
D. J. McComb ◽  
J. Beri ◽  
F. Zak ◽  
K. Kovacs
Keyword(s):  
Electron Microscopy ◽  
Animal Model ◽  
Epoxy Resin ◽  
Immunoelectron Microscopy ◽  
Tumor Type ◽  
Gonadal Function ◽  
Sprague Dawley ◽  
Male And Female ◽  
Reticulin Fibers ◽  
Sprague Dawley Rats

Gonadotroph cell adenomas of the pituitary are infrequent in human patients and are not invariably associated with altered gonadal function. To date, no animal model of this tumor type exists. Herein, we describe spontaneous gonadotroph cell adenomas in old male and female Sprague-Dawley rats by histology, immunocytology and electron microscopy.The material consisted of the pituitaries of 27 male and 38 female Sprague Dawley rats, all 26 months of age or older, removed at routine autopsy. Sections of formal in-fixed, paraffin-embedded tissue were stained with hematoxylin-phloxine-saffron (HPS), the PAS method and the Gordon-Sweet technique for the demonstration of reticulin fibers. For immunostaining, sections were exposed to anti-rat β-LH, anti-ratβ-TSH, anti-rat PRL, anti-rat GH and anti-rat ACTH 1-39. For electron microscopy, tissue was fixed in 2.5% glutaraldehyde, postfixed in 1% OsO4 and embedded in epoxy-resin. Tissue fixed in 10% formalin, embedded in epoxy resin without osmification, was used for immunoelectron microscopy.

Quantitative ultrastructural reconstruction of small regions within large volumes by correlative light and high voltage electron microscopy of serial 0.25-0.50 μm sections

1987 ◽  
Vol 45 ◽  
pp. 578-581
Author(s):  
Conly L. Rieder ◽  
Frederick J. Miller ◽  
Edwin Davison ◽  
Samuel S. Bowser ◽  
Kirsten Lewis ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
High Voltage ◽  
Mitotic Spindle ◽  
Meiotic Spindle ◽  
High Voltage Electron Microscopy ◽  
Male And Female ◽  
Voltage Electron ◽  
High Voltage Electron ◽  
Differential Stability ◽  
Sperm Aster

In this abstract we Illustrate how same-section correlative light and high voltage electron microscopy (HVEM) of serial 0.25-0.50-μm sections can answer questions which are difficult to approach by EM of 60-100 nm sections.Starfish (Pisaster and Asterlas) eggs are fertilized at meiosis I when the oocyte contains two maternal centrosomes (e.g., asters) which form the poles of the first meiotic spindle. Immediately after fertilization a sperm aster is assembled in the vicinity of the male pronucleus and persists throughout meiosis. At syngamy the sperm aster splits to form the poles of the first mitotic spindle. During this time the functional and replicative properties of the maternal centrosome, inherited from the last meiotic division, are lost. The basis for this differential stability, of male and female centrosomes in the same cytoplasm, is a mystery.

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