scholarly journals VP42.12: Elevated pulsatility index of ductus venosus Doppler flow reflects ventricular wall stress in recipient twins with Twin–twin transfusion syndrome

2020 ◽  
Vol 56 (S1) ◽  
pp. 243-243
Author(s):  
M. Takano ◽  
M. Nakata ◽  
J. Sakuma ◽  
S. Nagasaki ◽  
M. Morita
Keyword(s):  
Pulsatility Index ◽  
Wall Stress ◽  
Ductus Venosus ◽  
Ventricular Wall ◽  
Doppler Flow

scholarly journals Left Ventricular Wall Stress Calculated from One-Plane Cineangiography

1970 ◽  
Vol 26 (1) ◽  
pp. 71-83 ◽  
Author(s):  
HERMAN L. FALSETTI ◽  
ROBERT E. MATES ◽  
COLIN GRANT ◽  
DAVID G. GREENE ◽  
IVAN L. BUNNELL
Keyword(s):  
Wall Stress ◽  
Left Ventricular ◽  
Left Ventricular Wall ◽  
Ventricular Wall

scholarly journals Mechanically Unloading the Left Ventricle Before Coronary Reperfusion Reduces Left Ventricular Wall Stress and Myocardial Infarct Size

Circulation ◽  
2013 ◽  
Vol 128 (4) ◽  
pp. 328-336 ◽  
Author(s):  
Navin K. Kapur ◽  
Vikram Paruchuri ◽  
Jose Angel Urbano-Morales ◽  
Emily E. Mackey ◽  
Gerard H. Daly ◽  
...  
Keyword(s):  
Left Ventricle ◽  
Infarct Size ◽  
Myocardial Infarct ◽  
Wall Stress ◽  
Left Ventricular ◽  
Left Ventricular Wall ◽  
Myocardial Infarct Size ◽  
Ventricular Wall ◽  
Coronary Reperfusion

Significance of left ventricular wall stress in infants with atrioventricular septal defect, common atrioventricular orifice and regurgitation across the left atrioventricular valve

1991 ◽  
Vol 1 (4) ◽  
pp. 390-395
Author(s):  
Masahi Seguchi ◽  
Makoto Nakazawa ◽  
Kataro Oyama ◽  
Masa-aki Kawada ◽  
Hiromi Kurosawa ◽  
...  
Keyword(s):  
Septal Defect ◽  
Primary Repair ◽  
Wall Stress ◽  
Ventricular Volume ◽  
Atrioventricular Septal Defect ◽  
Left Ventricular ◽  
Ventricular Wall ◽  
Atrioventricular Valve ◽  
Left Heart Failure ◽  
Young Infants

SummaryThe outcome of primary repair in young infants having atrioventricular septal defect with a common atrioventricular orifice and regurgitation across the left atrioventricular valve is not yet satisfactory. We studied the significance of the characteristics of left ventricular volume and mass and the predicted wall stress for the outcome of repair in 13 infants with this lesion. Three patients died of left heart failure after operation, although neither residual shunting at ventricular level nor regurgitation across the left atrioventricular valve was present. End-diastolic volume and ejection fraction of the left ventricle were 228 ±66% and 0.65 ±0.06 of normal, respectively, with no difference between the survivors and non-survivors. End-diastolic thickness of the posterior ventricular wall, determined by echocardiogram, was within normal range for body size in all patients.

Relation of B-type natriuretic peptide to left ventricular wall stress as assessed by cardiac magnetic resonance imaging in patients with dilated cardiomyopathy

2007 ◽  
Vol 85 (8) ◽  
pp. 790-799 ◽  
Author(s):  
P. Alter ◽  
H. Rupp ◽  
M.B. Rominger ◽  
A. Vollrath ◽  
F. Czerny ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Wall Stress ◽  
Left Ventricular ◽  
Ventricular Wall ◽  
Resonance Imaging ◽  
Sphere Model ◽  
Lv Mass ◽  
Systolic Wall Stress

Ventricular loading conditions are crucial determinants of cardiac function and prognosis in heart failure. B-type natriuretic peptide (BNP) is mainly stored in the ventricular myocardium and is released in response to an increased ventricular filling pressure. We examined, therefore, the hypothesis that BNP serum concentrations are related to ventricular wall stress. Cardiac magnetic resonance imaging (MRI) was used to assess left ventricular (LV) mass and cardiac function of 29 patients with dilated cardiomyopathy and 5 controls. Left ventricular wall stress was calculated by using a thick-walled sphere model, and BNP was assessed by immunoassay. LV mass (r = 0.73, p < 0.001) and both LV end-diastolic (r = 0.54, p = 0.001) and end-systolic wall stress (r = 0.66, p < 0.001) were positively correlated with end-diastolic volume. LV end-systolic wall stress was negatively related to LV ejection fraction (EF), whereas end-diastolic wall stress was not related to LVEF. BNP concentration correlated positively with LV end-diastolic wall stress (r = 0.50, p = 0.002). Analysis of variance revealed LV end-diastolic wall stress as the only independent hemodynamic parameter influencing BNP (p < 0.001). The present approach using a thick-walled sphere model permits determination of mechanical wall stress in a clinical routine setting using standard cardiac MRI protocols. A correlation of BNP concentration with calculated LV stress was observed in vivo. Measurement of BNP seems to be sufficient to assess cardiac loading conditions. Other relations of BNP with various hemodynamic parameters (e.g., EF) appear to be secondary. Since an increased wall stress is associated with cardiac dilatation, early diagnosis and treatment could potentially prevent worsening of the outcome.

Abstract 17200: Plasma BNP Declines in the First Two Years After Transplant and is Elevated at the Time of Treated Rejection

Circulation ◽  
2018 ◽  
Vol 138 (Suppl_1) ◽  
Author(s):  
Tom J Valikodath ◽  
Neal Jorgensen ◽  
Erin Albers ◽  
Borah Hong ◽  
Joshua Friedland-Little ◽  
...  
Keyword(s):  
Heart Failure ◽  
Natriuretic Peptide ◽  
Ventricular Dysfunction ◽  
Multivariable Analysis ◽  
Wall Stress ◽  
Ventricular Wall ◽  
The Relationship ◽  
Pediatric Recipients ◽  
Over Time

Introduction: Plasma B-type natriuretic peptide (BNP) is a biomarker used to diagnose and monitor ventricular dysfunction and heart failure. However, the response of the allograft to produce BNP from ventricular wall stress and inflammation may be different, particularly in an understudied population such as pediatric recipients. Hypothesis: BNP levels decrease over time after transplant as the allograft recovers; but BNP will be higher during rejection. Methods: Enrolled all heart recipients from January 2007 to December 2016. Rejection surveillance included serial echocardiography, annual biopsy, and BNP q 1-3 months. Rejection is defined as requiring augmentation of immunosuppression from biopsy grade ≥ 2R or ≥ pAMR2 or from clinical diagnosis. Results: Among 114 patients studied, 60% were male with age at transplant 5.8 ± SD 6.5 yrs. Follow-up was 3.7 ± 2.7 yrs and 37 patients (32%) experienced 75 episodes of rejection. A total of 8358 BNP samples were obtained. BNP decreased linearly after transplant leveling off after 2 years (Fig 1). BNP was 671 ± 1115 (n=75) at rejection vs. 187 ± 423 pg/mL (n=501) without rejection confirmed by biopsy. By multivariable analysis, Ln BNP was associated with rejection (RR 1.56; 95% CI 1.35-1.80). Figure 2 shows the relationship between change in BNP and risk of rejection. Multivariable longitudinal Cox proportional model incorporating BNPs leading to 1 st rejection showed Ln BNP to be associated with rejection (HR 2.22; 95% CI 1.53-3.23, p<0.001). Conclusion: BNP continues to decrease in the 1 st 2 years after transplant. At rejection, BNP is elevated, and this test can be further developed to screen for rejection.

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