Dopamine D1 receptors have subcellular distributions conducive to interactions with prodynorphin in the rat nucleus accumbens shell

Synapse ◽  
2006 ◽  
Vol 60 (1) ◽  
pp. 1-19 ◽  
Author(s):  
Yuko Hara ◽  
Tatiana Yakovleva ◽  
Georgy Bakalkin ◽  
Virginia M. Pickel
Keyword(s):  
Nucleus Accumbens ◽  
D1 Receptors ◽  
Nucleus Accumbens Shell ◽  
Dopamine D1 Receptors ◽  
Rat Nucleus Accumbens

Dopamine D1-Receptors Modulate Lateral Inhibition Between Principal Cells of the Nucleus Accumbens

2005 ◽  
Vol 93 (3) ◽  
pp. 1816-1819 ◽  
Author(s):  
Stefano Taverna ◽  
Barbara Canciani ◽  
Cyriel M. A. Pennartz
Keyword(s):  
Nucleus Accumbens ◽  
Sch 23390 ◽  
Brain Slices ◽  
D1 Receptor ◽  
D1 Receptors ◽  
Projection Neurons ◽  
Dopamine D1 Receptors ◽  
Principal Cells ◽  
Rat Nucleus Accumbens ◽  
Selection Of

One of the current hypotheses on dopamine in the physiology of motivation posits that this neurotransmitter regulates filtering and selection of inputs to the nucleus accumbens. The effects of dopamine (100 μM) and the D1-receptor agonist SKF 38393 (20–50 μM) on GABAergic synaptic transmission between pairs of principal cells of rat nucleus accumbens were studied by using simultaneous dual patch-clamp recordings in acutely prepared brain slices. Both compounds attenuated postsynaptic responses induced by presynaptic firing and this effect was reversed by the D1-receptor antagonist SCH 23390 (25 μM). This attenuating effect of dopamine D1-receptors may act to diminish competitive interactions between single projection neurons or ensembles in the nucleus accumbens.

Nicotine-conditioned single-trial place preference: selective role of nucleus accumbens shell dopamine D1 receptors in acquisition

2005 ◽  
Vol 184 (3-4) ◽  
pp. 447-455 ◽  
Author(s):  
Liliana Spina ◽  
Sandro Fenu ◽  
Rosanna Longoni ◽  
Emilia Rivas ◽  
Gaetano Di Chiara
Keyword(s):  
Nucleus Accumbens ◽  
Place Preference ◽  
D1 Receptors ◽  
Single Trial ◽  
Nucleus Accumbens Shell ◽  
Dopamine D1 Receptors
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