scholarly journals Perinatal morbidity and mortality in early-onset fetal growth restriction: cohort outcomes of the trial of randomized umbilical and fetal flow in Europe (TRUFFLE)

2013 ◽  
Vol 42 (4) ◽  
pp. 400-408 ◽  
Author(s):  
C. Lees ◽  
N. Marlow ◽  
B. Arabin ◽  
C. M. Bilardo ◽  
C. Brezinka ◽  
...  
2013 ◽  
Vol 92 (6) ◽  
pp. 656-661 ◽  
Author(s):  
Khalil Abdelrazzaq ◽  
Ahmet Özgür Yeniel ◽  
Ahmet Mete Ergenoglu ◽  
Nuri Yildirim ◽  
Fuat Akercan ◽  
...  

2021 ◽  
Vol 2 (2) ◽  
pp. 85-94
Author(s):  
Andrea Dall’Asta ◽  
Monica Minopoli ◽  
Tullio Ghi ◽  
Tiziana Frusca

Early fetal growth restriction (FGR) remains a challenging entity associated with an increased risk of perinatal morbidity and mortality as well as maternal complications. Significant variations in clinical practice have historically characterized the management of early FGR fetuses. Nevertheless, insights into diagnosis and management options have more recently emerged. The aim of this review is to summarize the available evidence on monitoring, delivery and outcome in early-onset FGR.


2021 ◽  
Vol 224 (2) ◽  
pp. S403
Author(s):  
Emily N. Flagler ◽  
Erin M. Cleary ◽  
Michelle R. Petrich ◽  
Emily A. Armstrong ◽  
Patricia K. Belle ◽  
...  

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
L. Ormesher ◽  
L. Warrander ◽  
Y. Liu ◽  
S. Thomas ◽  
L. Simcox ◽  
...  

AbstractAbnormal maternal serum biomarkers (AMSB), identified through the aneuploidy screening programme, are frequent incidental findings in pregnancy. They are associated with fetal growth restriction (FGR), but previous studies have not examined whether this association is with early-onset (< 34 weeks) or late-onset (> 34 weeks) FGR; as a result there is no consensus on management. The aims of this study were to determine the prevalence and phenotype of FGR in women with AMSB and test the predictive value of placental sonographic screening to predict early-onset FGR. 1196 pregnant women with AMSB underwent a 21–24 week “placental screen” comprising fetal and placental size, and uterine artery Doppler. Multivariable regression was used to calculate a predictive model for early-onset FGR (birthweight centile < 3rd/< 10th with absent umbilical end-diastolic flow, < 34 weeks). FGR prevalence was high (10.3%), however early-onset FGR was uncommon (2.3%). Placental screening effectively identified early-onset (area under the curve (AUC) 0.93, 95% confidence interval (CI) 0.87–1.00), but not late-onset FGR (AUC 0.70, 95% CI 0.64–0.75). Internal validation demonstrated robust performance for detection/exclusion of early-onset FGR. In this cohort, utilisation of our proposed algorithm with targeted fetal growth and Doppler surveillance, compared with universal comprehensive surveillance would have avoided 1044 scans, potentiating significant cost-saving for maternity services.


2022 ◽  
Vol 226 (1) ◽  
pp. S535-S536
Author(s):  
Juliana Gevaerd Martins ◽  
Tetsuya Kawakita ◽  
Carole Barake ◽  
Lindsay Gould ◽  
Dana Baraki ◽  
...  

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