Developmental changes in the optic nerve related to ethanol consumption in pregnant rats: Analysis of the ethanol-exposed optic nerve

Teratology ◽  
1993 ◽  
Vol 48 (4) ◽  
pp. 305-322 ◽  
Author(s):  
Maria Dolores Pinazo-Duran ◽  
Jaime Renau-Piqueras ◽  
Consuelo Guerri
2006 ◽  
Vol 1113 (1) ◽  
pp. 74-85 ◽  
Author(s):  
Matías Hidalgo-Sánchez ◽  
Javier Francisco-Morcillo ◽  
Julio Navascués ◽  
Gervasio Martín-Partido

1989 ◽  
Vol 134 (1) ◽  
pp. 85-102 ◽  
Author(s):  
Masahiro J. Go ◽  
Hideaki Tanaka ◽  
Kunihiko Obata ◽  
Shinobu C. Fujita

2018 ◽  
Vol 16 ◽  
pp. 205873921881967 ◽  
Author(s):  
Tiegang Liu ◽  
Xin Tang ◽  
Ling Yao ◽  
Hui Song

Stromal cell–derived factor 1 (SDF-1) and its receptor CXCR4 have shown to play a role in embryonic development process, regulation of hematopoiesis, mediating immunology response, inflammatory reaction, and metastasis of malignant tumor. Recently, SDF-1 and CXCR4 are also closely related to retinal neovascularization. This study was to investigate the expression of SDF-1 and CXCR4 in the retina after optic nerve injury in pregnant rats so as to reveal its significance. A total of 12 pregnant rats were randomly divided into normal group and experimental group (after 5 days of optic nerve injury), six rats in each group; expressions of SDF-1 as well as CXCR4 in rat retina were detected by immunofluorescence staining and western blot assay. The result of immunofluorescence staining showed that the relative gray scale values of SDF-1 and CXCR4 in the experimental group were significantly higher than those in the normal group ( P < 0.05), and the result of Western blot assay showed that the expression levels of SDF-1 and CXCR4 in the experimental group were significantly higher than those in the normal group ( P < 0.05). In conclusion, SDF-1 and its receptor CXCR4 have abnormal expression in the retina of pregnant rats after optic nerve injury, which may be involved in the occurrence and development of optic nerve injury.


2004 ◽  
Vol 79 (3) ◽  
pp. 351-356 ◽  
Author(s):  
Susanna Popp ◽  
Patrice Maurel ◽  
Julie S. Andersen ◽  
Richard U. Margolis

1988 ◽  
Vol 118 (7) ◽  
pp. 865-870 ◽  
Author(s):  
Sheri Zidenberg-Cherr ◽  
Judith Rosenbaum ◽  
Carl L. Keen

Author(s):  
George G. Cocks ◽  
Louis Leibovitz ◽  
DoSuk D. Lee

Our understanding of the structure and the formation of inorganic minerals in the bivalve shells has been considerably advanced by the use of electron microscope. However, very little is known about the ultrastructure of valves in the larval stage of the oysters. The present study examines the developmental changes which occur between the time of conception to the early stages of Dissoconch in the Crassostrea virginica(Gmelin), focusing on the initial deposition of inorganic crystals by the oysters.The spawning was induced by elevating the temperature of the seawater where the adult oysters were conditioned. The eggs and sperm were collected separately, then immediately mixed for the fertilizations to occur. Fertilized animals were kept in the incubator where various stages of development were stopped and observed. The detailed analysis of the early stages of growth showed that CaCO3 crystals(aragonite), with orthorhombic crystal structure, are deposited as early as gastrula stage(Figuresla-b). The next stage in development, the prodissoconch, revealed that the crystal orientation is in the form of spherulites.


Author(s):  
R. A. Turner ◽  
A. E. Rodin ◽  
D. K. Roberts

There have been many reports which establish a relationship between the pineal and sexual structures, including gonadal hypertrophy after pinealectomy, and gonadal atrophy after injection of pineal homogenates or of melatonin. In order to further delineate this relationship the pineals from 5 groups of female rats were studied by electron microscopy:ControlsPregnant ratsAfter 4 weekly injections of 0.1 mg. estradiol benzoate.After 8 daily injections of 150 mcgm. melatonin (pineal hormone).After 8 daily injections of 3 mg. serotonin (melatonin precursor).No ultrastructural differences were evident between the control, and the pregnancy and melatonin groups. However, the estradiol injected animals exhibited a marked increase in the amount and size of rough endoplasmic reticulum within the pineal cells.


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