scholarly journals COVID-19 Infection in Kidney Transplant Patients: An Italian One Year Single Centre Experience

Pathogens ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 964
Author(s):  
Mariarosaria Campise ◽  
Carlo Maria Alfieri ◽  
Marta Perego ◽  
Francesco Tamborini ◽  
Donata Cresseri ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Calcineurin Inhibitors ◽  
Kidney Injury ◽  
Single Centre ◽  
Lombardy Region ◽  
Transplant Patients ◽  
Single Centre Experience ◽  
Kidney Transplant Patients ◽  
Low Incidence ◽  
One Year

COVID-19 is a life-threatening infection among elderly patients, comorbid patients, or transplanted patients. Lombardy (region of Italy), accounts for 786,324 cases as of 21 April 2021. We retrospectively describe our single Centre experience in 82 adult kidney-transplant patients with COVID-19 infection during two pandemic outbreaks: 27 (first outbreak) and 65 (second outbreak). Thirty-seven patients were hospitalized (HP) and sixty-five were home managed (HM). Infection presented with fever (80%), cough (51%), and dyspnea (33%). HP were older (60 ± 11 vs. 50 ± 14 years, p = 0.001), had more severe respiratory symptoms (dyspnea 62.1%, p < 0.0001–cough 67% p = 0.008), and a longer length of disease (30 ± 28 vs. 21 ± 10, p = 0.04). The incidence of acute kidney injury (AKI) was 29.7% (p < 0.0001). Steroid dosage was increased in 66% of patients (p = 0.0003), while calcineurin inhibitors were reduced by up to one third in 45% of cases, p < 0.0001. Eleven patients died (13%). HM patients recovered completely without sequelae. In the overall cohort, AKI development (p = 0.006 OR 50.4 CI 95% 3.0–836) and age (p = 0.04 OR 1.1 CI 95% 1.0–1.2) were the most important factors influencing the probability of death during the infection. Although we report a relatively low incidence of infection (5.1%) the incidence of death is almost four times higher than it is in the general population.

C140: Technical aspects of double-J catheter use in post kidney transplant patients – 3 years single-centre experience

2014 ◽  
Vol 13 (6) ◽  
pp. e1324
Author(s):  
B.S. Sutkowski ◽  
E.B. Bres-Niewada ◽  
M.Ł. Łykowski ◽  
J.Z. Zajączkowska ◽  
T.M. Mutrynowski ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Single Centre ◽  
Technical Aspects ◽  
Transplant Patients ◽  
Single Centre Experience ◽  
Kidney Transplant Patients

scholarly journals A Systematic Review of COVID-19 Infection in Kidney Transplant Recipients: A Universal Effort to Preserve Patients’ Lives and Allografts

2020 ◽  
Vol 9 (9) ◽  
pp. 2986 ◽  
Author(s):  
Smaragdi Marinaki ◽  
Stathis Tsiakas ◽  
Maria Korogiannou ◽  
Konstantinos Grigorakos ◽  
Vassilios Papalois ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Distress Syndrome ◽  
Kidney Injury ◽  
Deceased Donor ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Male Predominance ◽  
Transplant Patients ◽  
Kidney Transplant Patients ◽  
The Mean

The coronavirus disease 2019 (COVID-19) pandemic has posed a significant challenge to physicians and healthcare systems worldwide. Evidence about kidney transplant (KTx) recipients is still limited. A systematic literature review was performed. We included 63 articles published from 1 January until 7 July 2020, reporting on 420 adult KTx recipients with confirmed COVID-19. The mean age of patients was 55 ± 15 years. There was a male predominance (67%). The majority (74%) were deceased donor recipients, and 23% were recently transplanted (<1 year). Most patients (88%) had at least one comorbidity, 29% had two, and 18% three. Ninety-three percent of cases were hospitalized. Among them, 30% were admitted to the intensive care unit, 45% developed acute respiratory distress syndrome, and 44% had acute kidney injury with 23% needing renal replacement therapy. From the hospitalized patients a total of 22% died, 59% were discharged, and 19% were still in hospital at the time of publication. Immunosuppression was reduced in 27%, discontinued in 31%, and remained unchanged in 5%. Hydroxychloroquine was administered to 78% of patients, antibiotics to 73%, and antivirals to 30% while 25% received corticosteroid boluses, 28% received anti-interleukin agents, and 8% were given immunoglobulin. The main finding of our analysis was that the incidence of COVID-19 among kidney transplant patients is not particularly high, but when they do get infected, this is related to significant morbidity and mortality.

Long-term Results of Conversion From Calcineurin Inhibitors to Sirolimus in 150 Maintenance Kidney Transplant Patients

2012 ◽  
Vol 10 (2) ◽  
pp. 110-118 ◽  
Author(s):  
Cyril Garrouste ◽  
Nassim Kamar ◽  
Céline Guilbeau-Frugier ◽  
Joëlle Guitard ◽  
Laure Esposito ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Calcineurin Inhibitors ◽  
Long Term Results ◽  
Transplant Patients ◽  
Kidney Transplant Patients

scholarly journals The impact of calcineurin inhibitors and mammalian target of rapamycininhibitors on anxiety and depression scores in kidney transplant patients

2016 ◽  
Vol 46 ◽  
pp. 1341-1347 ◽  
Author(s):  
Ebru GÖK OĞUZ ◽  
Gülay ULUSAL OKYAY ◽  
Hadim AKOĞLU ◽  
Güner KARAVELİ GÜRSOY ◽  
Zafer ERCAN ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Calcineurin Inhibitors ◽  
Anxiety And Depression ◽  
Transplant Patients ◽  
Kidney Transplant Patients ◽  
The Impact
Sign in / Sign up

Export Citation Format

Share Document