2′-deoxy′4′-C-ethynyl-2-fluoroadenosine, a nucleoside reverse transcriptase inhibitor, is highly potent against all human immunodeficiency viruses type 1 and has low toxicity

Hiroshi Ohrui

doi:10.1002/tcr.20078

2′-deoxy′4′-C-ethynyl-2-fluoroadenosine, a nucleoside reverse transcriptase inhibitor, is highly potent against all human immunodeficiency viruses type 1 and has low toxicity

The Chemical Record ◽

10.1002/tcr.20078 ◽

2006 ◽

Vol 6 (3) ◽

pp. 133-143 ◽

Cited By ~ 33

Author(s):

Hiroshi Ohrui

Keyword(s):

Reverse Transcriptase ◽

Nucleoside Reverse Transcriptase Inhibitor ◽

Transcriptase Inhibitor ◽

Human Immunodeficiency Viruses ◽

Low Toxicity ◽

Reverse Transcriptase Inhibitor

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Prolonged Suppression of Human Immunodeficiency Virus Type 1 RNA during Dual Nucleoside Reverse‐Transcriptase–Inhibitor Therapy in Clinical Practice

Clinical Infectious Diseases ◽

10.1086/318143 ◽

2000 ◽

Vol 31 (4) ◽

pp. 1095-1097 ◽

Cited By ~ 1

Author(s):

Craig J. Hoesley ◽

Michael S. Saag ◽

Ashlee Chatham ◽

J. Michael Kilby

Keyword(s):

Human Immunodeficiency Virus ◽

Clinical Practice ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Nucleoside Reverse Transcriptase Inhibitor ◽

Transcriptase Inhibitor ◽

Immunodeficiency Virus ◽

Reverse Transcriptase Inhibitor

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Etravirine: clinical review of a treatment option for HIV type-1-infected patients with non-nucleoside reverse transcriptase inhibitor resistance

Antiviral Therapy ◽

10.3851/imp1651 ◽

2010 ◽

Vol 15 (6) ◽

pp. 803-816 ◽

Cited By ~ 8

Author(s):

William J Towner ◽

Isabel Cassetti ◽

Pere Domingo ◽

Steven Nijs ◽

Thomas N Kakuda ◽

...

Keyword(s):

Reverse Transcriptase ◽

Clinical Review ◽

Treatment Option ◽

Nucleoside Reverse Transcriptase Inhibitor ◽

Transcriptase Inhibitor ◽

Hiv Type 1 ◽

Inhibitor Resistance ◽

Reverse Transcriptase Inhibitor

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The inhibition of human immunodeficiency virus type 1 in vitro by a non-nucleoside reverse transcriptase inhibitor MKC-442, alone and in combination with other anti-HIV compounds

Antiviral Research ◽

10.1016/0166-3542(94)00074-i ◽

1995 ◽

Vol 26 (2) ◽

pp. 173-187 ◽

Cited By ~ 27

Author(s):

T BRENNAN ◽

D TAYLOR ◽

C BRIDGES ◽

J LEYDA ◽

A TYMS

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Nucleoside Reverse Transcriptase Inhibitor ◽

Transcriptase Inhibitor ◽

Immunodeficiency Virus ◽

Reverse Transcriptase Inhibitor ◽

Anti Hiv

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Structure–activity relationship studies of 1-(4-chloro-2,5-dimethoxyphenyl)-3-(3-propoxypropyl)thiourea, a non-nucleoside reverse transcriptase inhibitor of human immunodeficiency virus type-1

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2010.11.003 ◽

2011 ◽

Vol 46 (2) ◽

pp. 447-467 ◽

Cited By ~ 4

Author(s):

Michal Weitman ◽

Keti Lerman ◽

Abraham Nudelman ◽

Dan Thomas Major ◽

Amnon Hizi ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Nucleoside Reverse Transcriptase Inhibitor ◽

Transcriptase Inhibitor ◽

Structure Activity ◽

Immunodeficiency Virus ◽

Reverse Transcriptase Inhibitor

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Characterization of Human Immunodeficiency Virus Type 1 Strains Resistant to the Non-Nucleoside Reverse Transcriptase Inhibitor RD4–2217

Antiviral Chemistry and Chemotherapy ◽

10.1177/095632029901000602 ◽

1999 ◽

Vol 10 (6) ◽

pp. 315-320 ◽

Cited By ~ 4

Author(s):

Masatoshi Fujiwara ◽

Eiichi N Kodama ◽

Masayuki Okamoto ◽

Kenji Tokuhisa ◽

Teruhiko Ide ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Nucleoside Reverse Transcriptase Inhibitor ◽

Transcriptase Inhibitor ◽

Immunodeficiency Virus ◽

Reverse Transcriptase Inhibitor

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Broad Nucleoside Reverse‐Transcriptase Inhibitor Cross‐Resistance in Human Immunodeficiency Virus Type 1 Clinical Isolates

The Journal of Infectious Diseases ◽

10.1086/378281 ◽

2003 ◽

Vol 188 (7) ◽

pp. 992-1000 ◽

Cited By ~ 125

Author(s):

Jeannette M. Whitcomb ◽

Neil T. Parkin ◽

Colombe Chappey ◽

Nicholas S. Hellmann ◽

Christos J. Petropoulos

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Nucleoside Reverse Transcriptase Inhibitor ◽

Transcriptase Inhibitor ◽

Cross Resistance ◽

Immunodeficiency Virus ◽

Reverse Transcriptase Inhibitor

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Multi-nucleoside reverse transcriptase inhibitor resistant HIV type-1 in a patient from Sierra Leone failing stavudine, lamivudine and nevirapine

Antiviral Therapy ◽

10.3851/imp1683 ◽

2011 ◽

Vol 16 (1) ◽

pp. 115-118 ◽

Cited By ~ 3

Author(s):

Raph L Hamers ◽

Annemarie MJ Wensing ◽

Nicole KT Back ◽

Maria S Arcilla ◽

Jos PH Frissen

Keyword(s):

Reverse Transcriptase ◽

Sierra Leone ◽

Nucleoside Reverse Transcriptase Inhibitor ◽

Transcriptase Inhibitor ◽

Hiv Type 1 ◽

Reverse Transcriptase Inhibitor

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Potency of Stampidine Against Multi-Nucleoside Reverse Transcriptase Inhibitor Resistant Human Immunodeficiency Viruses

Arzneimittelforschung ◽

10.1055/s-0031-1296806 ◽

2011 ◽

Vol 56 (02) ◽

pp. 193-203

Author(s):

Fatih Uckun ◽

Taracad Venkatachalam ◽

Sanjive Qazi

Keyword(s):

Reverse Transcriptase ◽

Nucleoside Reverse Transcriptase Inhibitor ◽

Transcriptase Inhibitor ◽

Human Immunodeficiency Viruses ◽

Reverse Transcriptase Inhibitor

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The non-nucleoside reverse transcriptase inhibitor efavirenz stimulates replication of human immunodeficiency virus type 1 harboring certain non-nucleoside resistance mutations

Virology ◽

10.1016/j.virol.2010.03.018 ◽

2010 ◽

Vol 402 (2) ◽

pp. 228-237 ◽

Cited By ~ 10

Author(s):

J. Wang ◽

H. Liang ◽

L. Bacheler ◽

H. Wu ◽

K. Deriziotis ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Nucleoside Reverse Transcriptase Inhibitor ◽

Transcriptase Inhibitor ◽

Resistance Mutations ◽

Immunodeficiency Virus ◽

Reverse Transcriptase Inhibitor

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Faculty Opinions recommendation of Detection of low-level K65R variants in nucleoside reverse transcriptase inhibitor-naive chronic and acute HIV-1 subtype C infections.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12019956.13157054 ◽

2011 ◽

Author(s):

Mark Wainberg ◽

Dimitrios Coutsinos

Keyword(s):

Reverse Transcriptase ◽

Nucleoside Reverse Transcriptase Inhibitor ◽

Transcriptase Inhibitor ◽

Subtype C ◽

Low Level ◽

Acute Hiv ◽

Reverse Transcriptase Inhibitor ◽

Hiv 1

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