scholarly journals Immunogenicity of Thrombopoietin Mimetic Peptide GW395058 in BALB/c Mice and New Zealand White Rabbits: Evaluation of the Potential for Thrombopoietin Neutralizing Antibody Production in Man

Stem Cells ◽  
1999 ◽  
Vol 17 (4) ◽  
pp. 203-209 ◽  
Author(s):  
Mark De Serres ◽  
Byron Ellis ◽  
John E. Dillberger ◽  
Sharon K. Rudolph ◽  
Jeff T. Hutchins ◽  
...  
Keyword(s):  
New Zealand ◽  
Antibody Production ◽  
Neutralizing Antibody ◽  
Mimetic Peptide ◽  
Thrombopoietin Mimetic Peptide ◽  
New Zealand White Rabbits ◽  
Thrombopoietin Mimetic

Pharmacodynamics and Pharmacokinetics of the Novel Thrombopoietin Mimetic Peptide RWJ-800088 in Humans

2008 ◽  
Vol 84 (4) ◽  
pp. 481-487 ◽  
Author(s):  
M Liem-Moolenaar ◽  
D Cerneus ◽  
CJ Molloy ◽  
D End ◽  
KH Brown ◽  
...  
Keyword(s):  
The Novel ◽  
Mimetic Peptide ◽  
Thrombopoietin Mimetic Peptide ◽  
Thrombopoietin Mimetic

scholarly journals Enhanced inflammation in New Zealand white rabbits when MERS-CoV reinfection occurs in the absence of neutralizing antibody

2017 ◽  
Vol 13 (8) ◽  
pp. e1006565 ◽  
Author(s):  
Katherine V. Houser ◽  
Andrew J. Broadbent ◽  
Lisa Gretebeck ◽  
Leatrice Vogel ◽  
Elaine W. Lamirande ◽  
...  
Keyword(s):  
New Zealand ◽  
Neutralizing Antibody ◽  
New Zealand White Rabbits

A Cytochemical Study of Glucose-6-Phosphatase (G-6-PASE) in Cells Participating in Atherogenesis of Rabbit Aorta

1975 ◽  
Vol 33 ◽  
pp. 460-461
Author(s):  
Sidney D. Kobernick ◽  
Edna A. Elfont ◽  
Neddra L. Brooks
Keyword(s):  
Lipid Metabolism ◽  
New Zealand ◽  
Aortic Wall ◽  
Rabbit Aorta ◽  
Plaque Formation ◽  
Metabolic Changes ◽  
Atherosclerotic Plaques ◽  
Cytochemical Study ◽  
Cellular Alteration ◽  
New Zealand White Rabbits

This cytochemical study was designed to investigate early metabolic changes in the aortic wall that might lead to or accompany development of atherosclerotic plaques in rabbits. The hypothesis that the primary cellular alteration leading to plaque formation might be due to changes in either carbohydrate or lipid metabolism led to histochemical studies that showed elevation of G-6-Pase in atherosclerotic plaques of rabbit aorta. This observation initiated the present investigation to determine how early in plaque formation and in which cells this change could be observed.Male New Zealand white rabbits of approximately 2000 kg consumed normal diets or diets containing 0.25 or 1.0 gm of cholesterol per day for 10, 50 and 90 days. Aortas were injected jin situ with glutaraldehyde fixative and dissected out. The plaques were identified, isolated, minced and fixed for not more than 10 minutes. Incubation and postfixation proceeded as described by Leskes and co-workers.

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