scholarly journals VP20.11: An intriguing case of fetal umbilical‐portal‐systemic venous shunt

2021 ◽  
Vol 58 (S1) ◽  
pp. 182-182
Author(s):  
S. Tartaglia ◽  
A. Romiti ◽  
S. Abu Samra ◽  
M. Salvatori ◽  
G. Rizzo
Keyword(s):  
Venous Shunt

ADP Plays a Key Role in Thrombogenesis in Rats

1988 ◽  
Vol 59 (02) ◽  
pp. 225-230 ◽  
Author(s):  
J P Maffrand ◽  
A Bernat ◽  
D Delebassée ◽  
G Defreyn ◽  
J P Cazenave ◽  
...  
Keyword(s):  
Platelet Aggregation ◽  
Bleeding Time ◽  
Thrombus Formation ◽  
Vascular Wall ◽  
Cyclooxygenase Inhibitors ◽  
High Dose ◽  
Silk Thread ◽  
Dense Granules ◽  
Prolonged Bleeding Time ◽  
Venous Shunt

SummaryThe relative importance of ADP, arachidonic acid metabolites and serotonin as thrombogenic factors was evaluated in rats by comparing, after oral administration, the effects of two inhibitors of ADP-induced platelet aggregation (ticlopidine and PCR 4099), three cyclo-oxygenase inhibitors (aspirin, triflusal and indobufen) and a selective serotonin 5HT2 receptor antagonist (ketanserin) on platelet aggregation, in four platelet-dependent thrombosis models and on bleeding time. Platelet aggregation induced by ADP and collagen was completely inhibited by ticlopidine and PCR 4099 whereas only the collagen aggregation was reduced by the cyclo-oxygenase inhibitors. Ketanserin or a depletion of platelet serotonin by reserpine did not affect platelet aggregation. Ticlopidine and PCR 4099 greatly prolonged rat tail transection bleeding time. This is probably related to their known ability to inhibit ADP-mediated platelet aggregation. In contrast, the cyclooxygenase inhibitors did not affect bleeding time at all. Reserpine and ketanserin prolonged bleeding time by interfering with the action of serotonin on the vascular wall. Ticlopidine and PCR4099 were very potent antithrombotics in all the models. Aspirin, only at a high dose, inhibited poorly thrombus formation on a silk thread in an arterio-venous shunt, suggesting that the inhibition of cyclo-oxygenase was not responsible. Triflusal was inactive in all models while indobufen slightly reduced thrombus formation in the silk thread and metallic coil models. Ketanserin and reserpine reduced thrombus only in the metallic coil model. Thrombus formation was greatly reduced in fawn-hooded rats, which lack ADP in their platelet dense granules because of a genetic storage pool deficiency. Taken together, the results obtained with the drugs and with the fawn-hooded rats support the concept that ADP plays a key role in thrombogenesis in rats.

Thoracic Lymph Duct Catheterization with a Venous Shunt in the Nonhuman Primate

2021 ◽  
pp. 1-9
Author(s):  
Jon Ehrmann ◽  
Claudia Generaux ◽  
Sharon Ostergaard ◽  
Wendy Johnson ◽  
Anne Rose ◽  
...  
Keyword(s):  
Nonhuman Primate ◽  
Venous Shunt ◽  
Lymph Duct

scholarly journals Portal Systemic Venous Shunt

1965 ◽  
Vol 49 (6) ◽  
pp. 656-661 ◽  
Author(s):  
Edward A. Gall ◽  
Alfred M. Keirle
Keyword(s):  
Venous Shunt

Hypergalactosaemia in a newborn: self-limiting intrahepatic portosystemic venous shunt

1997 ◽  
Vol 156 (9) ◽  
pp. 719-722 ◽  
Author(s):  
R. Gitzelmann ◽  
I. Forster ◽  
U. V. Willi
Keyword(s):  
Venous Shunt

scholarly journals A modified technique for the production of an arterio-venous shunt in sheep, allowing a comparison of biocompatibility of synthetic materials

1990 ◽  
Vol 24 (1) ◽  
pp. 44-47 ◽  
Author(s):  
W. A. Stertmann ◽  
H. H. Scheld ◽  
J. Kubicek ◽  
H. Fitz ◽  
H. Lukas ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Drug Safety ◽  
Extracorporeal Circulation ◽  
Jugular Vein ◽  
Artificial Kidney ◽  
Modified Technique ◽  
Multiple Administration ◽  
Synthetic Materials ◽  
Venous Shunt ◽  
Clinical Impairment

Polytetrafluorethylene (PTFE) prostheses were implanted in 12 sheep as a shunt between the carotid artery and the jugular vein using an end-to-side anastomosis technique. This technique allows repeated tests of the pharmacological and toxicological safety of artificial kidney units after both single and multiple administration. Further-more, it enables the investigation of detoxification of compounds via dialysis, thus contributing to drug safety. Implantation of the prosthesis was uncomplicated. Connection to the extracorporeal circulation was achieved via catheters and maintained using a pump with an output of up to 300 ml/min. This enabled maintenance of extracorporeal circulation for several hours without clinical impairment to the animals. The AV-shunts remained functional for between 8 and 253 days (mean 112·3 days).

SUBUNGUAL GLOMUS TUMOUR: THE ENIGMATIC CAUSE OF CHRONIC PAINFUL FINGER PULP - A CASE REPORT

2021 ◽  
pp. 11-12
Author(s):  
Mohit Naren Kondapalli ◽  
Kishore Babu EP ◽  
Affee Asma
Keyword(s):  
Soft Tissue ◽  
Subcutaneous Tissue ◽  
Soft Tissue Tumors ◽  
Glomus Tumour ◽  
Connective Tissue Capsule ◽  
Venous Shunt ◽  
Fourth Decade ◽  
Tissue Capsule ◽  
Dermis Layer ◽  
Glomus Body

Glomus tumour, also referred to as Barré–Masson syndrome is an enigmatic, rare, painful tumour that is that represents a proliferation of the normal capsular-neural glomus apparatus. These are rare hamartomas that arise from the traditional glomus apparatus, located in subcutaneous tissue These are benign soft tissue neoplasms presenting usually within the second to fourth decade of life, originating from the glomus body. It accounts for 1-5% of all upper limb soft tissue tumors . It's a component of the dermis layer of the [1] skin, involved in thermoregulation. It structurally consists of an arterio-venous shunt which is surrounded by a connective tissue capsule and is found in increased amounts in the ngers and toes.

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