OP27.01: Prediction of neonatal outcome in 20 fetuses with severe left congenital diaphragmatic hernia submitted to percutaneous fetal tracheal occlusion by the observed/expected fetal lung volumes

2010 ◽  
Vol 36 (S1) ◽  
pp. 130-131
Author(s):  
R. Ruano ◽  
E. Takashi ◽  
S. Duarte ◽  
M. M. Silva ◽  
U. Tannuri ◽  
...  
2000 ◽  
Vol 183 (5) ◽  
pp. 1067-1069 ◽  
Author(s):  
Danielle S. Walsh ◽  
Anne M. Hubbard ◽  
Oluyinka O. Olutoye ◽  
Lori J. Howell ◽  
Timothy M. Crombleholme ◽  
...  

Author(s):  
Joseph Davidson ◽  
Alena Uus ◽  
Alexia Egloff Collado ◽  
Milou Van Poppel ◽  
Jacqueline Matthew ◽  
...  

Abstract Objective:Evaluate deformable slice-to-volume registration (DSVR) to calculate 3D-segmented total lung volume (TLV) in fetuses with congenital diaphragmatic hernia, congenital lung lesions and healthy controls, with comparison to 2D-manual segmentation. Design:Pilot study Setting:Regional fetal medicine referral centre Sample:Fetal MRIs performed for clinical indications (abnormal cases) or as research participants (healthy controls) Methods:Sixteen MRI datasets of fetuses (22-32 weeks GA). Diagnosis: CDH(n=5), CPAM(n=2), CDH with BPS(n=1) and healthy control(n=8). DSVR was used for reconstruction of 3D isotropic (0.85 mm) volumes of fetal body followed by semi-automated lung segmentation. The resulting 3D TLV were compared to the traditional 2D-based volumetry, and a normogram of DSVR-derived fetal lung volumes from 100 cases was produced. Main Outcome Measures:Concordance with 2D-volumetry assessed with Bland-Altman analysis, results of segmentations presented visually. Observed/Expected values were calculated for abnormal cases based upon the normogram. Results:DSVR-derived TLV values have high correlation with the 2D-based measurements but with a consistently lower volume; bias -1.44cm3 [95% limits: -2.6 to -0.3] with improved resolution able to exclude hilar structures even in severe motion corruption or in cases of lung hypoplasia. Conclusions:Application of DSVR for fetal MRI provides a solution for analysis of motion corrupted scans and does not suffer from the interpolation error inherent in 2D-segmentation as per current clinical practice. It increases information content of acquired data in terms of visualising organs in 3D space and quantification of volumes, which we believe will have important value for counselling and surgical planning. Keywords:Fetal MRI; congenital diaphragmatic hernia; CPAM; lung volume


2016 ◽  
Vol 35 (6) ◽  
pp. 1159-1166 ◽  
Author(s):  
Rodrigo Ruano ◽  
Ingrid Schwach Werneck Britto ◽  
Nicolas Sananes ◽  
Wesley Lee ◽  
Haleh Sangi-Haghpeykar ◽  
...  

2015 ◽  
Vol 29 (18) ◽  
pp. 3030-3034 ◽  
Author(s):  
Nicolas Sananes ◽  
Carlota Rodo ◽  
Jose Luis Peiro ◽  
Ingrid Schwach Werneck Britto ◽  
Haleh Sangi-Haghpeykar ◽  
...  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jiyoon Jeong ◽  
Byong Sop Lee ◽  
Teahyen Cha ◽  
Euiseok Jung ◽  
Ellen Ai-Rhan Kim ◽  
...  

Abstract Background Right-sided congenital diaphragmatic hernia (RCDH) is relatively rare compared with left-sided congenital diaphragmatic hernia (LCDH). Clinical data of RCDH, especially with respect to antenatal prediction of neonatal outcome, are lacking. The aim of this study was to report the treatment outcomes of patients with antenatally diagnosed RCDH and to evaluate the predictability of observed-to-expected lung area-to-head circumference ratio (O/E LHR) for perinatal outcomes, focused on mortality or extracorporeal membrane oxygenation (ECMO) requirement. Methods We retrospectively reviewed the medical records of newborn infants with isolated RCDH. We analyzed and compared the clinical and prenatal characteristics including the fetal lung volume, which was measured as the O/E LHR, between the survivors and the non-survivors. Results A total of 26 (66.7%) of 39 patients with isolated RCDH survived to discharge. The O/E LHR was significantly greater in survivors (64.7 ± 21.2) than in non-survivors (40.5 ± 23.4) (P =.027). It was greater in survivors without ECMO requirement (68.3 ± 15.1) than non-survivors or those with ECMO requirement (46.3 ± 19.4; P = .010). The best O/E LHR cut-off value for predicting mortality in isolated RCDH was 50. Conclusions The findings in this study suggest that O/E LHR, a well-characterized prognostic indicator in LCDH, could be applied to a fetus with antenatally diagnosed RCDH. A large cohort study is required to verify the association between O/E LHR values and the graded severity of RCDH.


2014 ◽  
Vol 49 (5) ◽  
pp. 688-693 ◽  
Author(s):  
Irving J. Zamora ◽  
Oluyinka O. Olutoye ◽  
Darrell L. Cass ◽  
Sara C. Fallon ◽  
David A. Lazar ◽  
...  

2010 ◽  
Vol 31 (4) ◽  
pp. 269-273 ◽  
Author(s):  
K Terui ◽  
A Omoto ◽  
H Osada ◽  
T Hishiki ◽  
T Saito ◽  
...  

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