scholarly journals CXCR-4 Targeted, Short Wave Infrared (SWIR) Emitting Nanoprobes for Enhanced Deep Tissue Imaging and Micrometastatic Cancer Lesion Detection

Small ◽  
2015 ◽  
Vol 11 (47) ◽  
pp. 6347-6357 ◽  
Author(s):  
Margot Zevon ◽  
Vidya Ganapathy ◽  
Harini Kantamneni ◽  
Marco Mingozzi ◽  
Paul Kim ◽  
...  
Keyword(s):  
Short Wave ◽  
Lesion Detection ◽  
Tissue Imaging ◽  
Deep Tissue ◽  
Deep Tissue Imaging ◽  
Short Wave Infrared ◽  
Cancer Lesion

scholarly journals Cancer-targeted short-wave infra-red emitting rare-earth albumin nanocomposites for lesion mapping and deep-tissue imaging

2016 ◽  
Vol 4 ◽  
Author(s):  
Zevon Margot ◽  
Ganapathy Vidya ◽  
Kantamneni Harini ◽  
Higgins Laura ◽  
Mingozzi Marco ◽  
...  
Keyword(s):  
Rare Earth ◽  
Short Wave ◽  
Tissue Imaging ◽  
Deep Tissue ◽  
Lesion Mapping ◽  
Infra Red ◽  
Deep Tissue Imaging

Two-Dimensional Near-Infrared and Shortwave Infrared Molecular Aggregates: Taking Kasha’s Model to the Next Dimension

2019 ◽  
Author(s):  
Arundhati Deshmukh ◽  
Danielle Koppel ◽  
Chern Chuang ◽  
Danielle Cadena ◽  
Jianshu Cao ◽  
...  
Keyword(s):  
Near Infrared ◽  
Photophysical Properties ◽  
Satellite Telemetry ◽  
Transition Dipole Moment ◽  
Short Wave ◽  
Tissue Imaging ◽  
Transition Dipole ◽  
Deep Tissue Imaging ◽  
Excitonic States ◽  
Shortwave Infrared

Technologies which utilize near-infrared (700 – 1000 nm) and short-wave infrared (1000 – 2000 nm) electromagnetic radiation have applications in deep-tissue imaging, telecommunications and satellite telemetry due to low scattering and decreased background signal in this spectral region. However, there are few molecular species, which absorb efficiently beyond 1000 nm. Transition dipole moment coupling (e.g. J-aggregation) allows for redshifted excitonic states and provides a pathway to highly absorptive electronic states in the infrared. We present aggregates of two cyanine dyes whose absorption peaks redshift dramatically upon aggregation in water from ~ 800 nm to 1000 nm and 1050 nm with sheet-like morphologies and high molar absorptivities (e ~ 10<sup>5 </sup>M<sup>-1</sup>cm<sup>-1</sup>). To describe this phenomenology, we extend Kasha’s model for J- and H-aggregation to describe the excitonic states of <i> 2-dimensional aggregates</i> whose slip is controlled by steric hindrance in the assembled structure. A consequence of the increased dimensionality is the phenomenon of an <i>intermediate </i>“I-aggregate”, one which redshifts yet displays spectral signatures of band-edge dark states akin to an H-aggregate. We distinguish between H-, I- and J-aggregates by showing the relative position of the bright (absorptive) state within the density of states using temperature dependent spectroscopy. Our results can be used to better design chromophores with predictable and tunable aggregation with new photophysical properties.

Responsive optical probes for deep-tissue imaging: Photoacoustics and second near-infrared fluorescence

2021 ◽  
Vol 173 ◽  
pp. 141-163
Author(s):  
Fei Ding ◽  
Jing Feng ◽  
Xueli Zhang ◽  
Jielin Sun ◽  
Chunhai Fan ◽  
...  
Keyword(s):  
Near Infrared ◽  
Tissue Imaging ◽  
Deep Tissue ◽  
Optical Probes ◽  
Near Infrared Fluorescence ◽  
Deep Tissue Imaging

scholarly journals Slow light for deep tissue imaging with ultrasound modulation

2012 ◽  
Vol 100 (13) ◽  
pp. 131102 ◽  
Author(s):  
Huiliang Zhang ◽  
Mahmood Sabooni ◽  
Lars Rippe ◽  
Chulhong Kim ◽  
Stefan Kröll ◽  
...  
Keyword(s):  
Slow Light ◽  
Tissue Imaging ◽  
Deep Tissue ◽  
Deep Tissue Imaging ◽  
Ultrasound Modulation

scholarly journals Transgenic mice: beyond the knockout

2011 ◽  
Vol 300 (2) ◽  
pp. F291-F300 ◽  
Author(s):  
R. Lance Miller
Keyword(s):  
Transgenic Mice ◽  
Fluorescent Proteins ◽  
Primary Cultures ◽  
Cell Lineage ◽  
Tissue Imaging ◽  
Cell Type ◽  
Deep Tissue ◽  
Pure Cell ◽  
Deep Tissue Imaging ◽  
Tremendous Impact

Transgenic mice have had a tremendous impact on biomedical research. Most researchers are familiar with transgenic mice that carry Cre recombinase (Cre) and how they are used to create conditional knockouts. However, some researchers are less familiar with many of the other types of transgenic mice and their applications. For example, transgenic mice can be used to study biochemical and molecular pathways in primary cultures and cell suspensions derived from transgenic mice, cell-cell interactions using multiple fluorescent proteins in the same mouse, and the cell cycle in real time and in the whole animal, and they can be used to perform deep tissue imaging in the whole animal, follow cell lineage during development and disease, and isolate large quantities of a pure cell type directly from organs. These novel transgenic mice and their applications provide the means for studying of molecular and biochemical events in the whole animal that was previously limited to cell cultures. In conclusion, transgenic mice are not just for generating knockouts.

Designing Upconversion Nanocrystals Capable of 745 nm Sensitization and 803 nm Emission for Deep-Tissue Imaging

2016 ◽  
Vol 22 (31) ◽  
pp. 10801-10807 ◽  
Author(s):  
Liangliang Liang ◽  
Xiaoji Xie ◽  
Daniel Teh Boon Loong ◽  
Angelo Homayoun All ◽  
Ling Huang ◽  
...  
Keyword(s):  
Tissue Imaging ◽  
Deep Tissue ◽  
Upconversion Nanocrystals ◽  
Deep Tissue Imaging

scholarly journals Near-infrared probe-based confocal microendoscope for deep-tissue imaging

2018 ◽  
Vol 9 (10) ◽  
pp. 5011 ◽  
Author(s):  
Jiafu Wang ◽  
Hua Li ◽  
Geng Tian ◽  
Yong Deng ◽  
Qian Liu ◽  
...  
Keyword(s):  
Near Infrared ◽  
Tissue Imaging ◽  
Deep Tissue ◽  
Deep Tissue Imaging

The one-pot synthesis of core/shell/shell CdTe/CdSe/ZnSe quantum dots in aqueous media for in vivo deep tissue imaging

2011 ◽  
Vol 21 (9) ◽  
pp. 2877 ◽  
Author(s):  
Shohei Taniguchi ◽  
Mark Green ◽  
Sarwat B. Rizvi ◽  
Alexander Seifalian
Keyword(s):  
Quantum Dots ◽  
Aqueous Media ◽  
Tissue Imaging ◽  
Core Shell ◽  
Deep Tissue ◽  
One Pot ◽  
One Pot Synthesis ◽  
Deep Tissue Imaging ◽  
The One
Sign in / Sign up

Export Citation Format

Share Document