Effective strategy for the production of novel magnetite poly(vinyl chloride) nanocomposite films with iron oxide nanoparticles double-capped through citric acid and vitamin C

2015 ◽  
Vol 23 ◽  
pp. E4-E14 ◽  
Author(s):  
Shadpour Mallakpour ◽  
Mashal Javadpour
2020 ◽  
Vol 46 (8) ◽  
pp. 10942-10951 ◽  
Author(s):  
Sidra Khan ◽  
Zaheer H. Shah ◽  
Saira Riaz ◽  
Naveed Ahmad ◽  
Shumaila Islam ◽  
...  

2013 ◽  
Vol 110 ◽  
pp. 329-334 ◽  
Author(s):  
L. Li ◽  
K.Y. Mak ◽  
C.W. Leung ◽  
K.Y. Chan ◽  
W.K. Chan ◽  
...  

2021 ◽  
Vol 12 (3) ◽  
pp. 3215-3224

The present study aimed to explore the synergistic anticancer effect of combined L-ascorbic acid (LAA) with superparamagnetic iron oxide nanoparticles (SPIONs) on adenocarcinoma gastric cell line (AGS). Fe3O4-LAA was synthesized using the reverse co-precipitation technique. XRD, FT-IR, FESEM, and TEM were employed to characterize the synthesized nanoparticles. MTT test and Real-time PCR were performed to investigate the cytotoxicity and apoptosis induced by treatments. The present study indicated that the anticancer properties of vitamin C were increased when employed as the Fe3O4-LAA nanoparticles. A dose-dependent manner on the effect of Fe3O4-LAA on investigated genes was observed; p53 gene expression changes in high and low doses of Fe3O4-LAA were 7.4 and 3.1 fold, respectively; accordingly, Bcl2 gene expression under treatment with high and low doses of Fe3O4-LAA was reduced by 71% and 25%, respectively. In conclusion, our results indicated that Fe3O4-LAA nanoparticles might be an efficient agent for cancer treatment.


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