scholarly journals OP11.11: Spectrum of disorders of fetal cardiac rate and rhythm in anti‐Rho‐positive mothers: a single centre experience over one year

2019 ◽  
Vol 54 (S1) ◽  
pp. 123-123
Author(s):  
A. Sharma ◽  
V. Dadhwal ◽  
J.J. Chawla
Keyword(s):  
Cardiac Rate ◽  
Single Centre ◽  
Single Centre Experience ◽  
One Year

scholarly journals Efficiency and safety of one-year anti-TNF-α treatment in Crohn’s disease: a Polish single-centre experience

2020 ◽  
Vol 15 (2) ◽  
pp. 156-160 ◽  
Author(s):  
Marcin Sochal ◽  
Monika Krzywdzińska ◽  
Agata Gabryelska ◽  
Renata Talar-Wojnarowska ◽  
Ewa Małecka-Panas
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Single Centre ◽  
Tnf Α ◽  
Single Centre Experience ◽  
One Year

Stereotactic Radiosurgery for Brain Oligometastases: a One-year Single Centre Experience

2018 ◽  
Vol 30 (6) ◽  
pp. e64
Author(s):  
J. Ho ◽  
M. O'Cathail ◽  
R. Clements ◽  
K. Foweraker ◽  
M. Griffin ◽  
...  
Keyword(s):  
Stereotactic Radiosurgery ◽  
Single Centre ◽  
Single Centre Experience ◽  
One Year

scholarly journals COVID-19 Infection in Kidney Transplant Patients: An Italian One Year Single Centre Experience

Pathogens ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 964
Author(s):  
Mariarosaria Campise ◽  
Carlo Maria Alfieri ◽  
Marta Perego ◽  
Francesco Tamborini ◽  
Donata Cresseri ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Calcineurin Inhibitors ◽  
Kidney Injury ◽  
Single Centre ◽  
Lombardy Region ◽  
Transplant Patients ◽  
Single Centre Experience ◽  
Kidney Transplant Patients ◽  
Low Incidence ◽  
One Year

COVID-19 is a life-threatening infection among elderly patients, comorbid patients, or transplanted patients. Lombardy (region of Italy), accounts for 786,324 cases as of 21 April 2021. We retrospectively describe our single Centre experience in 82 adult kidney-transplant patients with COVID-19 infection during two pandemic outbreaks: 27 (first outbreak) and 65 (second outbreak). Thirty-seven patients were hospitalized (HP) and sixty-five were home managed (HM). Infection presented with fever (80%), cough (51%), and dyspnea (33%). HP were older (60 ± 11 vs. 50 ± 14 years, p = 0.001), had more severe respiratory symptoms (dyspnea 62.1%, p < 0.0001–cough 67% p = 0.008), and a longer length of disease (30 ± 28 vs. 21 ± 10, p = 0.04). The incidence of acute kidney injury (AKI) was 29.7% (p < 0.0001). Steroid dosage was increased in 66% of patients (p = 0.0003), while calcineurin inhibitors were reduced by up to one third in 45% of cases, p < 0.0001. Eleven patients died (13%). HM patients recovered completely without sequelae. In the overall cohort, AKI development (p = 0.006 OR 50.4 CI 95% 3.0–836) and age (p = 0.04 OR 1.1 CI 95% 1.0–1.2) were the most important factors influencing the probability of death during the infection. Although we report a relatively low incidence of infection (5.1%) the incidence of death is almost four times higher than it is in the general population.

scholarly journals P.006 Neural antibody testing for autoimmune encephalitis: A Canadian single-centre experience

2021 ◽  
Vol 48 (s3) ◽  
pp. S21-S21
Author(s):  
A Mirian ◽  
S McFadden ◽  
P Edmond ◽  
V Bhayana ◽  
L Yang ◽  
...  
Keyword(s):  
False Positive ◽  
Clinical Presentation ◽  
Clinical Phenotype ◽  
Autoimmune Encephalitis ◽  
Antibody Testing ◽  
Single Centre ◽  
Clinical Sensitivity ◽  
Single Centre Experience ◽  
One Year ◽  
Positive Results

Background: We reviewed our autoimmune encephalitis neural antibody testing using brain tissue indirect immunofluorescence (TIIF) and cell-based assays (CBAs) after one year. Methods: Samples were tested from March 2019–March 2020 by TIIF and CBA for anti-NMDAR, LGI1, CASPR2, AMPAR, GABA(B)R, DPPX, IgLON5 and GAD65. Weakly positive or positive CBA, with or without corresponding TIIF positivity, was reported positive. Clinical questionnaires were submitted for clinical-serological correlation. Patients with a compatible clinical phenotype and no more likely alternative diagnosis were classified as true-positives, while all others were flagged as possible false-positives. Results: Twenty of 373 patients (5.4%) had a positive neural antibody. All anti-LGI1 (N=4), GAD65 (N=4), and GABA(B)R (N=1) were classified as true-positives. In contrast, only 3/6 anti-CASPR2 and 3/5 anti-NMDAR were classified as true-positives. Among true-positives, 2/4 anti-LGI and 3/3 anti-CASPR2 were positive by CBA only. All possible false-positive results exhibited only weak serum staining by CBA, with negative serum TIIF and negative CSF CBA/TIIF (if available). Conclusions: Clinical sensitivity of CBA seems higher than TIIF for neural antibodies studied herein, but may come at some expense to clinical specificity. Among patients with weak serum staining by CBA, correlation with serum TIIF, CSF CBA/TIIF, and clinical presentation is recommended.

One-year follow-up after second-generation cryoballoon ablation for atrial fibrillation in a large cohort of patients: a single-centre experience

EP Europace ◽  
2015 ◽  
Vol 18 (7) ◽  
pp. 987-993 ◽  
Author(s):  
Ghazala Irfan ◽  
Carlo de Asmundis ◽  
Giacomo Mugnai ◽  
Jan Poelaert ◽  
Christian Verborgh ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Second Generation ◽  
Large Cohort ◽  
Cryoballoon Ablation ◽  
Single Centre ◽  
Single Centre Experience ◽  
One Year
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