Inside‐out: Chinese academic assessments of large‐scale water infrastructure

Author(s):  
Michael Webber ◽  
Xiao Han ◽  
Sarah Rogers ◽  
Mark Wang ◽  
Hong Jiang ◽  
...  
2020 ◽  
Vol 184 ◽  
pp. 116063 ◽  
Author(s):  
Sjon van Dijk ◽  
Amanda W. Lounsbury ◽  
Arjen Y. Hoekstra ◽  
Ranran Wang

Author(s):  
Robert Elgie ◽  
Emiliano Grossman ◽  
Amy G. Mazur

The larger comparative theory-building and stocktaking goals and questions, and the plan of the book, are presented in this chapter. The major dynamics and developments of French political life are discussed in terms of explaining and understanding the evolution of French politics. The next section provides an overview of French political science to situate the analysis of the study of French politics both inside and outside France in the chapters that follow. The outside-in/inside-out approach of the book is next highlighted in terms of how the vast majority of the chapters follow a common three-part comparative framework: the development of the study of French politics first outside and then inside France and then the emerging research agenda. The chapter then outlines the book’s structure in three sections: conceptual foundations, large-scale processes, and comparative politics dimensions—institutions; parties, elections, and voters; civil society; and policy and policymaking, both domestic and international.


2012 ◽  
Vol 39 (3-4) ◽  
pp. 1039-1075 ◽  
Author(s):  
Rebecca Smalley ◽  
Esteve Corbera

2001 ◽  
Vol 45 (4) ◽  
pp. 64-93 ◽  
Author(s):  
Wendy S. Walters

In Detroit, an artist reclaims recent history and offers it as an everchanging, large-scale environmental performance where discarded objects—carefully presented—embody memory, anger, and hope.


Horizons ◽  
2019 ◽  
Vol 46 (1) ◽  
pp. 121-127
Author(s):  
Brian D. Robinette

Shortly after receiving tenure in 2009, I hit a brick wall. Having poured so much energy into the tenure process, which included a large-scale book project, I found myself intellectually and emotionally spent. Uninspired and unable to gain traction with another major research project during my post-tenure sabbatical, I felt I was wandering through a desert. I had heard rumors about the “post-tenure blues,” but I somehow imagined myself immune.


2018 ◽  
Vol 115 (39) ◽  
pp. E9105-E9114 ◽  
Author(s):  
Aye Myat Myat Thinn ◽  
Zhengli Wang ◽  
Dongwen Zhou ◽  
Yan Zhao ◽  
Brian R. Curtis ◽  
...  

Integrin α/β heterodimer adopts a compact bent conformation in the resting state, and upon activation undergoes a large-scale conformational rearrangement. During the inside-out activation, signals impinging on the cytoplasmic tail of β subunit induce the α/β separation at the transmembrane and cytoplasmic domains, leading to the extended conformation of the ectodomain with the separated leg and the opening headpiece that is required for the high-affinity ligand binding. It remains enigmatic which integrin subunit drives the bent-to-extended conformational rearrangement in the inside-out activation. The β3 integrins, including αIIbβ3 and αVβ3, are the prototypes for understanding integrin structural regulation. The Leu33Pro polymorphism located at the β3 PSI domain defines the human platelet-specific alloantigen (HPA) 1a/b, which provokes the alloimmune response leading to clinically important bleeding disorders. Some, but not all, anti–HPA-1a alloantibodies can distinguish the αIIbβ3 from αVβ3 and affect their functions with unknown mechanisms. Here we designed a single-chain β3 subunit that mimics a separation of α/β heterodimer on inside-out activation. Our crystallographic and functional studies show that the single-chain β3 integrin folds into a bent conformation in solution but spontaneously extends on the cell surface. This demonstrates that the β3 subunit autonomously drives the membrane-dependent conformational rearrangement during integrin activation. Using the single-chain β3 integrin, we identified the conformation-dependent property of anti–HPA-1a alloantibodies, which enables them to differently recognize the β3 in the bent state vs. the extended state and in the complex with αIIb vs. αV. This study provides deeper understandings of integrin conformational activation on the cell surface.


2020 ◽  
Vol 492 (3) ◽  
pp. 3128-3142 ◽  
Author(s):  
J Grady ◽  
V Belokurov ◽  
N W Evans

ABSTRACT We exploit the extensive Gaia Data Release 2 set of long-period variables to select a sample of O-rich Miras throughout the Milky Way disc and bulge for study. Exploiting the relation between Mira pulsation period and stellar age/chemistry, we slice the stellar density of the Galactic disc and bulge as a function of period. We find that the morphology of both components evolves as a function of stellar age/chemistry with the stellar disc being stubby at old ages, becoming progressively thinner and more radially extended at younger stellar ages, consistent with the picture of inside-out and upside-down formation of the Milky Way’s disc. We see evidence of a perturbed disc, with large-scale stellar overdensities visible both in and away from the stellar plane. We find that the bulge is well modelled by a triaxial boxy distribution with an axial ratio of ∼1:0.4:0.3. The oldest of the Miras (∼9–10 Gyr) show little bar-like morphology, while the younger stars appear inclined at a viewing angle of ∼21° to the Sun–Galactic Centre line. This suggests that bar formation and buckling took place 8–9 Gyr ago, with the older Miras being hot enough to avoid being trapped by the growing bar. We find the youngest Miras to exhibit a strong peanut morphology, bearing the characteristic X-shape of an inclined bar structure.


1999 ◽  
Vol 173 ◽  
pp. 243-248
Author(s):  
D. Kubáček ◽  
A. Galád ◽  
A. Pravda

AbstractUnusual short-period comet 29P/Schwassmann-Wachmann 1 inspired many observers to explain its unpredictable outbursts. In this paper large scale structures and features from the inner part of the coma in time periods around outbursts are studied. CCD images were taken at Whipple Observatory, Mt. Hopkins, in 1989 and at Astronomical Observatory, Modra, from 1995 to 1998. Photographic plates of the comet were taken at Harvard College Observatory, Oak Ridge, from 1974 to 1982. The latter were digitized at first to apply the same techniques of image processing for optimizing the visibility of features in the coma during outbursts. Outbursts and coma structures show various shapes.


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