Biocompatible citric acid-coated iron oxide nanoparticles to enhance the activity of first-line anti-TB drugs inMycobacterium smegmatis

2015 ◽  
Vol 90 (10) ◽  
pp. 1773-1781 ◽  
Author(s):  
Priyanka Padwal ◽  
Rajdip Bandyopadhyaya ◽  
Sarika Mehra
Keyword(s):  
Iron Oxide ◽  
Citric Acid ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
First Line

Antimicrobial activity of citric acid functionalized iron oxide nanoparticles –Superparamagnetic effect

2020 ◽  
Vol 46 (8) ◽  
pp. 10942-10951 ◽  
Author(s):  
Sidra Khan ◽  
Zaheer H. Shah ◽  
Saira Riaz ◽  
Naveed Ahmad ◽  
Shumaila Islam ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Iron Oxide ◽  
Citric Acid ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles

Effect of synthesis conditions on the properties of citric-acid coated iron oxide nanoparticles

2013 ◽  
Vol 110 ◽  
pp. 329-334 ◽  
Author(s):  
L. Li ◽  
K.Y. Mak ◽  
C.W. Leung ◽  
K.Y. Chan ◽  
W.K. Chan ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Citric Acid ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Synthesis Conditions

scholarly journals Biocompatible Magnetic Colloidal Suspension Used as a Tool for Localized Hyperthermia in Human Breast Adenocarcinoma Cells: Physicochemical Analysis and Complex In Vitro Biological Profile

Nanomaterials ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1189
Author(s):  
Elena-Alina Moacă ◽  
Claudia-Geanina Watz ◽  
Vlad Socoliuc ◽  
Roxana Racoviceanu ◽  
Cornelia Păcurariu ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Citric Acid ◽  
Iron Oxide Nanoparticles ◽  
Colloidal Suspension ◽  
Physicochemical Analysis ◽  
Breast Adenocarcinoma ◽  
Oxide Nanoparticles ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Magnetic Iron Oxide ◽  
Adenocarcinoma Cells

Magnetic iron oxide nanoparticles are the most desired nanomaterials for biomedical applications due to their unique physiochemical properties. A facile single-step process for the preparation of a highly stable and biocompatible magnetic colloidal suspension based on citric-acid-coated magnetic iron oxide nanoparticles used as an effective heating source for the hyperthermia treatment of cancer cells is presented. The physicochemical analysis revealed that the magnetic colloidal suspension had a z-average diameter of 72.7 nm at 25 °C with a polydispersity index of 0.179 and a zeta potential of −45.0 mV, superparamagnetic features, and a heating capacity that was quantified by an intrinsic loss power analysis. Raman spectroscopy showed the presence of magnetite and confirmed the presence of citric acid on the surfaces of the magnetic iron oxide nanoparticles. The biological results showed that breast adenocarcinoma cells (MDA-MB-231) were significantly affected after exposure to the magnetic colloidal suspension with a concentration of 30 µg/mL 24 h post-treatment under hyperthermic conditions, while the nontumorigenic (MCF-10A) cells exhibited a viability above 90% under the same thermal setup. Thus, the biological data obtained in the present study clearly endorse the need for further investigations to establish the clinical biological potential of synthesized magnetic colloidal suspension for magnetically triggered hyperthermia.

Effect of citric acid on the morpho-structural and magnetic properties of ultrasmall iron oxide nanoparticles

2021 ◽  
pp. 160779
Author(s):  
Alexander Omelyanchik ◽  
Franciscarlos Gomes da Silva ◽  
Guilherme Gomide ◽  
Ivan Kozenkov ◽  
Jerome Depeyrot ◽  
...  
Keyword(s):  
Magnetic Properties ◽  
Iron Oxide ◽  
Citric Acid ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Structural And Magnetic Properties

Iron Oxide Nanoparticles Synthesized via Green Tea Extract for Doxorubicin Delivery

2020 ◽  
Vol 16 ◽  
Author(s):  
Lei Nie ◽  
Chenlei Cai ◽  
Meng Sun ◽  
Fang Zhang ◽  
Lingyun Zheng ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Citric Acid ◽  
Iron Oxide Nanoparticles ◽  
Green Tea ◽  
Drug Carrier ◽  
Green Tea Extract ◽  
Cancer Drug ◽  
Control Group ◽  
Oxide Nanoparticles ◽  
Tea Extract

Background:: Due to the limitation of conventional cancer treatment using chemotherapy, the nanoparticle therapeutics showed enhanced efficacy with alleviating side effects. Objective:: The superparamagnetic iron oxide nanoparticles (T-C-SPION) would be prepared for doxorubicin (DOX) loading and delivery. Methods:: Here, we reported a simple green strategy to fabricate T-C-SPION using green tea extract and citric acid. Also, the anti-cancer drug, DOX, was used as a model drug to fabricate DOX-loaded nanoparticles. Results:: The formed T-C-SPION nanoparticles were spherical with a diameter of 23.8 ± 0.8 nm, confirmed by Transmission Electron Microscopy (TEM). Besides, Dynamic Light Scattering (DLS) revealed that the prepared nanoparticles were water-dispersible and stable while stored in water for 6 weeks. The CCK-8 assay showed that T-C-SPION had a good cytocompatibility using different iron concentrations (10 ~ 120 ug/mL). Furthermore, T-C-SPION had a higher DOX encapsulation efficiency (Eencaps), around 43.2 ± 1.8 %, which resulted in a lagged release profile of DOX, compared to other types of iron oxide nanoparticles using green tea or citric acid alone. Next, cell viability assay indicated that T-C-SPION with a higher Eencaps showed superior and sustained cytotoxicity compared to the control group. Conclusion:: The developed iron oxide nanoparticles synthesized by green tea extract and citric acid in this paper could be considered as a potential drug carrier for cancer therapy applications.

Synthesis of high intrinsic loss power aqueous ferrofluids of iron oxide nanoparticles by citric acid-assisted hydrothermal-reduction route

2012 ◽  
Vol 187 ◽  
pp. 20-26 ◽  
Author(s):  
Behshid Behdadfar ◽  
Ahmad Kermanpur ◽  
Hojjat Sadeghi-Aliabadi ◽  
Maria del Puerto Morales ◽  
Morteza Mozaffari
Keyword(s):  
Iron Oxide ◽  
Citric Acid ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Intrinsic Loss ◽  
Hydrothermal Reduction
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