Interference of Steroidogenesis by Gold Nanorod Core/Silver Shell Nanostructures: Implications for Reproductive Toxicity of Silver Nanomaterials

Small ◽  
2016 ◽  
Vol 13 (10) ◽  
pp. 1602855 ◽  
Author(s):  
Xiumei Jiang ◽  
Liming Wang ◽  
Yinglu Ji ◽  
Jinglong Tang ◽  
Xin Tian ◽  
...  
Keyword(s):  
Reproductive Toxicity ◽  
Gold Nanorod ◽  
Shell Nanostructures ◽  
Silver Nanomaterials ◽  
Silver Shell

Single-Dosed Genotoxicity Study of Gold Nanorod Core/Silver Shell Nanostructures by Pig-a, Micronucleus, and Comet Assays

2018 ◽  
Vol 14 (11) ◽  
pp. 1953-1964 ◽  
Author(s):  
Dan Wang ◽  
Mo Dan ◽  
Yinglu Ji ◽  
Xiaochun Wu ◽  
Liming Xu ◽  
...  
Keyword(s):  
Gold Nanorod ◽  
Shell Nanostructures ◽  
Silver Shell

scholarly journals In Vivo Metabolic Response upon Exposure to Gold Nanorod Core/Silver Shell Nanostructures: Modulation of Inflammation and Upregulation of Dopamine

2020 ◽  
Vol 21 (2) ◽  
pp. 384 ◽  
Author(s):  
Haiyun Li ◽  
Tao Wen ◽  
Tao Wang ◽  
Yinglu Ji ◽  
Yaoyi Shen ◽  
...  
Keyword(s):  
Rational Design ◽  
Molecular Mechanisms ◽  
Metabolic Response ◽  
Dopamine Metabolism ◽  
Gold Nanorod ◽  
Ag Nps ◽  
Shell Nanostructures ◽  
Antioxidant Defense Systems ◽  
Silver Shell

With the increasing applications of silver nanoparticles (Ag NPs), the concerns of widespread human exposure as well as subsequent health risks have been continuously growing. The acute and chronic toxicities of Ag NPs in cellular tests and animal tests have been widely investigated. Accumulating evidence shows that Ag NPs can induce inflammation, yet the overall mechanism is incomplete. Herein, using gold nanorod core/silver shell nanostructures (Au@Ag NRs) as a model system, we studied the influence on mice liver and lungs from the viewpoint of metabolism. In agreement with previous studies, Au@Ag NRs’ intravenous exposure caused inflammatory reaction, accompanying with metabolic alterations, including energy metabolism, membrane/choline metabolism, redox metabolism, and purine metabolism, the disturbances of which contribute to inflammation. At the same time, dopamine metabolism in liver was also changed. This is the first time to observe the production of dopamine in non-neural tissue after treatment with Ag NPs. As the upregulation of dopamine resists inflammation, it indicates the activation of antioxidant defense systems against oxidative stress induced by Au@Ag NRs. In the end, our findings deepened the understanding of molecular mechanisms of Ag NPs-induced inflammation and provide assistance in the rational design of their biomedical applications.

Initiation of protective autophagy in hepatocytes by gold nanorod core/silver shell nanostructures

Nanoscale ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 6429-6437 ◽  
Author(s):  
Haiyun Li ◽  
Jiaqi Chen ◽  
Huizhen Fan ◽  
Rui Cai ◽  
Xinshuang Gao ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Human Hepatocytes ◽  
Gold Nanorod ◽  
Shell Nanostructures ◽  
Lethal Doses ◽  
Silver Shell

At sub-lethal doses, Au@Ag NRs induce oxidative stress that activates the protective autophagy of human hepatocytes.

scholarly journals Sonication-assisted synthesis of multi-functional gold nanorod/silica core–shell nanostructures

2013 ◽  
Vol 551 ◽  
pp. 405-409 ◽  
Author(s):  
Jun Liu ◽  
Meng-Jie Chang ◽  
Bao Gao ◽  
Zhu-Guo Xu ◽  
Hao-Li Zhang
Keyword(s):  
Gold Nanorod ◽  
Core Shell ◽  
Shell Nanostructures ◽  
Silica Core

(Gold triangular nanoplate core)@(silver shell) nanostructures as highly sensitive and selective plasmonic nanoprobes for hydrogen sulfide detection

Nanoscale ◽  
2020 ◽  
Vol 12 (39) ◽  
pp. 20250-20257 ◽  
Author(s):  
Hua Mi ◽  
Shengyan Wang ◽  
Hang Yin ◽  
Le Wang ◽  
Lin Mei ◽  
...  
Keyword(s):  
Refractive Index ◽  
Hydrogen Sulfide ◽  
High Refractive Index ◽  
Great Sensitivity ◽  
Refractive Index Sensitivity ◽  
Shell Nanostructures ◽  
Highly Sensitive ◽  
Index Sensitivity ◽  
Silver Shell

AuTNP@Ag nanostructures are developed as nanoprobes for hydrogen sulfide. Owing to the high refractive index sensitivity of Au TNPs and facile sulfurization of silver, AuTNP@Ag nanostructures exhibit great sensitivity to both sulfur ions and H2S gas.

Efficient Near-IR Hyperthermia and Intense Nonlinear Optical Imaging Contrast on the Gold Nanorod-in-Shell Nanostructures

2009 ◽  
Vol 131 (40) ◽  
pp. 14186-14187 ◽  
Author(s):  
Kuo-Wei Hu ◽  
Tzu-Ming Liu ◽  
Kuei-Yi Chung ◽  
Keng-Shiang Huang ◽  
Chien-Tai Hsieh ◽  
...  
Keyword(s):  
Optical Imaging ◽  
Nonlinear Optical ◽  
Gold Nanorod ◽  
Shell Nanostructures ◽  
Near Ir ◽  
Nonlinear Optical Imaging

Motor coordination dysfunction induced by gold nanorods core/silver shell nanostructures in mice: disruption in mitochondrial transport and neurotransmitter release

RSC Advances ◽  
2014 ◽  
Vol 4 (103) ◽  
pp. 59472-59480
Author(s):  
Nan Yang ◽  
Yanyong Liu ◽  
Yinglu Ji ◽  
Zhili Ren ◽  
Jie Meng ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Gold Nanorods ◽  
Neurotransmitter Release ◽  
Motor Coordination ◽  
Mitochondrial Transport ◽  
Shell Nanostructures ◽  
Risk Of Exposure ◽  
Silver Shell

The risk of exposure to silver nanoparticles (AgNPs) is becoming increasingly widespread and causes great concern.

Preparation of monodisperse bimetallic nanorods with gold nanorod core and silver shell and their plasmonic property and SERS efficiency

2014 ◽  
Vol 45 (6) ◽  
pp. 431-437 ◽  
Author(s):  
Xu Dong ◽  
Jianfeng Zhou ◽  
Xiaoyun Liu ◽  
Danli Lin ◽  
Liusheng Zha
Keyword(s):  
Gold Nanorod ◽  
Plasmonic Property ◽  
Bimetallic Nanorods ◽  
Silver Shell
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