scholarly journals OP03.07: Borderline ovarian tumors and frozen section: role of preoperative He4 and ROMA score to increase frozen section accuracy

2015 ◽  
Vol 46 ◽  
pp. 61-61
Author(s):  
S. Gizzo ◽  
M. Noventa ◽  
A. Vitagliano ◽  
M. Quaranta ◽  
R. Venturella ◽  
...  
Keyword(s):  
Frozen Section ◽  
Ovarian Tumors ◽  
Borderline Ovarian Tumors

scholarly journals The value of frozen section evaluation in the management of borderline ovarian tumors

2011 ◽  
Vol 7 (4) ◽  
pp. 416 ◽  
Author(s):  
Emre Gultekin ◽  
Basak Cingillioglu ◽  
Muzaffer Sanci ◽  
OzgeElmastas Gultekin ◽  
Sevil Sayhan ◽  
...  
Keyword(s):  
Frozen Section ◽  
Ovarian Tumors ◽  
Borderline Ovarian Tumors ◽  
Section Evaluation

Frozen section in borderline ovarian tumors: is it reliable?

2014 ◽  
Vol 181 ◽  
pp. 115-118 ◽  
Author(s):  
Isin Ureyen ◽  
Taner Turan ◽  
Derya Akdag Cirik ◽  
Tolga Tasci ◽  
Nurettin Boran ◽  
...  
Keyword(s):  
Frozen Section ◽  
Ovarian Tumors ◽  
Borderline Ovarian Tumors

Role of Intraoperative Frozen Section in the Diagnosis of Ovarian Tumors: Experience at Gujarat Cancer and Research Institute

2018 ◽  
Vol 16 (4) ◽  
Author(s):  
Ruchi S. Arora ◽  
Shilpa M. Patel ◽  
Pariseema S. Dave ◽  
Bijal M. Patel ◽  
Chetana D. Parikh ◽  
...  
Keyword(s):  
Frozen Section ◽  
Ovarian Tumors ◽  
Intraoperative Frozen Section ◽  
Research Institute

scholarly journals Borderline Ovarian Tumors and Diagnostic Dilemma of Intraoperative Diagnosis: Could Preoperative He4 Assay and ROMA Score Assessment Increase the Frozen Section Accuracy? A Multicenter Case-Control Study

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Salvatore Gizzo ◽  
Roberto Berretta ◽  
Stefania Di Gangi ◽  
Maria Guido ◽  
Giuliano Carlo Zanni ◽  
...  
Keyword(s):  
Frozen Section ◽  
Menopausal Status ◽  
Laparoscopic Approach ◽  
Preoperative Assessment ◽  
Figo Stage ◽  
Serum Markers ◽  
Ovarian Tumors ◽  
Diagnostic Dilemma ◽  
Additional Information ◽  
Borderline Ovarian Tumors

The aim of our study was to assess the value of a preoperative He4-serum-assay and ROMA-score assessment in improving the accuracy of frozen section histology in the diagnosis of borderline ovarian tumors (BOT). 113 women presenting with a unilateral ovarian mass diagnosed as serous/mucinous BOT at frozen-section-histology (FS) and/or confirmed on final pathology were recruited. Pathologists were informed of the results of preoperative clinical/instrumental assessment of all patients. For Group_A patients, additional information regarding He4, CA125, and ROMA score was available (in Group_B only CA125 was known). The comparison between Group A and Group B in terms of FS accuracy, demonstrated a consensual diagnosis in 62.8% versus 58.6% (P: n.s.), underdiagnosis in 25.6% versus 41.4% (P<0.05), and overdiagnosis in 11.6% versus 0% (P<0.01). Low FS diagnostic accuracy was associated with menopausal status (OR: 2.13), laparoscopic approach (OR: 2.18), mucinous histotype (OR: 2.23), low grading (OR: 1.30), and FIGO stage I (OR: 2.53). Ultrasound detection of papillae (OR: 0.29), septa (OR: 0.39), atypical vascularization (OR: 0.34), serum He4 assay (OR: 0.39), and ROMA score assessment (OR: 0.44) decreased the probability of underdiagnosis. A combined preoperative assessment through serum markers and ultrasonographic features may potentially reduce the risk of underdiagnosis of BOTs on FS while likely increasing the concomitant incidence of false-positive events.

Surgical management of borderline ovarian tumors: The role of fertility-sparing surgery

2009 ◽  
Vol 113 (1) ◽  
pp. 75-82 ◽  
Author(s):  
Jeong-Yeol Park ◽  
Dae-Yeon Kim ◽  
Jong-Hyeok Kim ◽  
Yong-Man Kim ◽  
Young-Tak Kim ◽  
...  
Keyword(s):  
Surgical Management ◽  
Ovarian Tumors ◽  
Borderline Ovarian Tumors ◽  
Fertility Sparing Surgery ◽  
Fertility Sparing

scholarly journals Role of intraoperative frozen section in the diagnosis of ovarian tumors: Experience at Gujarat Cancer and Research Institute

2016 ◽  
Author(s):  
Ruchi Arora
Keyword(s):  
Surgical Management ◽  
Ovarian Neoplasms ◽  
Frozen Section ◽  
Ovarian Tumors ◽  
Borderline Tumors ◽  
Intraoperative Frozen Section ◽  
Histopathologic Diagnosis ◽  
Frozen Section Diagnosis ◽  
Line Of Therapy

Background: The surgical management of ovarian tumors depends on their correct categorization as benign, borderline or malignant. Ovarian neoplasms are an important cause of morbidity and mortality in women. This study was undertaken to evaluate the accuracy of intra-operative frozen section in the diagnosis of various categories of ovarian neoplasms. Methods: Intraoperative frozen section diagnosis was retrospectively evaluated in 125 patients with suspected ovarian neoplasms who underwent surgery as primary line of therapy at our institution. This was compared with the final histopathologic diagnosis on paraffin sections. Results: In 125 patients frozen section report had a sensitivity of 100%, 95.55% and 50% for benign, malignant and borderline tumors respectively. The corresponding specificities were 92.45%, 98.75% and 99.14% respectively. The overall accuracy of frozen section diagnosis was 95.2%. The majority of cases of disagreement were in the mucinous and borderline tumors. Conclusion: Intraoperative frozen section has high accuracy in the diagnosis of suspected ovarian neoplasms. It is a valuable tool to guide the surgical management of these patients and should be routinely used in all major oncology centers.

The role of intraoperative frozen section analysis in the choice of surgical strategy for ovarian tumors

2020 ◽  
Vol 9_2020 ◽  
pp. 120-128
Author(s):  
Nosova Yu.V. Nosova ◽  
Solopova A.E. Solopova ◽  
Asaturova A.V. Asaturova ◽  
Tregubova A.V. Tregubova ◽  
Kometova V.V. Kometova ◽  
...  
Keyword(s):  
Frozen Section ◽  
Ovarian Tumors ◽  
Surgical Strategy ◽  
Intraoperative Frozen Section ◽  
Frozen Section Analysis ◽  
Section Analysis

Accuracy of frozen section diagnosis in ovarian tumors: Is there a change in the course of time?

2003 ◽  
Vol 13 (5) ◽  
pp. 593-597 ◽  
Author(s):  
M. Gol ◽  
A. Baloglu ◽  
S. Yigit ◽  
M. Dogan ◽  
Ç. Aydin ◽  
...  
Keyword(s):  
Frozen Section ◽  
Correct Diagnosis ◽  
False Negative ◽  
Ovarian Tumors ◽  
Borderline Ovarian Tumors ◽  
Frozen Section Examination ◽  
Benign Ovarian Tumor ◽  
Frozen Section Diagnosis ◽  
Accuracy Rates ◽  
Higher Sensitivity

A retrospective study of 222 ovarian biopsy results between January 1, 2000 and August 31, 2002 was examined to determine the accuracy of frozen section diagnosis. In addition we reviewed all previous studies that examined the accuracy rates of frozen section diagnosis in ovarian tumors. Histopathologic examination results of frozen section biopsies were concordant with paraffin diagnosis in 92% of all cases. The sensitivity rates for benign, malignant, and borderline ovarian tumors were 98%, 88.7%, and 61%, respectively. There were five (2.2%) false-positive (overdiagnosed), and 13 (5.4%) false-negative (underdiagnosed) patients in frozen section examination. Frozen section examination of mucinous tumors showed higher underdiagnosis rates (20%). Review of previous studies showed no significant variation in accuracy rates of frozen section diagnosis for benign and malignant ovarian tumors, in relation with time. We found low accuracy rates for borderline ovarian tumors which was similar with the previous studies. Hovewer, there were consistent and relatively higher sensitivity rates for borderline ovarian tumors in the recent studies. As a result, we conclude that frozen section evaluation in identifying a malignant or benign ovarian tumor is accurate enough for the correct diagnosis. Since accuracy rates for borderline ovarian tumors are low, we should have more improvement in the correct diagnosis.

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