scholarly journals Upconversion Nanoparticles: Rattle-Structured Upconversion Nanoparticles for Near-IR-Induced Suppression of Alzheimer's β-Amyloid Aggregation (Small 11/2017)

Small ◽  
2017 ◽  
Vol 13 (11) ◽  
Author(s):  
Sukeun Kuk ◽  
Byung Il Lee ◽  
Joon Seok Lee ◽  
Chan Beum Park
Keyword(s):  
Upconversion Nanoparticles ◽  
Amyloid Aggregation ◽  
Near Ir ◽  
Β Amyloid

Rattle-Structured Upconversion Nanoparticles for Near-IR-Induced Suppression of Alzheimer's β-Amyloid Aggregation

Small ◽  
2017 ◽  
Vol 13 (11) ◽  
pp. 1603139 ◽  
Author(s):  
Sukeun Kuk ◽  
Byung Il Lee ◽  
Joon Seok Lee ◽  
Chan Beum Park
Keyword(s):  
Upconversion Nanoparticles ◽  
Amyloid Aggregation ◽  
Near Ir ◽  
Β Amyloid

Аnticholinesterase and antioxidant activity of new binary conjugates of (с)-carbolines

2019 ◽  
Vol 484 (1) ◽  
pp. 104-108
Author(s):  
G. F. Makhaeva ◽  
E. F. Shevtsova ◽  
N. P. Boltneva ◽  
N. V. Kovaleva ◽  
E. V. Rudakova ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Antioxidant Activity ◽  
Anticholinesterase Activity ◽  
Amyloid Aggregation ◽  
Varying Length ◽  
Β Amyloid ◽  
New Compounds

This study presents the synthesis of binary tetrohydro-γ-carbolines with ditriazol spacers of varying length, which exhibit anticholinesterase and antioxidant activity, as compared to the original Dimebon prototype. Anticholinesterase activity suggests the potential ability of the new compounds to block β-amyloid aggregation induced by anticholinesterase, making them promising candidates for further research preparations for the treatment of Alzheimer's disease. Particular attention should be paid to the conjugate with an intertriazol hexamethylene spacer, which can be regarded as the leading compound in this series.

Rutin inhibits β-amyloid aggregation and cytotoxicity, attenuates oxidative stress, and decreases the production of nitric oxide and proinflammatory cytokines

2012 ◽  
Vol 33 (3) ◽  
pp. 482-490 ◽  
Author(s):  
Shao-wei Wang ◽  
Yu-Jiong Wang ◽  
Ya-jing Su ◽  
Wei-wei Zhou ◽  
Shi-gao Yang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Nitric Oxide ◽  
Proinflammatory Cytokines ◽  
Amyloid Aggregation ◽  
Β Amyloid

Role of Acetylcholinesterase in β-Amyloid Aggregation Studied by Accelerated Molecular Dynamics

2016 ◽  
Vol 7 (2) ◽  
pp. 396-402 ◽  
Author(s):  
Sofya V. Lushchekina ◽  
Ekaterina D. Kots ◽  
Dana A. Novichkova ◽  
Konstantin A. Petrov ◽  
Patrick Masson
Keyword(s):  
Molecular Dynamics ◽  
Amyloid Aggregation ◽  
Accelerated Molecular Dynamics ◽  
Β Amyloid

β-Amyloid aggregation induced by human acetylcholinesterase: inhibition studies

2003 ◽  
Vol 65 (3) ◽  
pp. 407-416 ◽  
Author(s):  
Manuela Bartolini ◽  
Carlo Bertucci ◽  
Vanni Cavrini ◽  
Vincenza Andrisano
Keyword(s):  
Acetylcholinesterase Inhibition ◽  
Amyloid Aggregation ◽  
Β Amyloid ◽  
Inhibition Studies

Design and Synthesis of 2-Substitutedphenyl Benzo[D]Thiazole Derivatives and Their β-Amyloid Aggregation and Cholinesterase Inhibitory Activities

2019 ◽  
Vol 53 (4) ◽  
pp. 322-328 ◽  
Author(s):  
Merve Zengin ◽  
Oya Unsal-Tan ◽  
Tuba Tüylü Küçükkılınç ◽  
Beyza Ayazgok ◽  
Ayla Balkan
Keyword(s):  
Amyloid Aggregation ◽  
Thiazole Derivatives ◽  
Design And Synthesis ◽  
Β Amyloid ◽  
Inhibitory Activities
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