scholarly journals Effect of clomiphene citrate on endometrial thickness, ovulation, pregnancy and live birth in anovulatory women: systematic review and meta-analysis

2017 ◽  
Vol 51 (1) ◽  
pp. 64-76 ◽  
Author(s):  
M. A. Gadalla ◽  
S. Huang ◽  
R. Wang ◽  
R. J. Norman ◽  
S. A. Abdullah ◽  
...  
Keyword(s):  
Systematic Review ◽  
Live Birth ◽  
Endometrial Thickness ◽  
Meta Analysis ◽  
Clomiphene Citrate

scholarly journals GnRH agonist and hCG (dual trigger) versus hCG trigger for follicular maturation: a systematic review and meta-analysis of randomized trials

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Kai-Lun Hu ◽  
Siwen Wang ◽  
Xiaohang Ye ◽  
Dan Zhang ◽  
Sarah Hunt
Keyword(s):  
Systematic Review ◽  
Pregnancy Rate ◽  
Live Birth ◽  
Gnrh Agonist ◽  
Birth Rate ◽  
Randomized Trials ◽  
Meta Analysis ◽  
Live Birth Rate ◽  
Follicular Maturation ◽  
Hcg Trigger

Abstract Background Traditionally, final follicular maturation is triggered by a single bolus of human chorionic gonadotropin (hCG). This acts as a surrogate to the naturally occurring luteinizing hormone (LH) surge to induce luteinization of the granulosa cells, resumption of meiosis and final oocyte maturation. More recently, a bolus of gonadotropin-releasing hormone (GnRH) agonist in combination with hCG (dual trigger) has been suggested as an alternative regimen to achieve final follicular maturation. Methods This study was a systematic review and meta-analysis of randomized trials evaluating the effect of dual trigger versus hCG trigger for follicular maturation on pregnancy outcomes in women undergoing in vitro fertilization (IVF). The primary outcome was the live birth rate (LBR) per started cycle. Results A total of 1048 participants were included in the analysis, with 519 in the dual trigger group and 529 in the hCG trigger group. Dual trigger treatment was associated with a significantly higher LBR per started cycle compared with the hCG trigger treatment (risk ratio (RR) = 1.37 [1.07, 1.76], I2 = 0%, moderate evidence). There was a trend towards an increase in both ongoing pregnancy rate (RR = 1.34 [0.96, 1.89], I2 = 0%, low evidence) and implantation rate (RR = 1.31 [0.90, 1.91], I2 = 76%, low evidence) with dual trigger treatment compared with hCG trigger treatment. Dual trigger treatment was associated with a significant increase in clinical pregnancy rate (RR = 1.29 [1.10, 1.52], I2 = 13%, low evidence), number of oocytes collected (mean difference (MD) = 1.52 [0.59, 2.46), I2 = 53%, low evidence), number of mature oocytes collected (MD = 1.01 [0.43, 1.58], I2 = 18%, low evidence), number of fertilized oocytes (MD = 0.73 [0.16, 1.30], I2 = 7%, low evidence) and significantly more usable embryos (MD = 0.90 [0.42, 1.38], I2 = 0%, low evidence). Conclusion Dual trigger treatment with GnRH agonist and HCG is associated with an increased live birth rate compared with conventional hCG trigger. Trial registration CRD42020204452.

Endometrial Thickness in Women Undergoing IUI With Ovarian Stimulation. How Thick Is Too Thin? A Systematic Review and Meta-analysis

2017 ◽  
Vol 72 (8) ◽  
pp. 484-485
Author(s):  
N. S. Weiss ◽  
M. N. van Vliet ◽  
J. Limpens ◽  
P. G. A. Hompes ◽  
C. B. Lambalk ◽  
...  
Keyword(s):  
Systematic Review ◽  
Ovarian Stimulation ◽  
Endometrial Thickness ◽  
Meta Analysis

Live birth rates after transfer of equal number of blastocysts or cleavage-stage embryos in IVF. a systematic review and meta-analysis

2007 ◽  
Vol 88 ◽  
pp. S317
Author(s):  
E.G. Papanikolaou ◽  
E. Kolibianakis ◽  
C. Venetis ◽  
H. Tournaye ◽  
B. Tarlatzis ◽  
...  
Keyword(s):  
Systematic Review ◽  
Live Birth ◽  
Meta Analysis ◽  
Cleavage Stage ◽  
Birth Rates ◽  
Live Birth Rates

Letrozole versus clomiphene citrate in polycystic ovary syndrome: systematic review and meta-analysis

2015 ◽  
Vol 31 (12) ◽  
pp. 917-921 ◽  
Author(s):  
Matheus Roque ◽  
Ana C. I. Tostes ◽  
Marcello Valle ◽  
Marcos Sampaio ◽  
Selmo Geber
Keyword(s):  
Systematic Review ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Meta Analysis ◽  
Clomiphene Citrate ◽  
Ovary Syndrome

scholarly journals Endometrial thickness in women undergoing IUI with ovarian stimulation. How thick is too thin? A systematic review and meta-analysis

2017 ◽  
Vol 32 (5) ◽  
pp. 1009-1018 ◽  
Author(s):  
N.S. Weiss ◽  
M.N. van Vliet ◽  
J. Limpens ◽  
P.G.A. Hompes ◽  
C.B. Lambalk ◽  
...  
Keyword(s):  
Systematic Review ◽  
Ovarian Stimulation ◽  
Endometrial Thickness ◽  
Meta Analysis

scholarly journals Clomiphene Citrate for Men with Hypogonadism ‐ A Systematic Review & Meta‐analysis

Andrology ◽  
2021 ◽  
Author(s):  
M. Huijben ◽  
M.T.W.T Lock ◽  
V.F. Kemp ◽  
L.M.O. Kort ◽  
H.M.K Breda
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Clomiphene Citrate
Sign in / Sign up

Export Citation Format

Share Document