scholarly journals SpGCF1, a Sea Urchin Embryo DNA-Binding Protein, Exists as Five Nested Variants Encoded by a Single mRNA

1995 ◽  
Vol 169 (2) ◽  
pp. 713-727 ◽  
Author(s):  
Robert W. Zeller ◽  
James A. Coffman ◽  
Michael G. Harrington ◽  
Roy J. Britten ◽  
Eric H. Davidson
Keyword(s):  
Dna Binding ◽  
Sea Urchin ◽  
Binding Protein ◽  
Dna Binding Protein ◽  
Sea Urchin Embryo

scholarly journals SpZ12-1, a negative regulator required for spatial control of the territory-specific CyIIIa gene in the sea urchin embryo

Development ◽  
1995 ◽  
Vol 121 (4) ◽  
pp. 1111-1122 ◽  
Author(s):  
D.G. Wang ◽  
C.V. Kirchhamer ◽  
R.J. Britten ◽  
E.H. Davidson
Keyword(s):  
Dna Binding ◽  
Sea Urchin ◽  
Fusion Gene ◽  
Binding Protein ◽  
Regulatory Element ◽  
Regulatory Region ◽  
Dna Binding Protein ◽  
Nuclear Extract ◽  
Negative Regulator ◽  
Expression Library

The CyIIIa cytoskeletal actin gene of the sea urchin Strongylocentrotus purpuratus is activated in late cleavage and expressed exclusively in the aboral ectoderm territory of the embryo. Previous gene transfer studies defined a 2.3 kb cis-regulatory region that is necessary and sufficient for correct temporal and spatial expression of a CyIIIa.CAT fusion gene. In this paper, a negative regulatory element within this region was identified that is required for repression of the CyIIIa gene in skeletogenic mesenchyme cells. The repression mediated by this regulatory element takes place after initial territorial specification. A cDNA clone encoding a DNA-binding protein with twelve Zn fingers (SpZ12-1) was isolated by probing an expression library with this cis-element. Deletion analysis of the SpZ12-1 protein confirmed that a DNA-binding domain is located within the Zn finger region. SpZ12-1 is the only DNA-binding protein in embryo nuclear extract that interacts with the specific cis-target sites required for repression of CyIIIa.CAT in skeletogenic mesenchyme and is likely to be the trans factor that mediates this repression.

scholarly journals A new G-stretch-DNA-binding protein, Unichrom, displays cell-cycle-dependent expression in sea urchin embryos

2004 ◽  
Vol 46 (4) ◽  
pp. 335-341 ◽  
Author(s):  
Kosho Moritani ◽  
Hideki Tagashira ◽  
Taishin Shimotori ◽  
Naoaki Sakamoto ◽  
Shin Tanaka ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Dna Binding ◽  
Sea Urchin ◽  
Binding Protein ◽  
Dna Binding Protein ◽  
Sea Urchin Embryos ◽  
Cycle Dependent

scholarly journals Cloning and characterisation of mtDBP, a DNA-binding protein which binds two distinct regions of sea urchin mitochondrial DNA

1999 ◽  
Vol 27 (8) ◽  
pp. 1890-1899 ◽  
Author(s):  
P. L. Polosa ◽  
M. Roberti ◽  
C. Musicco ◽  
M. N. Gadaleta ◽  
E. Quagliariello ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Dna Binding ◽  
Sea Urchin ◽  
Binding Protein ◽  
Dna Binding Protein

The DNA-binding protein YB-1 is a direct MYCN target and influences repair and resistance in neuroblastoma cell lines

2010 ◽  
Vol 222 (03) ◽  
Author(s):  
S Degen ◽  
S Kuhfittig-Kulle ◽  
JH Schulte ◽  
F Westermann ◽  
A Schramm ◽  
...  
Keyword(s):  
Dna Binding ◽  
Cell Lines ◽  
Binding Protein ◽  
Neuroblastoma Cell ◽  
Dna Binding Protein ◽  
Neuroblastoma Cell Lines
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