scholarly journals OC01.03: How does the IVF treatment protocol affect subendometrial blood flow prior to ovulation?

2011 ◽  
Vol 38 (S1) ◽  
pp. 2-2
Author(s):  
S. Sur ◽  
A. Elfituri ◽  
J. Clewes ◽  
B. Campbell ◽  
N. Raine-Fenning
Keyword(s):  
Blood Flow ◽  
Treatment Protocol ◽  
Subendometrial Blood Flow

The role of antioxidants in the complex therapy of patients with endometriosis-associated infertility

2020 ◽  
Vol 19 (6) ◽  
pp. 28-33
Author(s):  
M.G. Khatlamadzhiyan ◽  
◽  
E.V. Kharitonova ◽  
L.N. Shcherbakova ◽  
E.I. Kalenikova ◽  
...  
Keyword(s):  
Blood Flow ◽  
Reproductive Function ◽  
Control Group ◽  
Complex Therapy ◽  
Endometrium Receptivity ◽  
Infertile Patients ◽  
Subendometrial Blood Flow ◽  
Endometrial Blood Flow ◽  
Fertile Women

Objective. To study the role of antioxidants in the complex therapy of patients with endometriosis-associated infertility on the example of evaluating the effectiveness of ubidecarenone. Patients and methods. Forty-three patients with endometriosis-associated infertility and nineteen fertile women with complete reproductive function were examined. In order to improve the receptivity of endometrium and correct the antioxidant status in infertile patients with endometriosis after laparoscopy, therapy with Synergin® was administered at a dosage of 2 capsules per day for 3 months. After therapy, an assessment of endometrium and intrauterine perfusion was made. Results. There was a significant decrease in intrauterine perfusion in patients with endometriosis-associated infertility compared to the control group. However, after therapy with Synergin® within 3 months and correction of endothelial dysfunction in infertile patients with endometriosis, an improvement in intrauterine perfusion was revealed. Thus, prior to therapy, subendometrial blood flow was assessed in 13% of patients as satisfactory, in 77% – it was reduced, in 10% – it was absent; after therapy, 86% of patients showed satisfactory blood flow and 14% had decreased blood flow. Endometrial blood flow was reduced in 32% of patients and in 68% were absent prior to treatment, and after treatment, it was assessed as satisfactory in 45% and was reduced in 55%. Conclusion. Pathogenetic antioxidant therapy is necessary in the complex therapy of infertility in patients with external genital endometriosis after surgical treatment. Key words: α-Tocopherol, infertility, coenzyme Q10, endometrium receptivity, endometriosis

Assessment of endometrial and subendometrial blood flow in women undergoing frozen embryo transfer cycles

2014 ◽  
Vol 28 (3) ◽  
pp. 343-351 ◽  
Author(s):  
Anupa Nandi ◽  
Wellington P. Martins ◽  
Kannamannadiar Jayaprakasan ◽  
Jeanette S. Clewes ◽  
Bruce K. Campbell ◽  
...  
Keyword(s):  
Blood Flow ◽  
Embryo Transfer ◽  
Frozen Embryo Transfer ◽  
Subendometrial Blood Flow

Effects of Cobalamin (Vitamin B12) on Gentamicin Induced Nephrotoxicity in Rat

Drug Research ◽  
2017 ◽  
Vol 67 (12) ◽  
pp. 710-718 ◽  
Author(s):  
Saeed Hajihashemi ◽  
Zeinab Hamidizad ◽  
Ali Rahbari ◽  
Fatemeh Ghanbari ◽  
Zohre Motealeghi
Keyword(s):  
Blood Flow ◽  
Defense Mechanisms ◽  
Antioxidant Defense ◽  
Kidney Tissue ◽  
Treatment Protocol ◽  
Renal Tissue ◽  
Serum Electrolytes ◽  
Main Factors ◽  
Nephroprotective Effect ◽  
Sodium And Potassium

Abstract Background The main side effect of gentamicin is nephrotoxicity. The effect of cobalamin (Cob) was investigated on gentamicin nephrotoxicity in rats. Methods Renal injury induced by i.p. injection of gentamicin (100 mg/kg) for 8 consecutive days. Cobalamin (6 mg/kg/day, i.p) treatment was done for 8 consecutive days as co-treatment and post-treatment protocol. Results Cobalamin significantly increased creatinine clearance levels and renal blood flow which were reduced by gentamicin. Also, cobalamin significantly improved serum electrolytes (sodium and potassium) levels which were disturbed by gentamicin. Cobalamin significantly compensated deficits in the antioxidant defense mechanisms, suppressed lipid per oxidation and ameliorated renal tissue damage mediated by gentamicin. Conclusion The results of the current study indicated that cobalamin effectively protected the kidney tissue against gentamicin induced acute nephrotoxicity in rats. The antioxidant and anti-inflammatory activities can be supposed the main factors responsible for the nephroprotective effect of cobalamin.

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