scholarly journals C/EBPβ Regulates Stem Cell Activity and Specifies Luminal Cell Fate in the Mammary Gland

Stem Cells ◽  
2010 ◽  
pp. N/A-N/A ◽  
Author(s):  
Heather L. LaMarca ◽  
Adriana P. Visbal ◽  
Chad J. Creighton ◽  
Hao Liu ◽  
Yiqun Zhang ◽  
...  
Keyword(s):  
Stem Cell ◽  
Mammary Gland ◽  
Cell Fate ◽  
Cell Activity ◽  
Luminal Cell ◽  
Stem Cell Activity

scholarly journals Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland

2007 ◽  
Vol 204 (1) ◽  
pp. i1-i1
Author(s):  
Katherine E. Sleeman ◽  
Howard Kendrick ◽  
David Robertson ◽  
Clare M. Isacke ◽  
Alan Ashworth ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Stem Cell ◽  
Mammary Gland ◽  
Cell Activity ◽  
Receptor Expression ◽  
Estrogen Receptor Expression ◽  
Stem Cell Activity

scholarly journals ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling

2014 ◽  
Vol 16 (10) ◽  
pp. 1004-1015 ◽  
Author(s):  
Rumela Chakrabarti ◽  
Yong Wei ◽  
Julie Hwang ◽  
Xiang Hang ◽  
Mario Andres Blanco ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Stem Cell ◽  
Mammary Gland ◽  
Mammary Gland Development ◽  
Cell Activity ◽  
Wnt Signalling ◽  
Stem Cell Activity ◽  
Basal Like Breast Cancer ◽  
Gland Development

CD24 and CD49f expressions of E14.5 mouse mammary anlagen cells define putative distribution of earlier embryonic mammary stem cell activities

2018 ◽  
Vol 96 (5) ◽  
pp. 539-547 ◽  
Author(s):  
Jiazhe Song ◽  
Fangrong Ding ◽  
Song Li ◽  
Wenzhe Li ◽  
Ning Li ◽  
...  
Keyword(s):  
Stem Cell ◽  
Mammary Gland ◽  
Cell Population ◽  
Cell Biology ◽  
Cell Activity ◽  
Mammary Stem Cell ◽  
Flow Cytometry Analysis ◽  
Large Numbers ◽  
Stem Cell Activity ◽  
Mammary Stem

Stem cell biology offers promise for understanding the origins of the mammary gland. However, the distribution of mammary stem cell (MaSC) activities at earlier embryonic stages has not been fully identified. The markers for sorting adult MaSC, CD24, CD29, and CD49f have been applied to analyze fetal MaSCs. Here we explored mammary anlagen MaSCs by investigating the expression of CD24 and CD49f. According to the comparative analysis between adult mammary gland and fetal mammary anlagen, we found that fetal mouse mammary anlagen may possess a high percentage of potential MaSCs. Flow cytometry analysis revealed 2 distinct mammary anlagen populations: Lin–CD24med and Lin–CD24high. Sphere-forming and mammary repopulating assays confirmed that the stem cell activity of E14.5 mouse mammary anlagen was restricted to the Lin–CD24med cell population. Furthermore, CD24med mammary anlagen cells were separated into Lin–CD24medCD49f+ and Lin–CD24medCD49f– populations and identified, respectively. The results proved that the mammary anlagen Lin–CD24medCD49f+ cell population possesses more stem cell activities than the Lin–CD24medCD49f– cell population. However, a limited numbers of stem cells and large numbers of stromal cells were identified in mammary anlagen in the Lin–CD24med cell population.

scholarly journals Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2

Stem Cells ◽  
2013 ◽  
Vol 31 (9) ◽  
pp. 1921-1931 ◽  
Author(s):  
Ying Wang ◽  
Jie Dong ◽  
Dali Li ◽  
Li Lai ◽  
Stefan Siwko ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Stem Cell ◽  
Mammary Gland ◽  
Mammary Gland Development ◽  
Cell Activity ◽  
Stem Cell Activity ◽  
Gland Development

scholarly journals Resident macrophages influence stem cell activity in the mammary gland

2009 ◽  
Vol 11 (4) ◽  
Author(s):  
David E Gyorki ◽  
Marie-Liesse Asselin-Labat ◽  
Nico van Rooijen ◽  
Geoffrey J Lindeman ◽  
Jane E Visvader
Keyword(s):  
Stem Cell ◽  
Mammary Gland ◽  
Cell Activity ◽  
Stem Cell Activity
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