DNA damage and repair followingIn vitroexposure to two different forms of titanium dioxide nanoparticles on trout erythrocyte

2011 ◽  
Vol 29 (1) ◽  
pp. 117-127 ◽  
Author(s):  
Durairaj Sekar ◽  
Maria Letizia Falcioni ◽  
Gianni Barucca ◽  
Giancarlo Falcioni
Keyword(s):  
Dna Damage ◽  
Titanium Dioxide ◽  
Titanium Dioxide Nanoparticles ◽  
Dna Damage And Repair ◽  
Trout Erythrocyte

Titanium dioxide nanoparticles induced cytotoxicity, oxidative stress and DNA damage in human amnion epithelial (WISH) cells

2012 ◽  
Vol 26 (2) ◽  
pp. 351-361 ◽  
Author(s):  
Quaiser Saquib ◽  
Abdulaziz A. Al-Khedhairy ◽  
Maqsood A. Siddiqui ◽  
Faisal M. Abou-Tarboush ◽  
Ameer Azam ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Dna Damage ◽  
Titanium Dioxide ◽  
Titanium Dioxide Nanoparticles ◽  
Human Amnion

scholarly journals Titanium Dioxide Nanoparticles Induce DNA Damage and Genetic Instability In vivo in Mice

2009 ◽  
Vol 69 (22) ◽  
pp. 8784-8789 ◽  
Author(s):  
B. Trouiller ◽  
R. Reliene ◽  
A. Westbrook ◽  
P. Solaimani ◽  
R. H. Schiestl
Keyword(s):  
Dna Damage ◽  
Titanium Dioxide ◽  
Genetic Instability ◽  
Titanium Dioxide Nanoparticles

Reduction of DNA damage induced by titanium dioxide nanoparticles through Nrf2 in vitro and in vivo

2015 ◽  
Vol 298 ◽  
pp. 310-319 ◽  
Author(s):  
Zhiqin Shi ◽  
Yujie Niu ◽  
Qian Wang ◽  
Lei Shi ◽  
Huicai Guo ◽  
...  
Keyword(s):  
Dna Damage ◽  
Titanium Dioxide ◽  
Titanium Dioxide Nanoparticles

scholarly journals Genotoxic impact of titanium dioxide nanoparticles on mollusk Mytilus trossulus (Gould, 1850) in marine environment

2018 ◽  
Vol 3 (4) ◽  
pp. 43-50
Author(s):  
S. P. Kukla ◽  
V. V. Slobodskova ◽  
V. P. Chelomin
Keyword(s):  
Dna Damage ◽  
Titanium Dioxide ◽  
Digestive Gland ◽  
Marine Environment ◽  
Titanium Dioxide Nanoparticles ◽  
Titanium Content ◽  
Trophic Levels ◽  
Mytilus Trossulus ◽  
Potential Danger ◽  
Malondialdehyde Content

An increase in the input of titanium dioxide nanoparticles (NP TiO2) into the marine environment can cause unpredictable consequences and create a potential danger to organisms of different trophic levels. Impact of NP TiO2 on the bivalve Mytilus trossulus (Gould, 1850) was studied using the DNA comet method, and the levels of DNA damage were assessed. Shown that 10-day exposure to NP TiO2 at concentrations of 200 and 1000 μg·l-1 leads to destructive changes in the DNA of the gills and of the digestive gland of the mollusks. Difference between DNA damage in two examined tissues was noted. Furthermore, the elevation of titanium content and malondialdehyde content in digestive gland of mollusks was noted.

scholarly journals Comparison of Oxidative Stresses Mediated by Different Crystalline Forms and Surface Modification of Titanium Dioxide Nanoparticles

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Karim Samy El-Said ◽  
Ehab Mostafa Ali ◽  
Koki Kanehira ◽  
Akiyoshi Taniguchi
Keyword(s):  
Oxidative Stress ◽  
Dna Damage ◽  
Titanium Dioxide ◽  
Surface Modification ◽  
Titanium Dioxide Nanoparticles ◽  
Crystalline Form ◽  
Cellular Mechanisms ◽  
Oxidative Stresses ◽  
Wide Range ◽  
Crystalline Forms

Titanium dioxide nanoparticles (TiO2NPs) are manufactured worldwide for use in a wide range of applications. There are two common crystalline forms of TiO2anatase and rutile with different physical and chemical characteristics. We previously demonstrated that an increased DNA damage response is mediated by anatase crystalline form compared to rutile. In the present study, we conjugated TiO2NPs with polyethylene glycol (PEG) in order to reduce the genotoxicity and we evaluated some oxidative stress parameters to obtain information on the cellular mechanisms of DNA damage that operate in response to TiO2NPs different crystalline forms exposure in hepatocarcinoma cell lines (HepG2). Our results indicated a significant increase in oxidative stress mediated by the anatase form of TiO2NPs compared to rutile form. On the other hand, PEG modified TiO2NPs showed a significant decrease in oxidative stress as compared to TiO2NPs. These data suggested that the genotoxic potential of TiO2NPs varies with crystalline form and surface modification.

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