P26.10: The role of 2D and 3D transvaginal sonography on the diagnosis of enterovaginal fistula

2010 ◽  
Vol 36 (S1) ◽  
pp. 272-272
Author(s):  
D. C. Prete ◽  
A. C. Morandini ◽  
T. Ito ◽  
F. M. Sobrinho ◽  
J. L. Souza ◽  
...  
Author(s):  
Pooja J. Mise ◽  
Sangamesh J. Mise ◽  
Aditya Mise ◽  
Margol Siddappa

Background: Transvaginal sonography (TVS) is a new diagnostic technique used for the evaluation of the female pelvis. The objective of the present study was to study the role of TVS and to assess the diagnostic accuracy in gynecological disorders.Methods: Total number of 100 patients attending OPDs with various complaints was selected by random technique of the study.  All the patients have informed consent and thorough clinical examination including general, systemic and pelvic examination was conducted after taking a detailed history then the patients underwent TVS followed by one of the procedures like fractional curettage, dilatation and curettage and abdominal hysterectomy (with or without conservation of ovaries) or conservative management with regular follow up.Results: The sensitivity of TVS in diagnosing dysfunctional uterine bleeding (DUB) and pelvic inflammatory diseases (PID) was 100% and specificity was 85.1% and 95% respectively. For fibroids and ovarian mass diagnosis, sensitivity was 68.9% and 80.9% respectively and specificity was 100%. Diagnostic accuracy of clinical diagnosis was 70.0% whereas TVS had 94.0% of diagnostic accuracy in diagnosing various gynecological disorders.Conclusions: The final outcome is that TVS examination is an important non-invasive investigation, can be used as important diagnostic method in various gynecological disorders as it has got a high diagnostic accuracy.


10.28945/3018 ◽  
2006 ◽  
Author(s):  
Anton Nijholt

There are many ways to present information to visitors and users of 2D and 3D interface environments. In these virtual environments we can provide visitors with simulations of real environments, including simulations of presenters in such environments (a lecturer, a sales agent, a receptionist, a museum guide) and including audience participation in these environments. Our research aims at generating presentations from available multimedia information. In particular, we would like to see the generation of presentations by embodied conversational agents that employ verbal and nonverbal capabilities. In the past we have seen the introduction of embodied agents and robots that take the role of a museum guide, a news presenter, a teacher, a receptionist, or someone who is trying to sell insurance, houses or tickets. In all these cases the embodied agent needs to explain and to describe. The automatic generation of presentations and presentation agents from information sources is still too ambitious a task. Therefore we look at research from the perspective of the design of tools that can support presenters or can help to provide natural access to presentations and lectures. Can we use a given collection of sheets and maybe other accessible media sources to design, create and generate an embodied presenter? Among others we discuss manual annotation of available information and the way in which presenter agents can use it. Clearly, the development of tools for these purposes is a first step towards automating the generation of presentations and presentation agents.


2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Sarika Singh ◽  
Eric Prestat ◽  
Liang-Feng Huang ◽  
James M. Rondinelli ◽  
Sarah J. Haigh ◽  
...  
Keyword(s):  

2019 ◽  
Vol 20 (23) ◽  
pp. 6017 ◽  
Author(s):  
Prospero Civita ◽  
Diana M. Leite ◽  
Geoffrey Pilkington

The role of astrocytes in the glioblastoma (GBM) microenvironment is poorly understood; particularly with regard to cell invasion and drug resistance. To assess this role of astrocytes in GBMs we established an all human 2D co-culture model and a 3D hyaluronic acid-gelatin based hydrogel model (HyStem™-HP) with different ratios of GBM cells to astrocytes. A contact co-culture of fluorescently labelled GBM cells and astrocytes showed that the latter promotes tumour growth and migration of GBM cells. Notably, the presence of non-neoplastic astrocytes in direct contact, even in low amounts in co-culture, elicited drug resistance in GBM. Recent studies showed that non-neoplastic cells can transfer mitochondria along tunneling nanotubes (TNT) and rescue damaged target cancer cells. In these studies, we explored TNT formation and mitochondrial transfer using 2D and 3D in vitro co-culture models of GBM and astrocytes. TNT formation occurs in glial fibrillary acidic protein (GFAP) positive “reactive” astrocytes after 48 h co-culture and the increase of TNT formations was greater in 3D hyaluronic acid-gelatin based hydrogel models. This study shows that human astrocytes in the tumour microenvironment, both in 2D and 3D in vitro co-culture models, could form TNT connections with GBM cells. We postulate that the association on TNT delivery non-neoplastic mitochondria via a TNT connection may be related to GBM drug response as well as proliferation and migration.


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