Matrix Damage and Chondrocyte Viability Following a Single Impact Load on Articular-Cartilage

1995 ◽  
Vol 322 (1) ◽  
pp. 87-96 ◽  
Author(s):  
J.E. Jeffrey ◽  
D.W. Gregory ◽  
R.M. Aspden
Keyword(s):  
Articular Cartilage ◽  
Impact Load ◽  
Chondrocyte Viability ◽  
Single Impact ◽  
Matrix Damage

scholarly journals The effect of recombinant human fibroblast growth factor-18 on articular cartilage following single impact load

2014 ◽  
Vol 32 (7) ◽  
pp. 923-927 ◽  
Author(s):  
Lynne Barr ◽  
Alan Getgood ◽  
Hans Guehring ◽  
Neil Rushton ◽  
Frances M. D. Henson
Keyword(s):  
Articular Cartilage ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Human Fibroblast ◽  
Impact Load ◽  
Fibroblast Growth ◽  
Single Impact

Ameliorating Glycosaminoglycan (GAG) Loss and Cell Death in Articular Cartilage Following Single-Impact Loading

2007 ◽  
Author(s):  
Roman M. Natoli ◽  
Kyriacos A. Athanasiou
Keyword(s):  
Extracellular Matrix ◽  
Cell Death ◽  
Articular Cartilage ◽  
Impact Loading ◽  
Biomechanical Properties ◽  
Cartilage Explants ◽  
Single Impact ◽  
Igf I ◽  
Post Traumatic ◽  
Bioactive Agents

Impact loading of articular cartilage leads to post-traumatic osteoarthritis (OA) through its effects on the cells and extracellular matrix (ECM) of the tissue. Studies have shown the level of impact or injurious compression correlates with increased cell death, degradation of the ECM, and detrimental changes in biomechanical properties [1]. Recently, several bioactive agents, such as P188 and IGF-I, have shown promising results by reducing cell death following injurious compression of cartilage explants [2, 3].

scholarly journals Doxycycline preserves chondrocyte viability and function in human and calf articular cartilage ex vivo

2020 ◽  
Vol 8 (17) ◽  
pp. e14571
Author(s):  
Li Yue ◽  
Brian Vuong ◽  
Hongwei Yao ◽  
Brett D. Owens
Keyword(s):  
Articular Cartilage ◽  
Ex Vivo ◽  
Chondrocyte Viability ◽  
And Function

DYNAMIC STIFFNESS OF ARTICULAR CARTILAGE BY SINGLE IMPACT MICRO-INDENTATION (SIMI)

2008 ◽  
Vol 41 ◽  
pp. S172 ◽  
Author(s):  
Dieter Wirz ◽  
Corinne Kohler ◽  
Katharina Keller ◽  
Beat Göpfert ◽  
Damir Hudetz ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Dynamic Stiffness ◽  
Single Impact ◽  
Micro Indentation
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