Endometrial vascularity is lower in pregnancies with pregnancy-induced hypertension or small-for-gestational-age fetus in live birth afterin-vitrofertilization

2014 ◽  
Vol 44 (4) ◽  
pp. 455-460 ◽  
Author(s):  
C. W. S. Lai ◽  
S. S. F. Yung ◽  
E. H. Y. Ng
Keyword(s):  
Live Birth ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Pregnancy Induced Hypertension ◽  
Induced Hypertension ◽  
Endometrial Vascularity

scholarly journals Risk of small for gestational age babies in preterm delivery due to pregnancy-induced hypertension

2019 ◽  
Vol 28 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Rima Irwinda ◽  
Budi Iman Santoso ◽  
Raymond Surya ◽  
Lidia Firmiaty Nembo
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Preterm Births ◽  
Secondary Data ◽  
Large For Gestational Age ◽  
Fisher Exact Test ◽  
Pregnancy Induced Hypertension ◽  
Exact Test ◽  
Induced Hypertension ◽  
The Impact

BACKGROUND Pregnancy-induced hypertension (PIH) causes high maternal morbidity and mortality worldwide. This study aims to assess the impact of PIH on fetal growth according to gestational age in preterm deliveries.METHODS A prospective cohort study using secondary data was undertaken in Ende District, East Nusa Tenggara, Indonesia from September 2014 to August 2015. The t-test was performed to compare mean birth weight based on gestational week between normotensive and PIH women, continued by linear regression. The chi-square or Fisher exact test was also conducted to determine the probability of birthing small for the gestational age (SGA) and large for gestational age (LGA) babies between normotensive and PIH women.RESULTS A total of 1,673 deliveries were recorded in Ende Hospital over the 1-year study period, among which 182 cases involved preterm births. The PIH group had lower birth weight than normotensive women at each gestational age starting from 32–35 weeks (p=0.004; 95% CI 150.84–771.36). Normotensive women at gestational ages of 32 (p=0.05; 95% CI 0.01–0.83), 34 (p=0.37; 95% CI 0.01–4.12), and 36 (p=0.31; 95% CI 0.02–2.95) weeks had a lower risk of birthing SGA babies than PIH women; LGA babies were recorded at gestational ages of 33 (p=1.00; 95% CI 0.07–37.73) and 35 (p=0.31; 95% CI 0.34–63.07) weeks.CONCLUSIONS Poor perfusion of the uteroplacental is one of the reasons behind intrauterine growth restriction, which results in SGA babies born to PIH women.

scholarly journals Dengue during pregnancy and live birth outcomes: a cohort of linked data from Brazil

BMJ Open ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. e023529 ◽  
Author(s):  
Enny S Paixão ◽  
Oona M Campbell ◽  
Maria Gloria Teixeira ◽  
Maria CN Costa ◽  
Katie Harron ◽  
...  
Keyword(s):  
Birth Weight ◽  
Preterm Birth ◽  
Low Birth Weight ◽  
Birth Outcomes ◽  
Live Birth ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Severe Dengue ◽  
Maternal Risk ◽  
Increased Risk

ObjectivesDengue is the most common viral mosquito-borne disease, and women of reproductive age who live in or travel to endemic areas are at risk. Little is known about the effects of dengue during pregnancy on birth outcomes. The objective of this study is to examine the effect of maternal dengue severity on live birth outcomes.Design and settingWe conducted a population-based cohort study using routinely collected Brazilian data from 2006 to 2012.ParticipatingWe linked birth registration records and dengue registration records to identify women with and without dengue during pregnancy. Using multinomial logistic regression and Firth method, we estimated risk and ORs for preterm birth (<37 weeks’ gestation), low birth weight (<2500 g) and small for gestational age (<10thcentile). We also investigated the effect of time between the onset of the disease and each outcome.ResultsWe included 16 738 000 live births. Dengue haemorrhagic fever was associated with preterm birth (OR=2.4; 95% CI 1.3 to 4.4) and low birth weight (OR=2.1; 95% CI 1.1 to 4.0), but there was no evidence of effect for small for gestational age (OR=2.1; 95% CI 0.4 to 12.2). The magnitude of the effects was higher in the acute disease period.ConclusionThis study showed an increased risk of adverse birth outcomes in women with severe dengue during pregnancy. Medical intervention to mitigate maternal risk during severe acute dengue episodes may improve outcomes for infants born to exposed mothers.

scholarly journals PREGNANCY INDUCED HYPERTENSION AND NEONATAL GROWTH

2019 ◽  
Vol 34 (4) ◽  
pp. 915-919
Author(s):  
Elizabeta Zisovska ◽  
Lidija Madzovska ◽  
Marija Dimitrovska Ivanova
Keyword(s):  
Birth Weight ◽  
Fetal Growth ◽  
Gestational Age ◽  
White Blood Cells ◽  
Infant Growth ◽  
Late Preterm ◽  
Control Group ◽  
Pregnancy Induced Hypertension ◽  
Gynecology And Obstetrics ◽  
Induced Hypertension

Pregnancy-induced hypertension (PIH), especially preeclampsia, is a major cause of maternal and perinatal morbidity and mortality worldwide. The impact of PIH on birth outcomes has not been extensively studied. PIH has been confirmed to increase significantly the risk of low birth weight by both increasing preterm birth as well as reducing fetal growth. Low birth weight or IUGR babies have been associated with the occurrence of several chronic diseases in later life. However, to date, there have been few studies on the effects of PIH on infant growth and neonatal wellbeing. The purpose of this study was to evaluate the fetal growth and wellbeing of newborns born of mothers with confirmed pregnancy induced hypertension.Material and methods: This was prospective opservational study during the period of the last year, 1st of July 2018 up to the end of June 2019 conducted at the University Clinic for Gynecology and Obstetrics in Skopje. As pregnancy induced hypertension is defined the condition of blood pressure equal to or greater than 130/90 mmHg on more than two occasions greater than six hours apart without proteinuria after 21 weeks of gestation. All other more severe conditions are defined as pre-eclampsia or eclampsia. As outcome was considered the birth weight, gestational age and white blood cells count. IUGR was defined as birth weight below the tenth percentile of expected weight for gestational age. Also maternal age and BMI were considered as conjoined risk factor for the birth weight. Results: In this study, 4726 newborns were born at the University Clinic for Gynecology and Obstetrics, and for analysis were considered 4273 newborns who were late preterm (35 and 36 gestational weeks) or term newborns. Two groups were evaluated: control group of 200 consecutively born newborns (late preterm and term) of healthy mothers and 100 newborns (late preterm and term) consecutively born of mothers with confirmed diagnosis of PIH, which constituted the study group. Within the control group, the proportion of Small for Gestational Age-SGA was 6,3%, and in the group of mothers with PIH was 9,5% (p<0,05). The maternal mean age of the hypertensive mothers was (32.8±5.0) years while that of normotensive mothers was (26.6±3.7) years, and there was not statistical significance (p>0.05). The Body Mass Index was higher in hypertensive mothers, compared to the healthy mothers (31,3±2.02 vs. 27.8±2.8). The mean gestational age of the study group was (35.8±1.8) weeks compared to that in control group (37.4±1.2) weeks. The number of White Blood Cells (WBC) count in newborns of hypertensive mothers was 21.4±5.3x109/L compared with the control group, 18.5±3.12x109/L (p=0.005). Neonatal thrombocytopenia was found in 32% of neonates of preeclamptic mothers while it's found only in 9.5% of neonates in control group p<0,002. Discussion: The limitation of this study was the lack of data about maternal smoking, life style, etc. There is limited number of studies examining the correlation between fetal growth and PIH, and every information is of great value. The fact is that this condition can progress in more severe degree of hypertension and deleterious effects on the mother itself and on her child, if not treated on time. Conclusion: A change in infant growth of the IUGR baby itself (e.g. catch-up growth) such as in the critical early infant period may also have long-term effects on health later in life, and this change of postpartum growth may be influenced by PIH. Therefore, it is important to study postpartum infant growth patterns of babies born to mothers with PIH, and to determine if there are differences in infant growth between babies with and those without IUGR. And, the most important action is to monitor and treat pregnancy induced hypertension and prevent more severe condition of pre-eclampsia.

The impact of pregnancy-induced hypertension on birth weight by gestational age

2001 ◽  
Vol 15 (4) ◽  
pp. A37-A37
Author(s):  
X Xiong ◽  
Nn Demianczuk ◽  
Ld Saunders ◽  
Fl Wang ◽  
Wd Fraser
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Pregnancy Induced Hypertension ◽  
Induced Hypertension ◽  
The Impact

scholarly journals Neonatal Outcome of Antenatal Mothers with Pregnancy Induced Hypertension in Antenatal Ward of Kathmandu Medical College and Teaching Hospital

2018 ◽  
Vol 2 (3) ◽  
pp. 255-259
Author(s):  
Santoshi Shrestha Pradhan ◽  
Sabitra Paudel ◽  
Puspa Parajuli ◽  
Bina Rana Khagi
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Apgar Score ◽  
Neonatal Death ◽  
Neonatal Outcome ◽  
Pregnancy Induced Hypertension ◽  
Perinatal Morbidity ◽  
Medical College ◽  
Induced Hypertension ◽  
Perinatal Management

Introduction: Hypertensive disorders seem to complicated in approximately 5-15% of pregnancies. Pregnancy induced hypertension (PIH) increases the risk of maternal and perinatal morbidity and mortality.Objective: To assess the neonatal outcome and to identify the association between the demographic variables and outcome of Pregnancy Induced Hypertension in antenatal ward of Kathmandu Medical College and Teaching Hospital.Methodology: Prospective study design was conducted for the study in Obstetrics ward of Kathmandu Medical College Teaching Hospital. The population was the 100 antenatal mothers with pregnancy induced hypertension admitted in antenatal ward and purposive convenient sampling technique was used to collect the data. The structured questionnaire was designed and the data was collected through interview technique from 1st February 2014 to 10 March 2016. The collected data was analyzed using SPSS programme.Results: Regarding neonatal outcome the findings of the study showed that most of the babies 83% had normal weight. The most of the babies 82% had adequate for gestational age. Regarding Apgar score half of the babies 50% scored mild asphyxia at the first minute whereas most of the babies 93% scored no asphyxia at five minutes after delivery. Regarding perinatal outcome 13% babies were delivered premature, 7% had birth asphyxia, 5% were born with low birth weight and stillbirth whereas only 1% had early neonatal death. The present study revealed that there was significant association between gestational age of delivery and Apgar score at 5 minutes and there was significant association between age and perinatal management outcome, gestational age of delivery and perinatal morbidity management, grading of proteinuria and perinatal morbidity management, grading of oedema and perinatal management outcome regarding neonatal outcome of pregnancy induced hypertension.Conclusion: Pregnancy induced hypertension during pregnancy were associated with a higher risk of adverse neonatal outcomes. Women with pregnancy induced hypertension during pregnancy had a higher risk of emergency caesarean section, pre-term birth, neonatal death, low birth weight children and neonates with low Apgar score. Maternal and fetal morbidity and mortality can be reduced by early recognition and institutional management.Birat Journal of Health SciencesVol.2/No.3/Issue 4/Sep- Dec 2017, Page: 255-259

scholarly journals Severe Hypothyroidism Causing Pre-Eclampsia-Like Syndrome

2012 ◽  
Vol 2012 ◽  
pp. 1-2 ◽  
Author(s):  
Annalisa Inversetti ◽  
Audrey Serafini ◽  
Marco F. Manzoni ◽  
Anna Dolcetta Capuzzo ◽  
Luca Valsecchi ◽  
...  
Keyword(s):  
Gestational Age ◽  
Early Onset ◽  
Overt Hypothyroidism ◽  
Pregnancy Induced Hypertension ◽  
Correct Treatment ◽  
Induced Hypertension ◽  
Early Onset Preeclampsia

Objective.Analyzing and managing pre-eclampsia-like syndrome due to severe hypothyroidism.Methods.Presentation of a case of severe hypothyroidism due to Hashimoto’s syndrome, associated with a severe early-onset preeclampsia-like syndrome, managed in our Gynecology Department.Results.Severe pre-eclampsia led to miscarriage at 24 weeks of gestational age in a 42-year-old woman, although we attempted to correct hypothyroidism with increasing doses of levothyroxine and liothyronine sodium.Conclusion.Recognizing pre-eclampsia-like syndrome caused by overt hypothyroidism from other forms of pregnancy-induced hypertension is essential for choosing the correct treatment.

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