A Site‐Selective C−N Bond Formation of 2,4‐Dichloro‐5 H ‐pyrano[2,3‐ d ]pyrimidines and Amide

2021 ◽  
Vol 6 (43) ◽  
pp. 12032-12035
Author(s):  
Jinjing Qin ◽  
Zhenhua Li ◽  
Yingyan Cao ◽  
Yuanyuan Xie ◽  
Weike Su
Keyword(s):  
Bond Formation ◽  
A Site ◽  
Site Selective

Chemical and Electrochemical Heteroepitaxial Growth of Chalcogenide Semiconductors from Solutions

1996 ◽  
Vol 451 ◽  
Author(s):  
D. Lincot ◽  
M. J. Furlong ◽  
M. Froment ◽  
R. Cortes ◽  
M. C. Bernard
Keyword(s):  
Heteroepitaxial Growth ◽  
X Ray Diffraction ◽  
Basic Principles ◽  
Lattice Match ◽  
X Ray ◽  
Chalcogenide Semiconductors ◽  
Influence Of Temperature On ◽  
Deposition Processes ◽  
A Site ◽  
Site Selective

ABSTRACTChalcogenide semiconductors have been deposited epitaxially from aqueous solutions either chemically or electrochemically at growth rates of up to 0.7 μmhr−1. After recalling the basic principles of these deposition processes, results are presented concerning chemically deposited CdS on InP, GaP and CuInSe2 substrates, electrodeposited CdTe on InP, and CdSAnP heterostructures. Characterisation of these structures by RHEED, TEM, HRTEM, and glazing angle X ray diffraction allows to analyse the effects of substrate orientation, polarity, lattice match plus the influence of temperature on epitaxial growth. These results are discussed in terms of self organisation and a site selective growth mechanisms due to the free enegy of formation of each compound.

Recent Advances in C–Br Bond Formation

Synlett ◽  
2021 ◽  
Author(s):  
Ying-Yeung Yeung ◽  
Jonathan Wong
Keyword(s):  
Organic Synthesis ◽  
Aromatic Compounds ◽  
Bond Formation ◽  
Cross Coupling ◽  
Catalytic Site ◽  
Atom Transfer ◽  
Bond Forming ◽  
Recent Advances ◽  
Catalytic Asymmetric ◽  
Site Selective

AbstractOrganobromine compounds are extremely useful in organic synthesis. In this perspective, a focused discussion on some recent advancements in C–Br bond-forming reactions is presented.1 Introduction2 Selected Recent Advances2.1 Catalytic Asymmetric Bromopolycyclization of Olefinic Substrates2.2 Catalytic Asymmetric Intermolecular Bromination2.3 Some New Catalysts and Reagents for Bromination2.4 Catalytic Site-Selective Bromination of Aromatic Compounds2.5 sp3 C–H Bromination via Atom Transfer/Cross-Coupling3 Outlook

Abstract 1304: AbYlinkTM: A site-selective labeling method for preclinical imaging of therapeutic antibodies

2021 ◽  
Author(s):  
Viktoriia Postupalenko ◽  
Léo Marx ◽  
David Viertl ◽  
Natalia Gasilova ◽  
Mathilde Plantin ◽  
...  
Keyword(s):  
Therapeutic Antibodies ◽  
Selective Labeling ◽  
Preclinical Imaging ◽  
A Site ◽  
Site Selective ◽  
Labeling Method

Catalyst-Controlled Site-Selective N-H and C3-Arylation of Carba-zole via Carbene Transfer Reactions

2021 ◽  
Author(s):  
Sourav Sekhar Bera ◽  
Srishti Ballabh Bahukhandi ◽  
Claire Empel ◽  
Rene M Koenigs
Keyword(s):  
Transfer Reactions ◽  
Palladium Acetate ◽  
Direct Arylation ◽  
Carbene Transfer ◽  
A Site ◽  
Site Selective

A site-selective direct arylation reaction of carbazole and other N-heterocycles with diazo-naphthalen-2(1H)-ones has been developed. While Au(I)-NHC catalysts lead to selective C3-arylation, palladium acetate allows for selective N-H arylation, displaying...

Nickel-Catalyzed Regioselective Carbomagnesation of Methylenecyclopropanes through a Site-Selective Carbon-Carbon Bond Cleavage

2009 ◽  
Vol 49 (1) ◽  
pp. 144-147 ◽  
Author(s):  
Jun Terao ◽  
Masahiro Tomita ◽  
Surya Prakash Singh ◽  
Nobuaki Kambe
Keyword(s):  
Bond Cleavage ◽  
Carbon Bond ◽  
Carbon Carbon Bond ◽  
A Site ◽  
Site Selective

scholarly journals Site-Selective C-C Modification of Proteins at Neutral pH Using Organocatalyst-Mediated Cross Aldol Ligations

2018 ◽  
Author(s):  
Martin A. Fascione ◽  
Richard J. Spears ◽  
Robin L. Brabham ◽  
Darshita Budhadev ◽  
Tessa Keenan ◽  
...  
Keyword(s):  
Small Molecules ◽  
Stable Carbon ◽  
Biological Mechanisms ◽  
Large Excess ◽  
Reaction Conditions ◽  
Chemical Methods ◽  
Neutral Ph ◽  
Chemical Modification Of Proteins ◽  
A Site ◽  
Site Selective

The bioconjugation of proteins with small molecules has proved an invaluable strategy for probing and perturbing dynamic biological mechanisms. The general use of chemical methods for the functionalisation of proteins remains limited however by the frequent requirement for complicated reaction partners to be present in large excess, and harsh reaction conditions which are incompatible with many protein scaffolds. Herein we describe a site-selective organocatalyst-mediated protein aldol ligation (OPAL) that affords stable carbon-carbon linked bioconjugates at neutral pH under biocompatible conditions. OPAL enables rapid chemical modification of proteins within an hour using simple aldehyde probes in minimal excess, and is utilised here in the selective affinity tagging of proteins in cell lysate. Furthermore we demonstrate that the b-hydroxy aldehyde product of the OPAL can be functionalised a second time at neutral pH in a subsequent organocatalyst-mediated oxime ligation. This tandem strategy is showcased in the ‘chemical mimicry’ of a previously inaccessible natural dual post-translationally modified protein integral to the pathogenesis of the neglected tropical disease Leishmaniasis. <br>

scholarly journals Site-Selective C−S Bond Formation at C−Br over C−OTf and C−Cl Enabled by an Air-Stable, Easily Recoverable, and Recyclable Palladium(I) Catalyst

2018 ◽  
Vol 57 (38) ◽  
pp. 12425-12429 ◽  
Author(s):  
Thomas Scattolin ◽  
Erdem Senol ◽  
Guoyin Yin ◽  
Qianqian Guo ◽  
Franziska Schoenebeck
Keyword(s):  
Bond Formation ◽  
Site Selective

Building Addressable Libraries: Olefin Functionalization Reactions and the Development of a Site-Selective, Cleavable Linker

2021 ◽  
Vol MA2021-01 (42) ◽  
pp. 1727-1727
Author(s):  
Nai-Hua Yeh ◽  
Albert Huang ◽  
Kevin D Moeller
Keyword(s):  
A Site ◽  
Site Selective

scholarly journals A general method for site-selective Csp3–S bond formation via cooperative catalysis

2020 ◽  
Vol 11 (5) ◽  
pp. 1276-1282 ◽  
Author(s):  
Yuman Qin ◽  
Yujie Han ◽  
Yongzhen Tang ◽  
Junfa Wei ◽  
Mingyu Yang
Keyword(s):  
Functional Group ◽  
Bond Formation ◽  
Aliphatic Amines ◽  
Cooperative Catalysis ◽  
Site Selective ◽  
General Method

A copper-catalyzed site-selective thiolation of Csp3–H bonds of aliphatic amines was developed. The method features a broad substrate scope and good functional group tolerance.

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