scholarly journals Transvaginal ultrasound assessment of myometrial and cervical stromal invasion in women with endometrial cancer: interobserver reproducibility among ultrasound experts and gynecologists

2015 ◽  
Vol 45 (4) ◽  
pp. 476-482 ◽  
Author(s):  
L. S. E. Eriksson ◽  
P. G. Lindqvist ◽  
A. Flöter Rådestad ◽  
M. Dueholm ◽  
D. Fischerova ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Transvaginal Ultrasound ◽  
Stromal Invasion ◽  
Interobserver Reproducibility ◽  
Ultrasound Assessment ◽  
Cervical Stromal Invasion

scholarly journals Association of Abnormal Pap Smear with Occult Cervical Stromal Invasion in Patients with Endometrial Cancer

2019 ◽  
Vol 20 (9) ◽  
pp. 2847-2850
Author(s):  
Kewalin Khumthong ◽  
Apiwat Aue-Aungkul ◽  
Pilaiwan Kleebkaow ◽  
Bandit Chumworathayi ◽  
Amornrat Temtanakitpaisan ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Pap Smear ◽  
Stromal Invasion ◽  
Cervical Stromal Invasion

Cervical Stromal Invasion Predicting Survival in Endometrial Cancer

2010 ◽  
Vol 116 (5) ◽  
pp. 1035-1041 ◽  
Author(s):  
J. Stuart Ferriss ◽  
William Brix ◽  
Rosemary Tambouret ◽  
Christopher P. DeSimone ◽  
Mark Stoler ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Stromal Invasion ◽  
Cervical Stromal Invasion

Vaginal brachytherapy alone for patients with Stage II endometrial cancer with inner half cervical stromal invasion

Brachytherapy ◽  
2019 ◽  
Vol 18 (5) ◽  
pp. 606-611 ◽  
Author(s):  
Elizabeth A. Barnes ◽  
Carlos Parra-Herran ◽  
Kevin Martell ◽  
Lisa Barbera ◽  
Amandeep Taggar ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Stage Ii ◽  
Stromal Invasion ◽  
Cervical Stromal Invasion

scholarly journals A Nomogram Model Involving Immunohistochemical Markers for Predicting the Recurrence of Stage I-II Endometrial Cancer

2021 ◽  
Vol 10 ◽  
Author(s):  
Peng Jiang ◽  
Mingzhu Jia ◽  
Jing Hu ◽  
Zhen Huang ◽  
Ying Deng ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Validation Cohort ◽  
Myometrial Invasion ◽  
Stage I ◽  
Stromal Invasion ◽  
Training Cohort ◽  
Immunohistochemical Markers ◽  
Cervical Stromal Invasion ◽  
Classical Parameters ◽  
Medical University

BackgroundThe purpose of this study was to establish a nomogram combining classical parameters and immunohistochemical markers to predict the recurrence of patients with stage I-II endometrial cancer (EC).Methods419 patients with stage I-II endometrial cancer who received primary surgical treatment at the First Affiliated Hospital of Chongqing Medical University were involved in this study as a training cohort. Univariate and multivariate Cox regression analysis of screening prognostic factors were performed in the training cohort to develop a nomogram model, which was further validated in 248 patients (validation cohort) from the Second Affiliated Hospital of Chongqing Medical University. The calibration curve was used for internal and external verification of the model, and the C-index was used for comparison among different models.ResultsThere were 51 recurrent cases in the training cohort while 31 cases in the validation cohort. Univariate analysis showed that age, histological type, histological grade, myometrial invasion, cervical stromal invasion, postoperative adjuvant treatment, and four immunohistochemical makers (Ki67, estrogen receptor, progesterone receptor, P53) were the related factors for recurrence of EC. Multivariate analysis demonstrated that histological type (P = 0.029), myometrial invasion (P = 0.003), cervical stromal invasion (P = 0.001), Ki67 (P < 0.001), ER (P = 0.009) and P53 expression (P = 0.041) were statistically correlated with recurrence of EC. Recurrence-free survival was better predicted by the proposed nomogram with a C-index of 0.832 (95% CI, 0.752–0.912) in the training cohort, and the validation set confirmed the finding with a C-index of 0.861 (95% CI, 0.755–0.967).ConclusionThe nomogram model combining classical parameters and immunohistochemical markers can better predict the recurrence in patients with FIGO stage I-II EC.

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