scholarly journals OP14.02: Ultrasound and Doppler evaluation at routine third trimester scan to detect late pregnancy (SGA) in adequate-for-gestational age (AGA) pregnancies

2015 ◽  
Vol 46 ◽  
pp. 93-94
Author(s):  
M.A. Parra-Saavedra ◽  
S. Triunfo ◽  
F. Crovetto ◽  
E. Gratacós ◽  
F. Figueras
Keyword(s):  
Gestational Age ◽  
Late Pregnancy ◽  
Third Trimester ◽  
Doppler Evaluation

scholarly journals OC20.06: Angiogenic factors versus Doppler evaluation in the third trimester for the identification of late-onset small-for-gestational age births

2014 ◽  
Vol 44 (S1) ◽  
pp. 47-48
Author(s):  
S. Triunfo ◽  
M. Parra-Saavedra ◽  
F. Crovetto ◽  
V. Rodriguez-Sureda ◽  
C. Dominguez ◽  
...  
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Late Onset ◽  
Angiogenic Factors ◽  
Third Trimester ◽  
The Third ◽  
Doppler Evaluation

scholarly journals Association Between Maternal Thyroid Hormones and Birth Weight at Early and Late Pregnancy

2019 ◽  
Vol 104 (12) ◽  
pp. 5853-5863 ◽  
Author(s):  
Chen Zhang ◽  
Xi Yang ◽  
Yong Zhang ◽  
Fei Guo ◽  
Shuai Yang ◽  
...  
Keyword(s):  
Birth Weight ◽  
Thyroid Hormones ◽  
Thyroid Function ◽  
Gestational Age ◽  
Late Pregnancy ◽  
First Trimester ◽  
Thyroid Peroxidase ◽  
Third Trimester ◽  
Increased Risk ◽  
Maternal Thyroid

AbstractContextPrevious studies suggest that maternal thyroid function affects fetal growth, but the association between combined thyroid hormones from early to late pregnancy and newborn birth weight remains unknown.ObjectiveTo explore the association of maternal thyroid function during early and late pregnancy with birth weight.DesignA large prospective cohort study of a Chinese population.SettingThis study recruited pregnant women who underwent first-trimester prenatal screenings at the International Peace Maternity and Child Health Hospital between January 2013 and December 2016.ParticipantsThis study enrolled 46,186 mothers in whom TSH, free thyroxine (FT4), T3, and thyroid peroxidase antibody concentrations were measured in the first and third trimesters and in whom data on birth weight were available.Main Outcome MeasuresBirth weight, small for gestational age, large for gestational age (LGA).ResultsA higher TSH or FT4 concentration, or a lower T3 concentration, during the first or third trimester was associated with a lower birth weight. The lowest percentiles of maternal FT4 (FT4 < 2.5th percentile) in both trimesters were associated with a 0.34-SD higher birth weight. The effect estimates were greater in those in the first trimester (0.23 SD) or in the third trimester (0.17 SD). The association of maternal TSH and FT4 with birth weight differed according to fetal sex.ConclusionsPersistently low FT4 concentrations throughout pregnancy were associated with higher birth weight and an increased risk of LGA. Based on these findings, we recommend monitoring mildly altered concentrations of thyroid hormone throughout pregnancy.

Comparative assessment of informational content of the equations of F.P. Hadlock and the computer program of V.N. Demidov in determination of term of gestation and fetal weight in the III trimester of gestation

2017 ◽  
Author(s):  
E.A. Derkach , O.I. Guseva
Keyword(s):  
Computer Program ◽  
High Precision ◽  
Gestational Age ◽  
Computer Programs ◽  
Comparative Assessment ◽  
Fetal Weight ◽  
Informational Content ◽  
Third Trimester ◽  
The Third

Objectives: to compare the accuracy of equations F.P. Hadlock and computer programs by V.N. Demidov in determining gestational age and fetal weight in the third trimester of gestation. Materials: 328 patients in terms 36–42 weeks of gestation are examined. Ultrasonography was performed in 0–5 days prior to childbirth. Results: it is established that the average mistake in determination of term of pregnancy when using the equation of F.P. Hadlock made 12,5 days, the computer program of V.N. Demidov – 4,4 days (distinction 2,8 times). The mistake within 4 days, when using the equation of F.P. Hadlock has met on average in 23,1 % of observations, the computer program of V.N. Demidov — 65,9 % (difference in 2,9 times). The mistake more than 10 days, took place respectively in 51,7 and 8,2 % (distinction by 6,3 times). At a comparative assessment of size of a mistake in determination of fetal mass it is established that when using the equation of F.P. Hadlock it has averaged 281,0 g, at application of the computer program of V.N. Demidov — 182,5 g (distinction of 54 %). The small mistake in the mass of a fetus which isn't exceeding 200 g at application of the equation of F.P. Hadlock has met in 48,1 % of cases and the computer program of V.N. Demidov — 64,0 % (distinction of 33,1 %). The mistake exceeding 500 g has been stated in 18 % (F.P. Hadlock) and 4,3 % (V.N. Demidov) respectively (distinction 4,2 times). Conclusions: the computer program of V.N. Demidov has high precision in determination of term of a gestation and mass of a fetus in the III pregnancy.

The sFlt-1 to PlGF Ratio in Pregnant Women with Rheumatoid Arthritis: Impact of Disease Activity and Sulfasalazine Use

Rheumatology ◽  
2021 ◽  
Author(s):  
Rugina I Neuman ◽  
Hieronymus T W Smeele ◽  
A H Jan Danser ◽  
Radboud J E M Dolhain ◽  
Willy Visser
Keyword(s):  
Rheumatoid Arthritis ◽  
Cohort Study ◽  
Disease Activity ◽  
Pregnant Women ◽  
Gestational Age ◽  
Third Trimester ◽  
Low Disease Activity ◽  
The Third ◽  
Observational Prospective Cohort Study ◽  
Plgf Ratio

Abstract Objectives An elevated sFlt-1/PlGF-ratio has been validated as a significant predictor of preeclampsia, but has not been established in women with rheumatoid arthritis (RA). We explored whether the sFlt-1/PlGF-ratio could be altered due to disease activity in RA, and could be applied in this population to predict preeclampsia. Since sulfasalazine has been suggested to improve the angiogenic imbalance in preeclampsia, we also aimed to examine whether sulfasalazine could affect sFlt-1 or PlGF levels. Methods Making use of a nationwide, observational, prospective cohort study on pregnant women with RA, sFlt-1 and PlGF were measured in the third trimester. A total of 221 women, aged 21–42 years, were included, with a median gestational age of 30 + 3 weeks. Results No differences in sFlt-1 or PlGF were observed between women with high, intermediate or low disease activity (p= 0.07 and p= 0.41), whereas sFlt-1 and PlGF did not correlate with DAS28-CRP score (r=-0.01 and r=-0.05, respectively). Four (2%) women with a sFlt-1/PlGF-ratio ≤38 developed preeclampsia in comparison to three (43%) women with a ratio &gt; 38, corresponding to a negative predictive value of 98.1%. Sulfasalazine users (n = 57) did not show altered levels of sFlt-1 or PlGF in comparison to non-sulfasalazine users (n = 164, p= 0.91 and p= 0.11). Conclusion Our study shows that in pregnant women with RA, the sFlt-1/PlGF-ratio is not altered due to disease activity and a cut-off ≤38 can be used to exclude preeclampsia. Additionally, sulfasalazine use did not affect sFlt-1 or PlGF levels in this population.

Predicting Perinatal Outcome from Prenatal Ultrasound Characteristics in Pregnancies Complicated by Gastroschisis

2015 ◽  
Vol 39 (4) ◽  
pp. 279-286 ◽  
Author(s):  
Gabriella Martillotti ◽  
Isabelle Boucoiran ◽  
Amélie Damphousse ◽  
Andrée Grignon ◽  
Eric Dubé ◽  
...  
Keyword(s):  
Gestational Age ◽  
Predictive Value ◽  
Intrauterine Growth Restriction ◽  
Adverse Outcome ◽  
Prenatal Ultrasound ◽  
Intestinal Lumen ◽  
Third Trimester ◽  
Mesenteric Circulation ◽  
Intrauterine Growth ◽  
Bowel Dilatation

Introduction: The objective of the study was to establish the predictive value of prenatal ultrasound markers for complex gastroschisis (GS) in the first 10 days of life. Material and Methods: In this retrospective cohort study over 11 years (2000-2011) of 117 GS cases, the following prenatal ultrasound signs were analyzed at the last second- and third-trimester ultrasounds: intrauterine growth restriction, intra-abdominal bowel dilatation (IABD) adjusted for gestational age, extra-abdominal bowel dilatation (EABD) ≥25 mm, stomach dilatation, stomach herniation, perturbed mesenteric circulation, absence of bowel lumen and echogenic dilated bowel loops (EDBL). Results: Among 114 live births, 16 newborns had complex GS (14.0%). Death was seen in 16 cases (13.7%): 3 intrauterine fetal deaths, 9 complex GS and 4 simple GS. Second-trimester markers had limited predictive value. Third-trimester IABD, EABD, EDBL, absence of intestinal lumen and perturbed mesenteric circulation were statistically associated with complex GS and death. IABD was able to predict complex GS with a sensitivity of 50%, a specificity of 91%, a positive predictive value of 47% and a negative predictive value of 92%. Discussion: Third-trimester IABD adjusted for gestational age appears to be the prenatal ultrasound marker most strongly associated with adverse outcome in GS.

CHOREA GRAVIDARUM: A RARE CASE REPORT

2021 ◽  
pp. 71-72
Author(s):  
Aswini Viswanadh ◽  
Sujata Singh ◽  
Vinnisa N. V
Keyword(s):  
Case Report ◽  
Family History ◽  
Gestational Age ◽  
Postpartum Period ◽  
Rare Case ◽  
Third Trimester ◽  
Detailed Evaluation ◽  
Rare Case Report

Chorea gravidarum is the term given to chorea occurring during pregnancy. Here, we report a case of 24 year old primigravida at gestational age 38 weeks 3days ,without any signicant past & family history who presented with chorea gravidarum for the rst time in third trimester. On detailed evaluation no etiology was identied. On follow up in postpartum period, her choreiform movements have reduced in intensity, but is still persisting pointing towards an idiopathic origin.

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