scholarly journals Bioelectrochemical Chain Elongation of Short‐Chain Fatty Acids Creates Steering Opportunities for Selective Formation of n‐ Butyrate, n‐ Valerate or n‐ Caproate

2020 ◽  
Vol 5 (29) ◽  
pp. 9127-9133
Author(s):  
Sanne M. T. Raes ◽  
Ludovic Jourdin ◽  
Cees J. N. Buisman ◽  
David P. B. T. B. Strik
Keyword(s):  
Fatty Acids ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Chain Elongation ◽  
Selective Formation ◽  
Chain Fatty Acids

Sustainable production of medium chain fatty acids (MCFA) with an enriched mixed bacterial culture: microbial characterization using molecular methods

2018 ◽  
Vol 2 (2) ◽  
pp. 372-380 ◽  
Author(s):  
M. Venkateswar Reddy ◽  
S. Venkata Mohan ◽  
Young-Cheol Chang
Keyword(s):  
Fatty Acids ◽  
Bacterial Culture ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Chain Elongation ◽  
Mixed Bacterial Culture ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Microbial Characterization ◽  
Chain Fatty Acids

Chain elongation is the process by which bacteria convert ethanol and short chain fatty acids (SCFA) into medium chain fatty acids (MCFA).

Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids

2013 ◽  
Vol 305 (12) ◽  
pp. G900-G910 ◽  
Author(s):  
Gijs den Besten ◽  
Katja Lange ◽  
Rick Havinga ◽  
Theo H. van Dijk ◽  
Albert Gerding ◽  
...  
Keyword(s):  
Fatty Acids ◽  
De Novo ◽  
Glucose Production ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Whole Body ◽  
Chain Elongation ◽  
Expression Of Genes ◽  
Total Glucose ◽  
Chain Fatty Acids

Acetate, propionate, and butyrate are the main short-chain fatty acids (SCFAs) that arise from the fermentation of fibers by the colonic microbiota. While many studies focus on the regulatory role of SCFAs, their quantitative role as a catabolic or anabolic substrate for the host has received relatively little attention. To investigate this aspect, we infused conscious mice with physiological quantities of stable isotopes [1-13C]acetate, [2-13C]propionate, or [2,4-13C2]butyrate directly in the cecum, which is the natural production site in mice, and analyzed their interconversion by the microbiota as well as their metabolism by the host. Cecal interconversion, pointing to microbial cross-feeding, was high between acetate and butyrate, low between butyrate and propionate, and almost absent between acetate and propionate. As much as 62% of infused propionate was used in whole body glucose production, in line with its role as gluconeogenic substrate. Conversely, glucose synthesis from propionate accounted for 69% of total glucose production. The synthesis of palmitate and cholesterol in the liver was high from cecal acetate (2.8 and 0.7%, respectively) and butyrate (2.7 and 0.9%, respectively) as substrates, but low or absent from propionate (0.6 and 0.0%, respectively). Label incorporation due to chain elongation of stearate was approximately eightfold higher than de novo synthesis of stearate. Microarray data suggested that SCFAs exert a mild regulatory effect on the expression of genes involved in hepatic metabolic pathways during the 6-h infusion period. Altogether, gut-derived acetate, propionate, and butyrate play important roles as substrates for glucose, cholesterol, and lipid metabolism.

Effect of short-chain fatty acids on the ethylene pathway in embryonic axes of Cicer arietinum during germination

1994 ◽  
Vol 92 (4) ◽  
pp. 629-635 ◽  
Author(s):  
Mercedes Gallardo ◽  
Paloma Munoz De Rueda ◽  
Angel Jesus Matilla ◽  
Isabel Maria Sanchez-Calle
Keyword(s):  
Fatty Acids ◽  
Cicer Arietinum ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Embryonic Axes ◽  
Chain Fatty Acids

Short-Chain Fatty Acids Prevent Diabetic Nephropathy In Vivo and In Vitro

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 92-OR ◽  
Author(s):  
WEI HUANG ◽  
YONG XU ◽  
YOUHUA XU ◽  
LUPING ZHOU ◽  
CHENLIN GAO
Keyword(s):  
Fatty Acids ◽  
Diabetic Nephropathy ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Chain Fatty Acids

1898-P: Colonic Short-Chain Fatty Acids Lower Endogenous Glucose Production

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1898-P
Author(s):  
ADELINA I.L. LANE ◽  
SAVANNA N. WENINGER ◽  
FRANK DUCA
Keyword(s):  
Fatty Acids ◽  
Glucose Production ◽  
Short Chain Fatty Acids ◽  
Endogenous Glucose Production ◽  
Short Chain ◽  
Endogenous Glucose ◽  
Chain Fatty Acids

Concentrations and Correlations of Faecal Short-chain Fatty Acids and Faecal Water Content in Man

1994 ◽  
Vol 7 (6) ◽  
Author(s):  
U. Siigur ◽  
K. E. Norin ◽  
G. Allgood ◽  
T. Schlagheck ◽  
Tore Midtvedt
Keyword(s):  
Fatty Acids ◽  
Water Content ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Chain Fatty Acids
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