Divergent Effects of Ovarian Steroids on Neuronal Survival during Experimental Allergic Encephalitis in Lewis Rats

2001 ◽  
Vol 171 (2) ◽  
pp. 272-284 ◽  
Author(s):  
G.E. Hoffman ◽  
W.W. Le ◽  
A.Z. Murphy ◽  
C.L. Koski
Keyword(s):  
Neuronal Survival ◽  
Lewis Rats ◽  
Ovarian Steroids ◽  
Experimental Allergic Encephalitis ◽  
Experimental Allergic

scholarly journals Treatment of Experimental Allergic Neuritis With Prednisolone

1987 ◽  
Vol 14 (1) ◽  
pp. 46-49 ◽  
Author(s):  
T.E. Feasby ◽  
J.J. Gilbert ◽  
A.F. Hahn ◽  
D.S. Lovgren
Keyword(s):  
Microscopic Examination ◽  
Severe Disease ◽  
Clinical Signs ◽  
Clinical Disease ◽  
Rapid Recovery ◽  
Experimental Allergic Neuritis ◽  
Nerve Roots ◽  
Lewis Rats ◽  
Experimental Allergic ◽  
Allergic Neuritis

Abstract:Experimental allergic neuritis (EAN) in Lewis rats was treated with prednisolone given prophylactically or therapeutically. Rats treated from the time of immunization with myelin or after the establishment of clinical disease improved more rapidly than controls. Treatment at the onset of clinical signs resulted in less severe disease and more rapid recovery. Rats treated just prior to the onset of clinical signs (day 10) did not develop significant clinical disease and appeared to have less inflammation in their nerves and nerve roots on microscopic examination.

Amelioration of experimental allergic encephalomyelitis in Lewis rats by lovastatin

1999 ◽  
Vol 269 (2) ◽  
pp. 71-74 ◽  
Author(s):  
Romesh Stanislaus ◽  
Kalipada Pahan ◽  
Avtar K. Singh ◽  
Inderjit Singh
Keyword(s):  
Experimental Allergic Encephalomyelitis ◽  
Allergic Encephalomyelitis ◽  
Lewis Rats ◽  
Experimental Allergic

scholarly journals Transfer of experimental allergic encephalomyelitis in Lewis rats using supernates of incubated sensitized lymph node cells.

1977 ◽  
Vol 145 (5) ◽  
pp. 1405-1410 ◽  
Author(s):  
C C Whitacre ◽  
P Y Paterson
Keyword(s):  
Spinal Cord ◽  
Lymph Node ◽  
Guinea Pig ◽  
Experimental Allergic Encephalomyelitis ◽  
Nervous Tissue ◽  
Allergic Encephalomyelitis ◽  
Lewis Rats ◽  
Transfer Activity ◽  
Lymph Node Cells ◽  
Experimental Allergic

Supernates derived from incubated lymph node cells of Lewis rats sensitized to guinea pig spinal cord-Freund's adjuvant transfer experimental allergic encephalomyelitis (EAE) to syngeneic recipients. EAE supernatant transfer activity (EAE-STA) is not demonstrable in supernates derived from LNC of control donors not sensitized to nervous tissue. After addition of brain antigen to active supernates, EAE-STA is not longer demonstrable.

Sign in / Sign up

Export Citation Format

Share Document