scholarly journals Calcium-Independent, Meiotic Spindle-Dependent Metaphase-to-Interphase Transition in Phorbol Ester-Treated Mouse Eggs

1995 ◽  
Vol 171 (1) ◽  
pp. 111-122 ◽  
Author(s):  
Ruth M. Moses ◽  
Douglas Kline
Keyword(s):  
Phorbol Ester ◽  
Treated Mouse ◽  
Meiotic Spindle ◽  
Mouse Eggs

cDNA cloning of a 8-lipoxygenase and a novel epidermis-type lipoxygenase from phorbol ester-treated mouse skin

1998 ◽  
Vol 1391 (1) ◽  
pp. 7-12 ◽  
Author(s):  
Peter Krieg ◽  
Andreas Kinzig ◽  
Markus Heidt ◽  
Friedrich Marks ◽  
Gerhard Fürstenberger
Keyword(s):  
Cdna Cloning ◽  
Phorbol Ester ◽  
Mouse Skin ◽  
Treated Mouse

Cytogenetic analysis of first cleavage fertilized mouse eggs following in vivo exposure to ethanol shortly before and at the time of conception

Development ◽  
1987 ◽  
Vol 100 (3) ◽  
pp. 441-448
Author(s):  
G.T. O'Neill ◽  
M.H. Kaufman
Keyword(s):  
Meiotic Division ◽  
Small Proportion ◽  
Cytogenetic Analysis ◽  
Chromosome Complement ◽  
Indirect Evidence ◽  
Chromosome Constitution ◽  
Meiotic Spindle ◽  
Dilute Solution ◽  
Mouse Eggs

In this study, the chromosome constitution of mouse eggs exposed in vivo to a dilute solution of ethanol during specific stages of the first and second meiotic divisions was determined at the first cleavage mitosis. Exposure to ethanol prior to the completion of the second meiotic division induced an incidence (7–10%) of aneuploidy involving only one chromosome in 98% of malsegregation events. This investigation provides indirect evidence that ethanol may induce aneuploidy by disrupting the functioning of the meiotic spindle. Karyological analyses of chromosome spreads prepared at the first cleavage metaphase suggest that only a small proportion of the total chromosome complement may be induced to undergo malsegregation.

scholarly journals Activation of erbB2 and c-src in phorbol ester-treated mouse epidermis: possible role in mouse skin tumor promotion

Oncogene ◽  
1997 ◽  
Vol 14 (12) ◽  
pp. 1435-1444 ◽  
Author(s):  
Wenjuan Xian ◽  
Michael P Rosenberg ◽  
John DiGiovanni
Keyword(s):  
Phorbol Ester ◽  
Mouse Skin ◽  
Tumor Promotion ◽  
Treated Mouse ◽  
Skin Tumor ◽  
Mouse Epidermis
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