scholarly journals OP09.03: Prevalence of severe CNS abnormalities assessed by fetal MR among candidates for spina bifida prenatal surgery

2019 ◽  
Vol 54 (S1) ◽  
pp. 112-112
Author(s):  
L. Trigo ◽  
E. Eixarch ◽  
M. Aertsen ◽  
I. Bottura ◽  
M. Dalaqua ◽  
...  
Keyword(s):  
Spina Bifida ◽  
Fetal Mr ◽  
Prenatal Surgery

scholarly journals Towards Guideline-Based Management of Tethered Cord Syndrome in Spina Bifida: A Global Health Paradigm Shift in the Era of Prenatal Surgery

Neurospine ◽  
2019 ◽  
Vol 16 (4) ◽  
pp. 715-727 ◽  
Author(s):  
Viachaslau Bradko ◽  
Heidi Castillo ◽  
Shruthi Janardhan ◽  
Benny Dahl ◽  
Kellen Gandy ◽  
...  
Keyword(s):  
Spina Bifida ◽  
Global Health ◽  
Paradigm Shift ◽  
Tethered Cord ◽  
Tethered Cord Syndrome ◽  
Prenatal Surgery

scholarly journals Prenatal surgery for spina bifida: a therapeutic dilemma. Proceedings of the SHINE conference, Belfast

2017 ◽  
Vol 187 (3) ◽  
pp. 713-718 ◽  
Author(s):  
Mano Shanmuganathan ◽  
Deborah A. Sival ◽  
Kelly-Ann Eastwood ◽  
Katie Morris ◽  
Jacqueline Cartmill ◽  
...  
Keyword(s):  
Spina Bifida ◽  
Prenatal Surgery

336: Fetal MR spine findings and associated adverse outcomes in children with spina bifida

2009 ◽  
Vol 201 (6) ◽  
pp. S132-S133
Author(s):  
Tamara T. Chao ◽  
Jodi S. Dashe ◽  
Richard C. Adams ◽  
Amy Keefover-Hicks ◽  
Donald D. Mcintire ◽  
...  
Keyword(s):  
Spina Bifida ◽  
Adverse Outcomes ◽  
Fetal Mr

scholarly journals Impact of Brain Malformations on Neurodevelopmental Outcome in Children with a History of Prenatal Surgery for Open Spina Bifida

2021 ◽  
pp. 1-8
Author(s):  
David-Alexander Wille ◽  
Beth Padden ◽  
Ueli Moehrlen ◽  
Beatrice Latal ◽  
Sonja Schauer ◽  
...  
Keyword(s):  
Spina Bifida ◽  
Neurodevelopmental Outcome ◽  
Cognitive Outcome ◽  
Composite Score ◽  
Third Ventriculostomy ◽  
Ventricular Size ◽  
Brain Malformations ◽  
Motor Testing ◽  
Chiari Ii ◽  
Prenatal Surgery

<b><i>Introduction:</i></b> This retrospective study investigates brain malformations and their impact on neurodevelopmental outcome in children after prenatal surgery for spina bifida (SB). <b><i>Methods:</i></b> Sixty-one patients were included. On neonatal MRI, SB-associated brain malformations were assessed. Ventricular size, ventriculo-peritoneal shunt (VPS), and endoscopic third ventriculostomy (ETV) were also documented. Neurodevelopment was assessed with the Bayley-III and correlated with brain malformations, ventricular size, and VPS/ETV placement. <b><i>Results:</i></b> Chiari II malformation was detected in all patients. Corpus callosum (CC) abnormality was noted in 40%, heterotopies in 35%, and cerebellar parenchymal defects in 11%. 96% had ventriculomegaly; in 46%, VPS/ETV was performed. Cognitive and language testing yielded results in the low-average range (Bayley-III: Cognitive Composite Score 93.6, Language Composite Score 89.7), motor testing was below average (Motor Composite Score 77.4). CC abnormalities, heterotopies, and cerebellar defects were not associated with poorer Bayley-III scores, whereas patients with severe ventriculomegaly performed poorer in all subtests, significantly so for the language composite score. Patients requiring intervention for hydrocephalus had significantly lower scores in motor testing. <b><i>Discussion/Conclusion:</i></b> Additional brain malformations in open SB do not seem to have an impact on cognitive function at 2 years of age. Severe ventriculomegaly is a risk factor for poorer cognitive outcome; hydrocephalus surgery adds an additional risk for delayed motor function.

scholarly journals VP21.06: Functional neurodevelopment evidence in a case of Chiari II with prenatal surgery of open spina bifida

2020 ◽  
Vol 56 (S1) ◽  
pp. 145-145
Author(s):  
P.I. Cavoretto ◽  
M. Canini ◽  
M. Candiani ◽  
M. Caglioni ◽  
A. Falini ◽  
...  
Keyword(s):  
Spina Bifida ◽  
Chiari Ii ◽  
Open Spina Bifida ◽  
Prenatal Surgery

337: Fetal MR central nervous system findings and associated adverse outcomes in children with spina bifida

2009 ◽  
Vol 201 (6) ◽  
pp. S133
Author(s):  
Tamara T. Chao ◽  
Jodi S. Dashe ◽  
Richard C. Adams ◽  
Amy Keefover-Hicks ◽  
Donald D. Mcintire ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Spina Bifida ◽  
Adverse Outcomes ◽  
Fetal Mr
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