Coexpression of Mammalian Cytochrome P450 and Reductase inEscherichia coli

1996 ◽  
Vol 327 (2) ◽  
pp. 254-259 ◽  
Author(s):  
Jinsheng Dong ◽  
Todd D. Porter
Keyword(s):  
Cytochrome P450 ◽  
Inescherichia Coli

Recombinant Human Cytochrome P450 1B1 Expression inEscherichia coli

1998 ◽  
Vol 357 (1) ◽  
pp. 111-120 ◽  
Author(s):  
Tsutomu Shimada ◽  
Rebecca M. Wunsch ◽  
Imad H. Hanna ◽  
Thomas R. Sutter ◽  
F.Peter Guengerich ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Inescherichia Coli ◽  
Cytochrome P450 1B1 ◽  
Human Cytochrome ◽  
Expression Inescherichia Coli

Molecular evolution of a cytochrome P450 for the synthesis of potential antidepressant (2R,6R)-hydroxynorketamine

2021 ◽  
Author(s):  
Ansgar Bokel ◽  
Michael C. Hutter ◽  
Vlada B. Urlacher
Keyword(s):  
Cytochrome P450 ◽  
Molecular Evolution ◽  
Cytochrome P450 Monooxygenase ◽  
P450 Monooxygenase ◽  
Effective Synthesis

Engineered cytochrome P450 monooxygenase CYP154E1 enables the effective synthesis of the potential antidepressant (2R,6R)-hydroxynorketamine via N-demethylation and regio- and stereoselective hydroxylation of (R)-ketamine.

Comparison of mechanism-based inhibition of human cytochrome P450 2C19 by ticlopidine, clopidogrel, and prasugrel

Xenobiotica ◽  
2009 ◽  
Vol 00 (00) ◽  
pp. 090901052457079-8
Author(s):  
Y. Nishiya ◽  
K. Hagihara ◽  
A. Kurihara ◽  
N. Okudaira ◽  
N.A. Farid ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Human Cytochrome ◽  
Cytochrome P450 2C19
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