The Role of Inducible 70-kDa Heat Shock Protein in Cell Cycle Control, Differentiation, and Apoptotic Cell Death of the Human Myeloid Leukemic HL-60 Cells

1998 ◽  
Vol 187 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Hyun-Jeong Kwak ◽  
Chang-Duk Jun ◽  
Hyun-Ock Pae ◽  
Ji-Chang Yoo ◽  
Young-Chul Park ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Death ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Apoptotic Cell ◽  
Cell Cycle Control ◽  
Apoptotic Cell Death

Heat shock protein 60 from Klebsiella pneumoniae protects mononuclear cells from apoptotic cell death induced by dexamethasone

2011 ◽  
Vol 51 (5) ◽  
pp. 352-359 ◽  
Author(s):  
Yolanda Ortega-Ortega ◽  
Ethel Awilda García-Latorre ◽  
Ruth Angélica Lezama ◽  
Julieta Luna-Herrera ◽  
Armando Vega-López ◽  
...  
Keyword(s):  
Cell Death ◽  
Heat Shock ◽  
Klebsiella Pneumoniae ◽  
Heat Shock Protein ◽  
Mononuclear Cells ◽  
Apoptotic Cell ◽  
Apoptotic Cell Death ◽  
Heat Shock Protein 60

Preventing apoptotic cell death by a novel small heat shock protein

2007 ◽  
Vol 86 (3) ◽  
pp. 161-171 ◽  
Author(s):  
Szabolcs Bellyei ◽  
Andras Szigeti ◽  
Eva Pozsgai ◽  
Arpad Boronkai ◽  
Eva Gomori ◽  
...  
Keyword(s):  
Cell Death ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Apoptotic Cell ◽  
Small Heat Shock Protein ◽  
Apoptotic Cell Death

Heat Shock Protein 27 Protects Lung Epithelial Cells From Hyperoxia-Induced Apoptotic Cell Death

2009 ◽  
Vol 65 (3) ◽  
pp. 328-333 ◽  
Author(s):  
Lei Shao ◽  
Ricardo E Perez ◽  
William T Gerthoffer ◽  
William E Truog ◽  
Dong Xu
Keyword(s):  
Cell Death ◽  
Heat Shock ◽  
Epithelial Cells ◽  
Heat Shock Protein ◽  
Apoptotic Cell ◽  
Heat Shock Protein 27 ◽  
Apoptotic Cell Death ◽  
Lung Epithelial Cells ◽  
Lung Epithelial

Thiopental protects human neuroblastoma cells from apoptotic cell death — Potential role of heat shock protein 70

Life Sciences ◽  
2015 ◽  
Vol 139 ◽  
pp. 40-45 ◽  
Author(s):  
Martin Roesslein ◽  
Christian Froehlich ◽  
Verena Miltenberger ◽  
Felix Ulbrich ◽  
Ulrich Goebel ◽  
...  
Keyword(s):  
Cell Death ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Heat Shock Protein 70 ◽  
Potential Role ◽  
Apoptotic Cell ◽  
Neuroblastoma Cells ◽  
Human Neuroblastoma Cells ◽  
Human Neuroblastoma

scholarly journals Transcriptome Analysis Reveals HgCl2 Induces Apoptotic Cell Death in Human Lung Carcinoma H1299 Cells through Caspase-3-Independent Pathway

2021 ◽  
Vol 22 (4) ◽  
pp. 2006
Author(s):  
Mi Jin Kim ◽  
Jinhong Park ◽  
Jinho Kim ◽  
Ji-Young Kim ◽  
Mi-Jin An ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Death ◽  
Transcriptome Analysis ◽  
Caspase 3 ◽  
Apoptotic Cell ◽  
Expression Patterns ◽  
Nitrogen Compound ◽  
Apoptotic Cell Death ◽  
Mercury Chloride ◽  
Rna Seq

Mercury is one of the detrimental toxicants that can be found in the environment and exists naturally in different forms; inorganic and organic. Human exposure to inorganic mercury, such as mercury chloride, occurs through air pollution, absorption of food or water, and personal care products. This study aimed to investigate the effect of HgCl2 on cell viability, cell cycle, apoptotic pathway, and alters of the transcriptome profiles in human non-small cell lung cancer cells, H1299. Our data show that HgCl2 treatment causes inhibition of cell growth via cell cycle arrest at G0/G1- and S-phase. In addition, HgCl2 induces apoptotic cell death through the caspase-3-independent pathway. Comprehensive transcriptome analysis using RNA-seq indicated that cellular nitrogen compound metabolic process, cellular metabolism, and translation for biological processes-related gene sets were significantly up- and downregulated by HgCl2 treatment. Interestingly, comparative gene expression patterns by RNA-seq indicated that mitochondrial ribosomal proteins were markedly altered by low-dose of HgCl2 treatment. Altogether, these data show that HgCl2 induces apoptotic cell death through the dysfunction of mitochondria.

Sign in / Sign up

Export Citation Format

Share Document